Toronto Blue Jays vs Boston Red Sox Prediction, Preview and Odds - 06/28/2025

Game Time: 4:10 pm ET, Saturday, June 28, 2025

Venue:  Fenway Park, Boston, MA

Where to Watch:  Sportsnet, NESN

DraftKings:  Moneyline odds:  Blue Jays -126, Red Sox +104; Over/Under:  9 runs

Bet365:  Moneyline odds:  Blue Jays -125, Red Sox +105; Over/Under:  9 runs

BetMGM:  Moneyline odds:  Blue Jays -125, Red Sox +105; Over/Under:  9 runs

Toronto Blue Jays:  43-37 (3rd place, AL East)

Boston Red Sox:  40-42 (4th place, AL East)

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Toronto Blue Jays:  5-5 last 10

Boston Red Sox:  4-6 last 10

The Blue Jays are entering this series off a win and won their 3-game series against the Cleveland Guardians 2-1 in their last series. They enter this game with a 43-37 record overall and have a road record of 18-21. This is the 2nd game of a 3-game series with the Red Sox on Saturday with the series opener still to be played on Friday. Their offense ranks 12th in the MLB with a .723 OPS. José Berríos is their starting pitcher on Friday while Chris Bassitt is making his start in this game on Saturday. He is 7-3 with a 3.61 ERA this season. His team won 4 of their last 5 games this season with him making an appearance. In his last MLB regular season start, he allowed 1 ER, 0 HR, and 1 BB with 7 SO on 3 hits through 6 IP against the Chicago White Sox.

The Red Sox are entering this series off a loss and got swept in their 3-game series against the Los Angeles Angels 3-0 in their last series. They enter this game with a 40-42 record overall and have a home record of 22-17. This is the 2nd game of a 3-game series with the Blue Jays on Saturday with the 1st game of this series still to be played on Friday. Their offense ranks 7th in the MLB with a .732 OPS. Brayan Bello is their starting pitcher on Friday while Lucas Giolito is making his start in this game on Saturday. He is 3-1 with a 4.53 ERA this season. His team won 4 of their last 5 games this season with him making an appearance. In his last MLB regular season start, he allowed 2 earned runs, 2 homers, and 2 walks with 5 strikeouts on 4 hits through 6 innings pitched against the San Francisco Giants.

The current betting odds have the Blue Jays listed as a slight favorite in this game according to Draftkings Sportsbook. The Red Sox haven't looked great in their games this season with their 40-42 record overall which has them near the bottom of the AL East. They have looked a lot better in their own ballpark though with their 22-17 home record. Meanwhile, the Blue Jays have looked good in their games this season with their 43-37 record overall which has them right in the middle of the AL East. They haven't been a good road team though with their 18-21 road record this season. Neither team has really been rolling into this series lately, but the Blue Jays have been the slightly hotter team lately and can take advantage of this better pitching matchup. They are going with Bassitt in this one and he has looked good this season. He is 7-3 with a 3.61 ERA and the Blue Jays have had a lot of success with him starting all year. They have won 4 of the last 5 games that he started in and he is coming off another great start in which he only gave up 1 earned run, something that has been a common theme for him lately. The Red Sox are going with Giolito in this one and he hasn't looked great this year. He is 3-1 with a 4.53 ERA and has been giving up quite a few runs this year. He only gave up 2 earned runs in his last start and the team has won 4 of their last 5 games with him starting too, but he will struggle against this good Blue Jays offense, especially when he has had some really bad starts at home this year. The best way to place a bet here is on the Blue Jays to win this game. 

Blue Jays Red Sox Prediction:  Our MLB Pick for Saturday, June 28, 2025 (4:10 pm ET start time) is Blue Jays 6 Red Sox 3.

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Toronto Blue Jays: 205-200 (-24.9 units) on the moneyline in all games. 103-111 (-10.2 units) on the moneyline when the money line is +125 to -125. 52-74 (-29.3 units) on the moneyline against division opponents. 9-4 UNDER on the road vs. poor fielding teams - averaging 0.75+ errors/game.

Boston Red Sox: 74-73 (+6.5 units) on the moneyline vs. an AL starting pitcher whose WHIP is 1.300 or better. 64-52 (+20.3 units) on the moneyline vs. an AL starting pitcher whose ERA is 3.70 or better. 84-101 (+6.1 units) on the moneyline as an underdog of +100 or higher. 31-22 UNDER at home when the total is 8 to 8.5.

Toronto Blue Jays:  V. Guerrero Jr. (1B) Day To Day - Forerm. B. Francis (SP) Fifteen Day IL - Shoulder. D. Varsho (CF) Ten Day IL - Hamstring. A. Santander (RF) Ten Day IL - Shoulder. Y. Garcia (RP) Fifteen Day IL - Shoulder. R. Burr (RP) Sixty Day IL - Shoulder. A. Manoah (SP) Sixty Day IL - Elbow. A. Bastardo (SP) Sixty Day IL - Elbow.

Boston Red Sox:  H. Dobbins (SP) Fifteen Day IL - Elbow. J. Hicks (SP) Fifteen Day IL - Toe. J. Winckowski (RP) Sixty Day IL - Elbow. N. Burdi (RP) Fifteen Day IL - Knee. T. Casas (1B) Sixty Day IL - Knee. J. Slaten (RP) Fifteen Day IL - Shoulder. L. Hendriks (RP) Fifteen Day IL - Hip. A. Bregman (3B) Ten Day IL - Quad. M. Yoshida (LF) Sixty Day IL - Shoulder. K. Crawford (SP) Sixty Day IL - Knee. T. Houck (SP) Fifteen Day IL - Flexor. C. Murphy (RP) Sixty Day IL - Elbow. P. Sandoval (SP) Sixty Day IL - Elbow.

“I know they’re not trying to throw at Vlad, we’re not trying to throw at Hosey. Just kind of one of those things where you’re trying to make a pitch. I thought everyone handled it fine.” - John Schneider after his team’s win against the Guardians in their game on Thursday.

“It’s one of those that sucks, right? Because we were talking about how deep we were in Spring Training and the options that we had in the starting rotation, and now it’s getting thinner and thinner.” - Alex Cora after his team’s loss against the LA Angels in their game on Wednesday.

Bo Bichette (R) DH

Nathan Lukes (L) RF

Vladimir Guerrero Jr. (R) 1B

Addison Barger (L) 3B

Ernie Clement (R) SS

Andrés Giménez (L) 2B

Jonatan Clase (S) LF

Tyler Heineman (S) C

Myles Straw (R) CF

Rob Refsnyder (R) DH

Jarren Duran (L) LF

Romy Gonzalez (R) 1B

Carlos Narváez (R) C

Wilyer Abreu (L) RF

Trevor Story (R) SS

Ceddanne Rafaela (R) CF

Marcelo Mayer (L) 2B

Nate Eaton (R) 3B

Batting Average:  Tyler Heineman (.377)

Hits:  Bo Bichette (93)

Home Runs:  Bo Bichette (11)

RBI:  Bo Bichette (48)

Stolen Bases:  Andrés Giménez (9)

Wins:  Chris Bassitt (7)

Saves:  Jeff Hoffman (17)

ERA:  Justin Bruihl (0.00)

Batting Average:  Nate Eaton (.500)

Hits:  Jarren Duran (87)

Home Runs:  Wilyer Abreu (13)

RBI:  Trevor Story (41)

Stolen Bases:  Jarren Duran (15)

Wins:  Garrett Crochet (7)

Saves:  Aroldis Chapman (14)

ERA:  Nick Burdi (0.00)

Managers:

Toronto Blue Jays: John Schneider (4th season)

Boston Red Sox: Álex Cora (5th season)