Texas Rangers vs New York Yankees Prediction, Preview and Odds - 05/21/2025

Game Time: 7:05 pm ET, Wednesday, May 21, 2025

Venue:  Yankee Stadium, Bronx, NY

Where to Watch:  Prime Video

DraftKings:  Moneyline odds:  Rangers -105, Yankees -115; Over/Under:  7.5 runs

Bet365:  Moneyline odds:  Rangers -105, Yankees -115; Over/Under:  7.5 runs

BetMGM:  Moneyline odds:  Rangers -105, Yankees -115; Over/Under:  7.5 runs

Texas Rangers:  25-23 (3rd place, AL West)

New York Yankees:  27-19 (1st place, AL East)

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Texas Rangers:  7-3 last 10

New York Yankees:  7-3 last 10

The Rangers are entering this series off a loss and split their 4-game series against the Houston Astros 2-2 in their last series. They enter this game with a 25-23 record overall and have a road record of 8-13. This is the 2nd game of a 3-game series with the Yankees on Wednesday with the series opener still to be played on Tuesday. Their offense ranks 26th in the MLB with a .657 OPS. Patrick Corbin is their starting pitcher on Tuesday while Jacob deGrom is making his start in this game on Wednesday. He is 4-1 with a 2.29 ERA this season. His team won their last 4 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 0 ER, 0 HR, and 1 BB with 7 Ks on 5 hits through 8 IP against the Houston Astros.

The Yankees are entering this series off a win and won their 3-game series against the New York Mets 2-1 in their last series. They enter this game with a 27-19 record overall and have a home record of 15-9. This is the 2nd game of a 3-game series with the Rangers on Wednesday with the 1st game still to be played on Tuesday. Their offense ranks 1st in the MLB with a .822 OPS. Will Warren is their starting pitcher on Tuesday while Ryan Yarbrough is making his start in this game on Wednesday. He is 1-0 with a 3.70 ERA this season. His team lost 3 of their last 4 games this season with him making an appearance. In his last MLB regular season start, he allowed 2 earned runs, 1 homer, and 1 BB with 2 strikeouts on 6 hits through 5 innings played against the Athletics.

The current betting odds have the Rangers listed as a slight underdog in this game according to Draftkings Sportsbook. The Rangers have looked good in their games this season with their 25-23 record overall, but that record has them near the bottom of their division with some work to do. They haven't been a great road team this season either with their 8-13 road record, but they have looked a lot better in their games lately. Meanwhile, the Yankees have looked really good in their games this season with their 27-19 record overall which has them right at the top of their division, but they are also the only team in their division that is above .500. They have looked better in their own ballpark this year with their 15-9 home record, but they aren't going to have the better pitching matchup here. Both of these teams have been hot lately as both are 7-3 in their last 10 games respectively so the Rangers do have some momentum coming into this series. They are going to have deGrom on the mound too and he has looked great this season, going 4-1 with a 2.29 ERA. He didn't give up any runs in his last start either and the team has had a lot of success with him too, winning their last 4 games that he started in. Yarbrough is on the mound for the Yankees and he has been good this season as he is 1-0 with a 3.70 ERA, but he hasn't been nearly as reliable as deGrom has been throughout his career. The Rangers are always going to have a chance with deGrom on the mound and now that they are starting to get hot and have looked a lot better in their games lately, this will be the best chance the Rangers have to win a game on the road in this series. The best way to place a bet here is on the Rangers to win this game. 

Rangers Yankees Prediction:  Our MLB Pick for Wednesday, May 21, 2025 (7:05 pm ET start time) is Rangers 3 Yankees 2.

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Texas Rangers: 57-85 (-13.6 units) on the moneyline as an underdog of +100 or higher. 92-101 (-9.4 units) on the moneyline in road games. 135-140 (-13.8 units) on the moneyline vs. a team with a good bullpen whose WHIP is 1.350 or better. 35-23 OVER vs. AL teams scoring 4.9 or more runs/game on the season.

New York Yankees: 44-27 (+8.7 units) on the moneyline against AL West opponents. 171-129 (+14.4 units) on the moneyline against right-handed starters. 113-92 (+12.2 units) on the moneyline when playing against a team  with a winning record. 25-15 OVER at home when the money line is +125 to -125.

Texas Rangers:  C. Martin (RP) Day To Day - Shoulder. E. Carter (CF) Ten Day IL - Undisclosed. C. Seager (SS) Ten Day IL - Hamstring. K. Rocker (SP) Fifteen Day IL - Shoulder. C. Bradford (RP) Sixty Day IL - Elbow. J. Gray (SP) Sixty Day IL - Wrist. J. Sborz (RP) Sixty Day IL - Shoulder.

New York Yankees:  O. Cabrera (3B) Ten Day IL - Ankle. J. Chisholm Jr. (2B) Ten Day IL - Side. G. Stanton (DH) Sixty Day IL - Elbow. M. Stroman (SP) Fifteen Day IL - Knee. J. Brubaker (SP) Sixty Day IL - Ribs. J. Cousins (RP) Sixty Day IL - Elbow. L. Gil (SP) Sixty Day IL - Back. G. Cole (SP) Sixty Day IL - Elbow.

“Things were going well, trusting Jonah [Heim] behind the plate, trusting the game plan and trusting the defense behind me. It started to feel a little bit special when you’re missing middle and they’re hitting it hard right at guys, kind of the luck is on your side early on. Obviously, it ran out a little bit at the end of the outing, but it was a fun one.” - Jack Leiter after their loss against the Astros in their game on Sunday.

“It was definitely exciting. It was intense. Series that feel like playoff series are always good, especially early in the year. It preps you for the kind of baseball you want to play towards the end.” - Max Fried after their win against the Mets in their game on Sunday. 

Sam Haggerty (S) CF

Wyatt Langford (R) LF

Josh Jung (R) 3B

Adolis García (R) DH

Marcus Semien (R) 2B

Jonah Heim (S) C

Jake Burger (R) 1B

Kevin Pillar (R) RF

Ezequiel Duran (R) SS

Paul Goldschmidt (R) 1B

Trent Grisham (L) CF

Aaron Judge (R) RF

Cody Bellinger (L) LF

Anthony Volpe (R) SS

Jasson Domínguez (S) DH

DJ LeMahieu (R) 2B

Austin Wells (L) C

Oswald Peraza (R) 3B

Batting Average:  Tucker Barnhart (.333)

Hits:  Josh Jung (40)

Home Runs:  Wyatt Langford (9)

RBI:  Adolis García (24)

Stolen Bases:  Wyatt Langford (9)

Wins:  Tyler Mahle (5)

Saves:  Luke Jackson (8)

ERA:  Cole Winn (0.00)

Batting Average:  Aaron Judge (.401)

Hits:  Aaron Judge (71)

Home Runs:  Aaron Judge (15)

RBI:  Aaron Judge (41)

Stolen Bases:  Anthony Volpe (7)

Wins:  Max Fried (6)

Saves:  Luke Weaver (5)

ERA:  Brent Headrick (0.00)

Managers:

Texas Rangers: Bruce Bochy (3rd season)

New York Yankees: Aaron Boone (8th season)