by Rod Pearson
Wednesday, Sep 16, 2026
Game Time: 7:00 pm ET, Saturday, September 19, 2026
Venue: Faurot Field at Memorial Stadium, Columbia, MO
Where to Watch: SECN+
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Troy +26.5, Mizzou -26.5; Over/Under: 49.5 points
Bet365: Point Spread: Troy +26.5, Mizzou -26.5; Over/Under: 49.5 points
BetMGM: Point Spread: Troy +26.5, Mizzou -26.5; Over/Under: 49.5 points
Season Record
Troy Trojans: 2-0 (0-0) (1st place, Sun Belt West)
Missouri Tigers: 2-0 (0-0) (2nd place, SEC)
Do not miss out on our expert handicapper analysis! Harry Gagnon is on a HOT STREAK in college football on an 8-3-2 CFB RUN for +$4,820 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.
Recent Form
Troy Trojans: won their last game at home against the Alabama State Hornets 34-17.
Missouri Tigers: won their last game on the road against the Kansas Jayhawks 38-21.
Troy Trojans vs Missouri Tigers Preview and Analysis
Troy is entering this game with a 2-0 record overall and they have a 0-0 record in their conference games too. They are 2-0 in their home games, 0-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against Alabama State 34-17. Will Crowder was the starting QB and he completed 14/27 passes for 201 passing yards, 1 touchdown, and 0 interceptions. Jaheim Merriweather led the team in rushing yards with 127 and 3 TDs. TK Keyes led the receivers with 119 receiving yards on 5 receptions and 1 TD. TJ Thompson and Keno Jones each led the defense in that game with 6 tackles while Keno Jones led the defense in sacks with 1.5. No one on the defense came away with an interception for them in that one.
Missouri is entering this game with a 2-0 record overall and they have a 0-0 record in their conference games too. They are 1-0 in their home games, 1-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against Kansas 38-21. Austin Simmons was the starting QB and he completed 19/29 passes for 292 passing yards, 3 touchdowns, and 0 interceptions. Jamal Roberts led the team in rushing yards with 125 and 1 TD. Donovan Olugbode led the receivers with 121 receiving yards on 6 receptions and 1 TD. Nicholas Rodriguez and Santana Banner each led the defense in that game with 6 tackles while Daeden Hopkins and Donta Simpson each led the defense in sacks with 1.5. Robert Woodyard Jr. and Jahlil Florence each came away with 1 interception for them in that one.
Troy vs Missouri Prediction
The current betting odds have Missouri listed as a 26.5 point favorite in this game according to Draftkings Sportsbook. Missouri has looked good in their games this season with their 2-0 record overall so far. They have looked good on their own home field too with their 1-0 home record this season. Meanwhile, Troy has looked good in their games this season with their 2-0 record overall so far. They haven't played in any road games yet and will be playing their 1st road game of the season here. Troy has been a solid team in the Sun Belt over the years, but they don't have a lot of talent this season and haven't looked good to start the season. They are coming off a win over a team from the FCS, beating Alabama State 34-17, and they gave up quite a few points considering the team they were playing. The offense looked good in the 1st half and the game was pretty much over by then, but they really didn't get much going in the 2nd half. They had a lot of trouble in their season opener too. They beat Sam Houston State at home 24-21 and had a lot of trouble with a program that has struggled a lot since making the jump to the FBS. Now they are facing a real team ranked inside the top 25 and it isn't the best opponent for them in their 1st road game of the year. Missouri is coming off an emphatic 38-21 win over Kansas on the road in their last one and their offense has looked great in both games this season. They also played that game on Friday night, so they have had an extra day to rest and will be looking to fine tune things here in their last game before conference play. Missouri has a talented team this season with a really good QB in Simmons and Troy's offense is going to have a lot of trouble keeping up in this game with the way they have looked this season. The best way to place a bet here is on Missouri to cover the spread in this game.
Troy Missouri Prediction: Our NCAAF Pick for Saturday, September 19, 2026 (7:00 pm ET start time) is Missouri 42 Troy 13.
Don't miss our champion handicappers free picks and expert football picks today. And if you enjoyed this Troy Trojans Missouri Tigers prediction, be sure to drop by every day for our weekly NCAAF predictions and previews.
NCAAF Betting Trends
Troy Trojans: 4-7 ATS in non-conference games. 0-3 ATS after a 2 game home stand. 13-4 UNDER when the total is between 49.5 and 56. 8-4 UNDER as a road underdog. 11-1 UNDER after playing a game at home.
Missouri Tigers: 14-6 ATS as a favorite. 9-4 ATS when the total is between 49.5 and 56. 7-3 ATS after scoring 37 points or more last game. 4-0 UNDER off a road win. 6-3 UNDER after playing their last game on the road.
Key Injuries
Troy Trojans: None.
Missouri Tigers: G. Hoffman (TE) Questionable - Undisclosed. J. Brady (WR) Questionable - Undisclosed. C. Green (OG) Questionable - Undisclosed. A. Hardy (RB) Out - Leg.
Notable Quotes
“When we started playing at a very high level last year on defense, we were very similar as to how this game went today. Elite in some aspects, playing at a high level in some aspects, and then a ball go through a gap or we misfit and it go for a 50 yard rushing touchdown.” - Gerad Parker after his team’s win against Alabama State in their last game.
“The things that we gave them were undisciplined penalties, special teams were not good tonight in any form or facet, but we overcame it and that's what you have to do on the road.” - Eli Drinkwitz after his team’s win against kansas in their last game.
Starting Lineups
Troy Trojans
WR Kinchen, Howard
WR White, Noreel
WR Boyd, Jywon
TE Worley, Jackson
QB Crowder, Goose
RB Lovett, Jordan
Missouri Tigers
WR Montgomery, Naeshaun
WR Goodie Sr., Caleb
WR Lee, Cayden
TE Norfleet, Brett
QB Simmons, Austin
RB Roberts, Jamal
Statistical Leaders
Troy Trojans
Passing: Goose Crowder (366)
Rushing: Jaheim Merriweather (149)
Receiving: TK Keyes (167)
Touchdowns: Jaheim Merriweather (3)
Missouri Tigers
Passing: Austin Simmons (544)
Rushing: Jamal Roberts (172)
Receiving: Donovan Olugbode (228)
Touchdowns: Donovan Olugbode (3)
Coaches:
Troy Trojans: Gerad Parker (3rd season)
Missouri Tigers: Eli Drinkwitz (7th season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
