Washington Nationals vs Baltimore Orioles Prediction, Preview and Odds - 06/27/2026

Game Time: 7:05 pm ET, Saturday, June 27, 2026

Venue:  Oriole Park at Camden Yards, Baltimore, MD

Where to Watch:  MLB TV

DraftKings:  Moneyline odds:  Nationals +100, Orioles -120; Over/Under:  9 runs

Bet365:  Moneyline odds:  Nationals +100, Orioles -120; Over/Under:  9 runs

BetMGM:  Moneyline odds:  Nationals +100, Orioles -115; Over/Under:  9 runs

Washington Nationals:  41-41 (4th place, NL East)

Baltimore Orioles:  38-44 (4th place, AL East)

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Washington Nationals:  4-6 last 10

Baltimore Orioles:  4-6 last 10

The Nationals are entering this series off a loss and lost their 4-game series against the Philadelphia Phillies 3-1 in their last series. They enter this game with a 41-41 record overall and have a road record of 24-16. This is the 2nd game of a 3-game series with the Orioles on Saturday with the series opener still to be played on Friday. Their offense ranks 4th in the MLB with a .744 OPS. Andrew Alvarez is their starting pitcher on Friday while Foster Griffin is making his start in this game on Saturday. He is 8-2 with a 3.15 ERA this season. His team won their last 2 straight games this season with him making an appearance. In his last MLB regular season appearance, he allowed 1 ER, 1 HR, and 0 BB with 9 SO on 4 hits through 7.1 IP against the Philadelphia Phillies.

The Orioles are entering this series off a loss and lost their 3-game series against the Los Angeles Angels 2-1 in their last series. They enter this game with a 38-44 record overall and have a home record of 22-19. This is the 2nd game of a 3-game series with the Nationals on Saturday with the 1st game of this series still to be played on Friday. Their offense ranks 16th in the MLB with a .722 OPS. Trevor Rogers is their starting pitcher on Friday while Brandon Young is making his start in this game on Saturday. He is 6-2 with a 3.07 ERA this season. His team won 8 of their last 9 games this season with him making an appearance. In his last MLB regular season start, he allowed 1 earned run, 0 homers, and 2 walks with 5 strikeouts on 5 hits through 5 innings pitched against the Los Angeles Dodgers.

The current betting odds have the Orioles listed as a slight favorite in this game according to Draftkings Sportsbook. The Nationals have looked good in their games this season with their 41-41 record overall, but that record has them right near the bottom of the NL East. They have been a better road team though with their 24-16 road record this year. Meanwhile, the Oriols haven't looked good in their games this season with their 38-44 record overall which has them right near the bottom of the AL East. They have looked a lot better in their own ballpark though with their 22-19 home record this season. The Nationals are going with Griffin in this one and he has looked good this season. He is 8-2 with a 3.15 ERA and the team has been having success with him lately. They have won 2 games in a row now with him starting and he is coming off another great start in which he gave up 1 earned run, but the bullpen has been a big issue for the Nationals this season and lately they have been blowing a ton of games. The Nationals do have one of the best offenses in MLB to lean on here, but the Orioles don't have a bad offense either and lately they have been putting up more runs. The Orioles are going with Young in this one and he has looked good this season too. He is 6-2 with a 3.07 ERA and his team has been having a ton of success with him lately. They have won 8 of their last 9 games with him starting and he is coming off another great start in which he only gave up 1 earned run which has been a common theme for him. Both of these starters have been solid, but Young has the edge at home with this Orioles offense starting to get hot lately, and the Nationals bullpen is going to be a big liability too. The best way to place a bet here is on the Orioles to win this game. 

Nationals Orioles Prediction:  Our MLB Pick for Saturday, June 27, 2026 (7:05 pm ET start time) is Orioles 7 Nationals 4.

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Washington Nationals: 178-229 (+6.1 units) on the moneyline in all games. 90-111 (+23.4 units) on the moneyline in road games. 141-188 (+19.8 units) on the moneyline as an underdog of +100 or higher. 24-15 UNDER against AL East opponents.

Baltimore Orioles: 19-21 (-5.3 units) on the moneyline against NL East opponents. 204-204 (-22.4 units) on the moneyline in all games. 105-99 (-23.5 units) on the moneyline in home games. 10-4 UNDER vs. a starting pitcher whose winning percentage is better than 70%.

Washington Nationals:  C. Abrams (SS) Day To Day - Side. M. Kranick (RP) Sixty Day IL - Elbow. J. Irvin (SP) Fifteen Day IL - Shoulder. K. Waldichuk (SP) Sixty Day IL - Forearm. J. Gray (SP) Sixty Day IL - Elbow. D. Herz (SP) Sixty Day IL - Elbow. T. Williams (SP) Sixty Day IL - Elbow.

Baltimore Orioles:  J. Holliday (2B) Day To Day - Groin. A. Rutschman (C) Seven Day IL - Concussion. C. Bassitt (SP) Fifteen Day IL - Back. D. Beavers (RF) Ten Day IL - Oblique. C. Povich (SP) Fifteen Day IL - Elbow. D. Kremer (SP) Sixty Day IL - Quad. R. Mountcastle (1B) Sixty Day IL - Foot. Y. Hiraldo (RP) Sixty Day IL - Shoulder. Z. Eflin (SP) Sixty Day IL - Elbow. J. Westburg (3B) Sixty Day IL - UCL. F. Bautista (RP) Sixty Day IL - Shoulder. C. Selby (SP) Sixty Day IL - Shoulder.

"He was stubborn to an approach, to a plan. He didn't chase. We tried to get him out of the zone there, but he's not going to do that. When he got a pitch in the zone, he stayed through it and went the other way and hit a ball really well." - Blake Butera on Bryce Harper after his team’s loss against the Phillies in their game on Thursday.

“Defense in general. We didn’t help ourselves at all, three errors today and we also had seven walks. That’s not a good recipe to win baseball games.” - Craig Albernaz after his team’s loss against the LA Angels in their game on Wednesday. 

James Wood (L) DH

Curtis Mead (R) 3B

Andrés Chaparro (R) 1B

Dylan Crews (R) RF

Daylen Lile (L) LF

Jacob Young (R) CF

Nasim Nuñez (S) SS

Jorbit Vivas (L) 2B

Keibert Ruiz (S) C

Taylor Ward (R) LF

Gunnar Henderson (L) SS

Leody Taveras (S) RF

Pete Alonso (R) 1B

Samuel Basallo (L) C

Colton Cowser (L) CF

Coby Mayo (R) DH

Jeremiah Jackson (R) 2B

Blaze Alexander (R) 3B

Batting Average:  CJ Abrams (.286)

Hits:  CJ Abrams (83)

Home Runs:  James Wood (20)

RBI:  CJ Abrams (57)

Stolen Bases:  Nasim Nuñez (31)

Wins:  Foster Griffin (8)

Saves:  Gus Varland (6)

ERA:  Julian Fernández (2.25)

Batting Average:  Blaze Alexander (.305)

Hits:  Pete Alonso (78)

Home Runs:  Pete Alonso (18)

RBI:  Pete Alonso (55)

Stolen Bases:  Leody Taveras (9)

Wins:  Brandon Young (6)

Saves:  Ryan Helsley (7)

ERA:  Jose Espada (0.00)

Managers:

Washington Nationals: Blake Butera (1st season)

Baltimore Orioles: Craig Albernaz (1st season)