by Rod Pearson
Friday, Nov 14, 2025
Game Time: 4:05 pm ET, Sunday, November 16, 2025
Venue: SoFi Stadium, Inglewood, CA
Where to Watch: FOX
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Seahawks +3.5, Rams -3.5; Over/Under: 48.5 points
Bet365: Point Spread: Seahawks +3, Rams -3; Over/Under: 48.5 points
BetMGM: Point Spread: Seahawks +3, Rams -3; Over/Under: 48.5 points
Season Record
Seattle Seahawks: 7-2 (1st place, NFC West)
Los Angeles Rams: 7-2 (2nd place, NFC West)
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Recent Form
Seattle Seahawks: won their last game at home against the Arizona Cardinals 44-22.
Los Angeles Rams: won their last game on the road against the San Francisco 49ers 42-26.
Seattle Seahawks vs Los Angeles Rams Preview and Analysis
The Seahawks are entering this game with a 7-2 record overall and they have a 2-1 record in their divisional games too. They are 3-2 in their home games, 4-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Arizona Cardinals 44-22. Sam Darnold was the starting QB and he completed 10/12 passes for 178 passing yards, 1 touchdown, and 1 interception. Zach Charbonnet led the team in rushing yards with 83 and 1 TD. Jaxon Smith-Njigba led the receivers with 93 receiving yards on 5 receptions and 1 TD. Tyrice Knight led the defense in that game with 6 solo tackles and 2 assisted tackles while Tyrice Knight led the defense in sacks with 2. No one on the defense came away with an interception for them in that one.
The Rams are entering this game with a 7-2 record overall and they have a 1-1 record in their divisional games too. They are 3-1 in their home games, 3-1 in their road games, and they are also 1-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the San Francisco 49ers 42-26. Matthew Stafford was the starting QB and he completed 24/36 passes for 280 passing yards, 4 touchdowns, and 0 interceptions. Kyren Williams led the team in rushing yards with 73 and 2 TDs. Davante Adams led the receivers with 77 receiving yards on 6 receptions and 1 TD. Quentin Lake led the defense in that game with 8 solo tackles and 3 assisted tackles while no one on the defense recorded a sack for them. Emmanuel Forbes Jr. came away with the only interception for them in that one.
Seahawks vs Rams Prediction
The current betting odds have the Rams listed as a 3.5 point favorite in this game according to Draftkings Sportsbook. The Rams have looked great in their games this season with their 7-2 record overall which has them right near the top of the NFC West with one of the best records in the entire NFL. They are off a 42-26 win over the 49ers in their last one and they have been rolling in their games lately with 4 wins in a row now. Meanwhile, the Seahawks have looked great in their games this season with their 7-2 record overall which has them right near the top of the NFC West with one of the best records in the entire NFL. They are off a 44-22 win over the Cardinals in their last one and they have been rolling in their games lately with 4 wins in a row now. These two teams look like two of the best teams in the NFL right now and this is going to be a big game since the winner will take the lead in the division for the time being. Both offenses have been rolling and both defenses have looked great as neither team is giving up many points. This is a really big game for Darnold though as he will be looking for revenge from what the Rams did to him on the Vikings in the playoffs last year, but that could get to him in this one. Sean McVay knows what to do to rattle Darnold in this offense, and the Rams still have the more reliable QB with Matt Stafford. The Rams have the edge at home with the better QB. The best way to place a bet here is on the Rams to cover the spread in this game.
Seahawks Rams Prediction: Our NFL Pick for Sunday, November 16, 2025 (4:05 pm ET start time) is Rams 31 Seahawks 24.
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NFL Betting Trends
Seattle Seahawks: 24-34 ATS after 3 or more consecutive wins against the spread. 28-36 ATS off a home win against a division rival. 43-62 ATS after a win by 14 or more points. 13-6 UNDER in games where the line is +3 to -3. 6-3 UNDER after scoring 30 points or more last game.
Los Angeles Rams: 28-16 ATS in all games. 17-7 ATS as a favorite. 10-4 ATS vs. good offensive teams - scoring 24 or more points/game. 8-2 UNDER as a home favorite of 7 points or less. 8-4 UNDER in a home game where the total is greater than or equal to 45.5.
Key Injuries
Seattle Seahawks: C. Kupp (WR) Injured - Hamstring. L. Williams (DL) Injured - Wrist. C. Bryant (S) Injured - NRI. C. White (WR) Injured - Abdomen. J. Jobe (CB) Injured - Concussion. J. Bobo (WR) Injured - Calf. E. Jones IV (LB) Injured - Knee. J. Smith-Njigba (WR) Injured - Rest. J. Sundell (C) Injured - Knee. A. Barner (TE) Injured - Calf. C. Haynes (OG) Injured - Pectoral. G. Zabel (OG) Injured - Heel. T. Horton (WR) Injured - Groin.
Los Angeles Rams: D. Adams (WR) Injured - Oblique. D. Williams (CB) Injured - Shoulder. K. Turner (DL) Injured - Back. J. Whittington (WR) Injured - Back.
Notable Quotes
“It’s not going to happen every time. When it does, you’re appreciative of the guys' effort.” - Mike Macdonald after his team’s win against the Cardinals in their last game.
“He’s just been in total command. It’s a continuation of a guy that really works his tail off throughout the course of the week. He uses the accumulation of knowledge and experience, and he’s just playing really confident. It looks like the game is really in slow motion to him right now.” - Sean McVay after his team’s win against the 49ers in their last game.
Starting Lineups
Seattle Seahawks
WR Smith-Njigba, Jaxon
WR Shaheed, Rashid
WR Kupp, Cooper
TE Barner, AJ
QB Darnold, Sam
RB Walker III, Kenneth
FB Ouzts, Robbie
Los Angeles Rams
WR Adams, Davante
WR Nacua, Puka
WR Smith, Xavier
TE Higbee, Tyler
QB Stafford, Matthew
RB Williams, Kyren
Statistical Leaders
Seattle Seahawks
Passing: Sam Darnold (2,262)
Rushing: Kenneth Walker III (539)
Receiving: Jaxon Smith-Njigba (1,041)
Touchdowns: Zach Charbonnet (6)
Los Angeles Rams
Passing: Matthew Stafford (2,427)
Rushing: Kyren Williams (659)
Receiving: Puka Nacua (775)
Touchdowns: Davante Adams (9)
Coaches:
Seattle Seahawks: Mike Macdonald (2nd season)
Los Angeles Rams: Sean McVay (9th season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
