St John's Red Storm vs Duke Blue Devils Prediction, Picks and Game Preview - 03/27/2026

Game Time: 7:10 pm ET, Friday, March 27, 2026

Venue:  Capital One Arena, Washington, DC

Where to Watch:  CBS

DraftKings:  Point Spread:  St John’s +6.5, Duke -6.5; Over/Under:  141.5 points

Bet365:  Point Spread:  St John’s +6.5, Duke -6.5; Over/Under:  141.5 points

BetMGM:  Point Spread:  St John’s +6.5, Duke -6.5; Over/Under:  142.5 points

St John's Red Storm:  30-6 (18-2) (1st place, Big East)

Duke Blue Devils:  34-2 (17-1) (1st place, ACC)

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St John's Red Storm:  5-0  last 5

Duke Blue Devils:  5-0  last 5

St John’s is entering this game with a 30-6 record overall, an 18-2 record in conference games, and they are 6-3 in their neutral site games this season where they will be in this game. They are coming off a win against the Kansas Jayhawks in their last game. Zuby Ejiofor and Bryce Hopkins each led the team in points in that game with 18 while Ian Jackson was next on the team with 10. Zuby Ejiofor and Dylan Darling each led the team in assists with 4 in that game while Zuby Ejiofor and Dillon Mitchell each led the team in rebounds with 9. They were 36.2% from the field, 31.4% from 3-point range, and 54.5% from the free throw line with their shooting in that game. Their offense is averaging 81.1 PPG and their defense is allowing their opponents to average 69.4 PPG against them. St John’s has an ATS record of 21-13-1 this season and their O/U record is 12-23.

Duke is entering this game with a 34-2 record overall, a 17-1 conference record, and they are 9-1 in their neutral site games this season where they will be in this game. They are coming off a win against the TCU Horned Frogs in their last game. Cameron Boozer led the team in points in that game with 19 while Isaiah Evans was next on the team with 17. Cayden Boozer led the team in assists with 5 in that game while Cameron Boozer led the team in rebounds with 11. They were 55.1% from the field, 33.3% from 3-point range, and 87% from the free throw line with their shooting in that game. Their offense is averaging 81.9 PPG and their defense is allowing their opponents to average 63.1 PPG against them. Duke has an ATS record of 20-16 this season and their O/U record is 12-24.

The current betting odds have Duke listed as a 6.5 point favorite in this game according to Draftkings Sportsbook. Duke has looked great in their games this season with their 34-2 record overall and their 17-1 conference record which had them right at the top of the ACC. They have looked great in their neutral site games too with their 9-1 record in those. Meanwhile, St John's has looked really good in their games this season with their 30-6 record overall and their 18-2 conference record which had them right at the top of the Big East. They are also 6-3 in their neutral site games this season. St John's has been rolling lately with 8 wins in a row now. They aren't the highest seeded Big East team in the tournament, but they won the regular season and the Big East Tournament, proving themselves as the best team in the conference. They are off a win over Kansas in their last one and that wasn't an easy win for them, but they did struggle late in that game. They had a really big lead by double digits with a few minutes left and they let Kansas back into the game, needing a buzzer beater just to win the game by 2 points and avoid OT. Duke has also been rolling in their games lately with 13 wins in a row now and just like St John's did, Duke also won the ACC regular season and the ACC tournament. They had a bit of a scare in the 1st round with Siena as they pulled ahead late in that game but never really had control of the game. They looked a lot better in the last round though, crushing TCU after a close 1st half, and now they are going to be getting healthier for this game so this Duke team is only getting stronger at the right time. Duke has been one of the best teams in the nation all season and as good as St John's has looked lately, they don't have the talent to make a comeback if they fall behind early. Duke has been getting better in each game of the tournament and they will be looking to have a stronger start after their last 2 games, and that could spell trouble for St John's. The best way to place a bet here is on Duke to cover the spread in this game. 

St John's Duke Prediction:  Our NCAAB Pick for Friday, March 27, 2026 (7:10 pm ET start time) is Duke 81 St John’s 68.

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St John's Red Storm: 12-6 ATS as an underdog. 10-3 ATS when playing against a top-level team (Win Pct. > 80%). 28-13 ATS versus very good teams - outscoring their opponents by 8+ points/game. 9-5 UNDER after 3 or more consecutive unders. 4-0 UNDER in a post-season tournament game.

Duke Blue Devils: 3-6 ATS when playing against a top-level team (Win Pct. > 80%). 3-6 1H ATS as a neutral court favorite or pick. 19-9 UNDER in all neutral court games. 28-16 UNDER versus very good teams - outscoring their opponents by 8+ points/game. 

St John's Red Storm:  C. Pohto (G) Out - Hip. I. Suljanovic (F) Out - Knee.

Duke Blue Devils:  C. Foster (G) Questionable - Foot. I. Ufochukwu (C) Out - Undisclosed. S. Wilkins (G) Out - Redshirt.

“Bells [Dylan Darling] comes up to me and says, ‘Run “Power,’ which is a high back-screen pick-and-roll. I walked away thinking, ‘Wait a second, he hasn’t scored a bucket and he wants a play for himself?’ But then I thought, ‘He’s Bells.’ Not only did he do it, he did it with his right hand. I’m really proud of him, because to want the ball when you haven’t made a shot is unbelievable.” - Rick Pitino on the game winning shot in his team’s win against Kansas in the 2nd round of the NCAA Tournament on Sunday.

“TCU coming in, we knew how this would be a hard-fought game. I just keep coming back to the character of these guys. For Pat to come back to this game, was not easy by any means. He was fighting like crazy. He even came up to us before the first game, and just in the best interest of him, and ultimately our team also -- well, we always want him back out here, but we tried to get him ready for this game. That was pushing to begin with. But the fact that he's fighting to com back.” - Jon Scheyer after his team’s win against TCU in the Round of 32 of the NCAA Tournament on Saturday.

Z. Ejiofor 

B. Hopkins 

I. Jackson 

D. Mitchell 

O. Sellers

C. Boozer 

I. Evans 

C. Foster 

P. Ngongba 

D. Sarr

PPG: Zuby Ejiofor (16.3)

APG: Zuby Ejiofor (3.5)

Reb/G: Zuby Ejiofor (7.3)

PPG: Cameron Boozer (22.4)

APG: Cameron Boozer (4.2)

Reb/G: Cameron Boozer (10.3)

Coaches:

St John's Red Storm: Rick Pitino (3rd season)

Duke Blue Devils: Jon Scheyer (4th season)