NFL DOG HAS WEAPONS vs SINGLE DIMENSIONAL...
- Handicapper
- Wayne Root
- League
- NFL
- Competition
- San Francisco 49ers vs Arizona Cardinals
- Release Date
- 11/15/2025 10:35 PM
- Event Date
- 11/16/2025 04:05 PM
- Bet Type
- Point Spread
- Pick
-
Arizona Cardinals +3.5 (-110)
(BetMGM)
- Outcome
- Loss
- Analysis
- Chairman on Arizona
The 49ers might have Brock Purdy back for this game, but their defense is getting shredded right now. Brock Purdy sounds like he may return this week, but if he is out, we will see Mac Jones once again. Christian McCaffrey has led the offense with 626 rushing yards and 692 receiving yards with eight total touchdowns this season. The 49ers definitely appear to be one-dimensional. Arizona lost their last game at Seattle. Prior to that game, Arizona defeated the Cowboys by a score of 27-17, but lost to the Packers by a score of 27-23 before that. Arizona is progressing each week with Jacoby Brissett. Brissett went 22-44 for 258 yards and two touchdowns, while Emari Demercado rushed four times for 64 yards. Trey McBride led the receivers with nine catches for 127 yards and one score in the loss. The Arizona defense recorded one sack and five tackles for loss in the game. Divisional games tend to favor the dog. The familiarity each team has leaves no surprises; just a game plan and execution.