USC Trojans vs Notre Dame Fighting Irish Game Preview and Prediction - 10/23/2021

by Amedeus Mastrangelo

Game Time: 7:30 pm ET, Saturday, October 23, 2021
Venue:  Notre Dame Stadium, Notre Dame, IN
Where to Watch:  NBC

 

Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  USC +3, ND -3; Over/Under:  58 points
Bet365:  Point Spread:  USC +3, ND -3; Over/Under:  58 points
BetMGM:  Point Spread:  USC +3, ND -3; Over/Under:  58 points
 

Season Record

USC Trojans:  3-3 (4th place, Pac-12 South)
Notre Dame Fighting Irish:  5-1 (1st place, FBS Independents)
 
Do not miss out on our expert handicapper analysis! Ben Burns is on a run of 11-1 (10*) PLAYS! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.

 

USC Trojans vs Notre Dame Fighting Irish Preview and Analysis

 
Recent Form
USC Trojans:  lost at home on Oct. 9 against the Utah Utes 42-26.
Notre Dame Fighting Irish:  won on the road on Oct. 9 against the Virginia Tech Hokies 32-29.
 
 
 

USC Trojans Analysis

USC is coming into this game with a 3-3 record overall and they are 2-0 in their road games this season where they will be in this game. They have put themselves in a very bad position with a 2-3 record in their conference games this season but they are getting a break here with this non-conference matchup. They have lost 2 of their last 3 games coming into this one, their last loss coming in their last game against Utah. Utah pretty much led that game from start to finish giving USC no chance to even make it a close game. Kedon Slovis played alright in that game as he completed 33/53 passes for 401 yards, 2 touchdowns and 1 interception. Keaontay Ingram led the team in rushing with 70 yards on 14 carries but their run game was not that strong in that one. Drake London had a very nice day as he led the receivers with 162 yards and 1 touchdown on 16 receptions while Gary Bryant Jr. also played well with 85 yards on 5 receptions. Kana'i Mauga led the defense with 8 solo tackles and 3 assisted ones in that game. Korey Foreman led the defense in sacks with 1.5 but no one on the defense was able to come away with an interception in that one. They have scored 193 points in their first 6 games averaging 32.2 PPG and they have allowed their opponents to score 164 points against them allowing 27.3 PPG. Their offense is averaging 448.2 YPG while their defense is allowing 382.2 YPG.
 
 

Notre Dame Fighting Irish Analysis

Notre Dame is coming into this game with a 5-1 record overall and they are 2-1 in their home games this season where they will be in this game. They suffered their first loss of the season to the Cincinnati Bearcats but they followed that up with a win over VT in their last game getting back on track. That game was a back and forth one that Notre Dame had to fight in the whole time but eventually came away with the 3 point win over VT. Jack Coan played alright in that game as he completed 9/12 passes for 108 yards and 1 touchdown while Tyler Buchner struggled at the quarterback position completing 6/14 passes for 113 yards, 1 touchdown and 2 interceptions. Kyren Williams led the team in rushing with 81 yards and 1 touchdown on 19 carries. Kevin Austin led the receivers with 70 yards on 3 receptions while Avery Davis was right behind him with 64 yards and 1 touchdown on 3 receptions. Clarence Lewis led the defense with 6 solo tackles while JD Bertrand was right behind with 5 solo tackles and 5 assisted ones. Isaiah Foskey recorded the only sack for them in that game while TaRiq Bracy came away with the only interception. They have scored 186 points in their first 6 games averaging 31 PPG and they have allowed their opponents to score 146 points against them allowing 24.3 PPG. Their offense is averaging 366.7 YPG while their defense is allowing 360.7 YPG.
 

 

USC vs Notre Dame Prediction

Notre Dame is coming into this game as a 3 point favorite with the current betting odds according to Draftkings Sportsbook. USC has not been having a good year working under their interim head coach after firing their head coach very early in the season. Notre Dame has a very good defense and has not been allowing many points in their games while their offense is starting to run more smoothly in their games. The best bet to place in this game is on Notre Dame to cover the spread here as they are the better team and are trending in the right direction this season while USC is moving the opposite way.
 
USC Notre Dame Prediction:  Our NCAAF Pick for Saturday, October 23, 2021 (7:30 pm ET start time) is ND 35 USC 17.
Don't miss our champion handicappers free picks and expert football picks today.  And if you enjoyed this USC Trojans Notre Dame Fighting Irish prediction, be sure to drop by every day for our weekly NCAAF predictions and previews.
 

NCAAF Betting Trends

 
USC Trojans: 15-22 O/U as an underdog of 3.5 to 10 points. 157-177 O/U in all games. 38-43 O/U when the total is between 56.5 and 63. 33-38 O/U as an underdog. 21-28 O/U as a road underdog. 70-78 O/U in road games. 
Notre Dame Fighting Irish: 156-175 O/U in all games. 27-34 O/U when the total is between 56.5 and 63. 109-113 O/U as a favorite. 65-75 O/U as a home favorite. 79-88 O/U in home games. 28-39 O/U against Pac Twelve conference opponents.
 

Key Injuries

 
USC Trojans:  M. Trigg (TE) Out Sat - Leg injury. S. Tuliaupupu (LB) Ques Sat - Knee injury. F. Martin II (OL) Ques Sat - Academics.
Notre Dame Fighting Irish:  M. Mayer (TE) Prob Sat - Undisclosed injury. M. Carmody (OL) Ques Sat - Ankle injury. T. Baker (OL) Ques Sat - Undisclosed injury.
 

Players to Watch

 
USC Trojans: Drake London is one player to watch in this contest. He leads his team in receiving yards and in touchdowns scored this season. He is coming off of a massive game where he led the team in receiving and had over 150 yards as well. He is one of their biggest playmakers and they will need him to play well here to win this game so look for them to give him a lot of looks in this game as they did in their last game.
 
Notre Dame Fighting Irish: Kyren Williams is one player to watch here. He leads his team in rushing yards and in touchdowns scored this season. He is coming off of a game where he led the team in rushing but did not get over the 100 yard mark in that game. They will need to control the run game in this one so look for him to get a lot of touches in this one as they look to do that.
 

Notable Quotes

 
“Shoot, all their games they’ve played about three [quarterbacks] every game. You have to be prepared because all of those guys are different challenges.” - Donte Williams on one of the challenges of going up against Notre Dame.
 
 
"I've been in a lot of games, coached in a lot of games, but I don't know that I've ever coached a group of guys that had such resolve and mental toughness, that regardless of the situation, they just kept playing. Unfazed by the circumstances." - Brian Kelly on his team’s performance in their win over VT in a very close game.
 
 

Starting Lineups

 
USC Trojans
WR London, Drake 
WR Tahj Washington
WR Trigg, Michael 
WR Gary Bryant Jr.
TE Krommenhoek, Erik 
QB Slovis, Kedon 
RB Ingram, Keaontay 
 
Notre Dame Fighting Irish
WR Austin Jr., Kevin 
WR Lenzy, Braden 
WR Davis, Avery 
TE Mayer, Michael 
QB Coan, Jack 
RB Williams, Kyren 
 

Statistical Leaders

 
USC Trojans
Passing: K. Slovis (1519)
Rushing: K. Ingram (419)
Receiving: D. London (832)
Touchdowns: D. London (5)
Sacks: D. Jackson (3)
Tackles: K. Mauga (23)
 
Notre Dame Fighting Irish
Passing: J. Coan (1208)
Rushing: K. Williams (363)
Receiving: M. Mayer (360)
Touchdowns: K. Williams (4)
Sacks: I. Foskey (5.5)
Tackles: J. Bertrand (37)
 
Coaches:
USC Trojans: Donte Williams (Interim)
Notre Dame Fighting Irish: Brian Kelly (12th season)
 

Weather Forecast

58 degrees F partly cloudy, 60% humidity, 0% chance of rain, up to 7 mph wind speeds W.


Amedeus Mastrangelo

About the Author:

Amedeus Mastrangelo has been heavily wagering on all sports for years and plays just about everything, including sides, totals, favorites, underdogs, against the spread, alternative spreads, first half, second half, player props, and futures. The bottom line is, if Mastrangelo can see an edge in any way shape or form, then he's going to take advantage.

All photographic images used for editorial content have been licensed from the Associated Press.

© 2021 Al McMordie's BigAl.com. All Rights Reserved.