St Louis Cardinals vs Pittsburgh Pirates Prediction, Preview and Odds - 05/22/2022

by Amedeus Mastrangelo

Saturday, May 21, 2022
Game Time: 11:35 am ET, Sunday, May 22, 2022
Venue:  PNC Park, Pittsburgh, PA 
Where to Watch:  Peacock

 

Opening Odds at USA Sportsbooks

DraftKings:  Moneyline odds:  Cardinals NL, Pirates NL; Over/Under:  NL runs
Bet365:  Moneyline odds:  Cardinals NL, Pirates NL; Over/Under:  NL runs
BetMGM:  Moneyline odds:  Cardinals NL, Pirates NL; Over/Under:  NL runs
 

Season Record

St Louis Cardinals:  21-18 (2nd place, NL Central)
Pittsburgh Pirates:  16-22 (3rd place, NL Central)
 
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St Louis Cardinals vs Pittsburgh Pirates Preview and Analysis

 
Recent Form
St Louis Cardinals:  5-5 last 10
Pittsburgh Pirates:  4-6 last 10
 
 
 

St Louis Cardinals Analysis

The Cardinals are coming into this game with a 21-18 record overall and they are 11-10 in their road games this season where they will be in this game. They have lost 2 of their last 3 games but are coming into this one off of a win in their last game which snapped a 2 game losing streak that they were on. They just lost their 4-game series against the New York Mets 3-1 and they are playing the series finale of a 3-game series with the Pirates on Sunday. This will be the 3rd game of the series on Sunday with the 2nd game still to be played on Saturday. Rookie pitcher Matthew Liberatore is the starting pitcher for them on Saturday while Steven Matz is on the mound for them here on Sunday. He is 3-3 with a 6.03 ERA this season. His team lost 2 of their last 3 games this season with him as a starter. In his last start, he allowed 2 earned runs, 2 homers, and 0 BB with 7 strikeouts on 3 hits in 5 innings played against the New York Mets. They scored 15 runs in their last series averaging just under 4 runs scored per game in that span and they allowed 24 runs against them averaging 6 runs allowed per game.
 

Pittsburgh Pirates Analysis

The Pirates are coming into this game with a 16-22 record overall and they are 9-11 in their home games this season where they will be in this game. They have lost 3 of their last 4 games and are coming into this one off of a loss in their last game. They just lost their 3-game series against the Chicago Cubs 2-1 and they are playing the series finale of a 3-game series with the Cardinals on Sunday. This will be the 3rd game of the series on Sunday with the 2nd game still to be played on Saturday. José Quintana is the starting pitcher for them on Saturday while Bryse Wilson will be on the mound for them here on Sunday. He is 0-2 with a 5.67 ERA this season. His team lost their last 4 straight games this season with him as a starter. In his last start, he allowed 3 earned runs, 1 homer, and 2 BB with 2 strikeouts on 8 hits in 5.1 innings played against the Chicago Cubs. They scored 3 runs in their last series averaging 1 run scored per game in that span and they allowed 18 runs against them averaging 6 runs allowed per game.
 

 

Cardinals vs Pirates Prediction

The Pirates are coming into this game not playing very well recently but they have come close in their games with the Cardinals and they will likely not get swept at home here as the Cardinals have not been playing that great themselves. Matz is starting for the Cardinals here and he has not been great in his starts this season. Bryse has not been great for the Pirates either but he has been pitching better and more consistently than Matz has and the Pirates have been hitting the ball well in this series. They will likely get a win at home here with the cardinals not playing that great in their recent games. The best bet here is on the Pirates to win this game.
 
Cardinals Pirates Prediction:  Our MLB Pick for Sunday, May 22, 2022 (11:35 am ET start time) is Pirates 5 Cardinals 3.
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MLB Betting Trends

 
St Louis Cardinals: 142-121 (+15.6 Units) ML in all games. 72-62 (+19.1 Units) ML in road games. 13-8 UNDER in road games.
Pittsburgh Pirates: 96-164 (-24.5 Units) ML in all games. 24-51 (-15.7 Units) ML against left-handed starters. 28-11 UNDER after 6 consecutive games versus division rivals.
 

Key Injuries

 
St Louis Cardinals:  A. Knizner (C) Ques Sat - Concussion. E. Sosa (SS) Ques Sat - Ankle. T. O'Neill (RF) Mid June - Shoulder.
Pittsburgh Pirates:  J. Marisnick (CF) Mid July - Thumb. K. Newman (SS) Early June - Groin. G. Allen (CF) Out indefinitely - Hamstring.
 
 

Notable Quotes

 
"It was good to get him back out there. I talked to him during batting practice, and I could tell he really wanted to pitch. I knew he would bounce back." - Oliver Marmol after his team’s win against the Pirates on Friday.
 
 
"I think in order to talk about how (Wainwright) pitches, I think you've got to acknowledge how Yadi calls the game and how well they work together. They've been doing it for something like 40 years, so there are times where it almost seems like they're not even calling pitches. It seems like they're just on the same page and they roll through it. It's cool to watch it." - Michael Chavis on Wainwright after their loss against the Cardinals on Friday.
 
 

Starting Lineups

 
St Louis Cardinals
Tommy Edman (S) SS
Brendan Donovan (L) DH
Paul Goldschmidt (R) 1B
Nolan Arenado (R) 3B
Juan Yepez (R) LF
Nolan Gorman (L) 2B
Dylan Carlson (S) RF
Yadier Molina (R) C
Harrison Bader (R) CF
 
Pittsburgh Pirates
Ben Gamel (L) LF
Ke'Bryan Hayes (R) 3B
Bryan Reynolds (S) CF
Yoshi Tsutsugo (L) DH
Josh VanMeter (L) 2B
Michael Chavis (R) 1B
Jack Suwinski (L) RF
Michael Perez (L) C
Rodolfo Castro (S) SS
 

Statistical Leaders

 
St Louis Cardinals
Batting Average:  Nolan Gorman (.333)
Hits:  Paul Goldschmidt (48)
Home Runs:  Nolan Arenado (9)
RBI:  Nolan Arenado (31)
Stolen Bases:  Harrison Bader (11)
Wins:  Adam Wainwright (5)
Saves:  Giovanny Gallegos (8)
ERA:  Ryan Helsley (0.00)
 
Pittsburgh Pirates
Batting Average:  Tucupita Marcano (.500)
Hits:  Ke'Bryan Hayes (36)
Home Runs:  Daniel Vogelbach (6)
RBI:  Ben Gamel (15)
Stolen Bases:  Ke'Bryan Hayes (4)
Wins:  Dillon Peters (3)
Saves:  David Bednar (8)
ERA:  Max Kranick (0.00)
 
Managers:
St Louis Cardinals: Oliver Marmol (1st season)
Pittsburgh Pirates: Derek Shelton (3rd season)


Amedeus Mastrangelo

About the Author:

Amedeus Mastrangelo has been heavily wagering on all sports for years and plays just about everything, including sides, totals, favorites, underdogs, against the spread, alternative spreads, first half, second half, player props, and futures. The bottom line is, if Mastrangelo can see an edge in any way shape or form, then he's going to take advantage.

All photographic images used for editorial content have been licensed from the Associated Press.

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