by Rod Pearson
Monday, Nov 03, 2025
Game Time: 9:00 pm ET, Friday, November 7, 2025
Venue: Simmons Bank Liberty Stadium, Memphis, TN
Where to Watch: ESPN
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Tulane +6, Memphis -6; Over/Under: 55.5 points
Bet365: Point Spread: Tulane +6.5, Memphis -6.5; Over/Under: 55.5 points
BetMGM: Point Spread: Tulane +6.5, Memphis -6.5; Over/Under: 55.5 points
Season Record
Tulane Green Wave: 6-2 (3-1) (5th place, American)
Memphis Tigers: 8-1 (4-1) (2nd place, American)
Do not miss out on our expert handicapper analysis! Big Al McMordie is on a HOT STREAK in college football on a 14-6 CFB RUN for +$7,510 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.
Recent Form
Tulane Green Wave: lost their last game on the road against the UTSA Roadrunners 48-26.
Memphis Tigers: won their last game on the road against the Rice Owls 38-14.
Tulane Green Wave vs Memphis Tigers Preview and Analysis
Tulane is entering this game with a 6-2 record overall and they have a 3-1 record in their conference games too. They are 4-0 in their home games, 2-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against UTSA 48-26. Jake Retzlaff was the starting QB and he completed 14/28 passes for 194 passing yards, 1 touchdown, and 2 interceptions. Jake Retzlaff led the team in rushing yards with 63 and 1 TD. Omari Hayes led the receivers with 69 receiving yards on 3 receptions and 1 TD. Bailey Despanie led the defense in that game with 6 solo tackles and 3 assisted tackles while no one on the defense recorded a sack for them. No one on the defense came away with an interception for them in that one.
Memphis is entering this game with an 8-1 record overall and they have a 4-1 record in their conference games too. They are 4-0 in their home games, 4-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against Rice 38-14. Brendon Lewis was the starting QB and he completed 18/22 passes for 225 passing yards, 0 touchdowns, and 0 interceptions. Brendon Lewis led the team in rushing yards with 87 and 1 TD. Cortez Braham Jr. led the receivers with 66 receiving yards on 3 receptions. Chris Bracy led the defense in that game with 8 solo tackles and 2 assisted tackles while Pooda Walker and Jalen Bell each led the defense in sacks with 0.5. Omarion Cooper came away with the only interception for them in that one.
Tulane vs Memphis Prediction
The current betting odds have Memphis listed as a 6 point favorite in this game according to Draftkings Sportsbook. Memphis has looked great in their games this season with their 8-1 record overall and their 4-1 conference record which has them right near the top of the American Conference. They have looked great on their home field too with their 4-0 home record this season, and they are looking like the biggest threat to win their conference this year. Meanwhile, Tulane has looked really good in their games this season with their 6-2 record overall and their 3-1 conference record which has them in the top half of the American Conference. They were also a threat to win this conference this season, but they haven't looked as good lately and they haven't been a great road team this year with their 2-2 road record. Their only loss before last week was a road loss to Ole Miss who has been one of the best teams in the nation, but now they are off a 48-26 loss to UTSA in their last one and that loss was a big blow to their playoff hopes. Tulane can still make the playoffs, but they would have to win the conference and they need this win to get to the American Championship. Memphis also needs this win though and they will bring their best effort after a 38-14 rout over Rice in their last one. Memphis has better wins in the conference under their belt too and they also have the better defense to lean on. The best way to place a bet here is on Memphis to cover the spread in this game.
Tulane Memphis Prediction: Our NCAAF Pick for Friday, November 7, 2025 (9:00 pm ET start time) is Memphis 34 Tulane 24.
Don't miss our champion handicappers free picks and expert football picks today. And if you enjoyed this Tulane Green Wave Memphis Tigers prediction, be sure to drop by every day for our weekly NCAAF predictions and previews.
NCAAF Betting Trends
Tulane Green Wave: 1-5 ATS as an underdog. 3-6 ATS versus good rushing teams - averaging 4.75 rushing yards/carry or more. 3-9 ATS versus good offensive teams - averaging 5.9 yards/play or more. 12-6 UNDER against conference opponents. 11-4 UNDER after playing their last game on the road.
Memphis Tigers: 10-4 ATS after a win by 17 or more points. 17-10 ATS at home when playing against a top-level team (Win Pct. > 75%). 27-17 ATS at home versus good offensive teams - averaging 5.9 yards/play or more. 4-1 UNDER in a home game where the total is between 49.5 and 56.
Key Injuries
Tulane Green Wave: J. Lewis (CB) Questionable - Undisclosed. D. Jackson (CB) Questionable - Undisclosed. S. Howard (LB) Questionable - Undisclosed. C. Helmke (K) Questionable - Undisclosed. G. Mmahat (WR) Questionable - Undisclosed. T. Thompson (TE) Out - Knee. J. Tchienchou (S) Questionable - Undisclosed. D. Agu (LB) Out - Undisclosed.
Memphis Tigers: B. White (LB) Questionable - Undisclosed. C. Law (LB) Questionable - Undisclosed. C. Logan Jr. (CB) Questionable - Undisclosed. J. Thompson (CB) Questionable - Undisclosed. C. Miller (CB) Questionable - Undisclosed. C. Ross (TE) Questionable - Undisclosed. O. Castaneda (K) Out - Undisclosed. G. Troutman (QB) Out - Undisclosed. C. Law (LB) Out - Undisclosed. K. Marsh (CB) Out - Undisclosed.
Notable Quotes
“Starts with me. Ends with me. We got our butts kicked.” - Jon Sumrall after his team’s loss against UTSA in their last game.
“He had been dealing with a lower leg issue previously. We’ll monitor him day-to-day like any of the guys that were banged up tonight.” - Ryan Silverfield after his team’s win against Rice in their last game.
Starting Lineups
Tulane Green Wave
WR Preston, Shazz
WR Brown-Stephens, Anthony
WR Bohanon, Bryce
TE Pascuzzi, Johnny
QB Retzlaff, Jake
RB Gordon, Javin
Memphis Tigers
WR Braham Jr., Cortez
WR Bussey, Marcello
WR Hawkins, Jamari
TE Ross, Christian
QB Lewis, Brendon
RB Desrosiers Jr., Greg
Statistical Leaders
Tulane Green Wave
Passing: Jake Retzlaff (1,622)
Rushing: Jake Retzlaff (513)
Receiving: Omari Hayes (376)
Touchdowns: Jake Retzlaff (9)
Memphis Tigers
Passing: Brendon Lewis (1,869)
Rushing: Brendon Lewis (562)
Receiving: Cortez Braham Jr. (632)
Touchdowns: Brendon Lewis (8)
Coaches:
Tulane Green Wave: Jon Sumrall (2nd season)
Memphis Tigers: Ryan Silverfield (6th season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
