Seattle Seahawks vs Denver Broncos Prediction, Preview and Odds - 10/15/2026

Game Time: 8:15 pm ET, Thursday, October 15, 2026

Venue:  Empower Field at Mile High, Denver, CO

Where to Watch:  Prime Video

DraftKings:  Point Spread:  Seahawks -3, Broncos +3; Over/Under:  40.5 points

Bet365:  Point Spread:  Seahawks -3, Broncos +3; Over/Under:  40.5 points

BetMGM:  Point Spread:  Seahawks -3, Broncos +3; Over/Under:  40.5 points

Seattle Seahawks:  3-2 (2nd place, NFC West)

Denver Broncos:  3-2 (2nd place, AFC West)

Do not miss out on our expert handicapper analysis! Matt Fargo is on a HOT STREAK in the NFL on a 22-9-2 NFL RUN for +$12,240 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.

Seattle Seahawks:  lost their last game at home against the San Francisco 49ers 32-29.

Denver Broncos:  won their last game on the road against the Los Angeles Chargers 23-17.

The Seahawks are entering this game with a 3-2 record overall and they have a 1-1 record in their divisional games too. They are 2-1 in their home games, 1-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the San Francisco 49ers 32-29. Sam Darnold was the starting QB and he completed 18/29 passes for 195 passing yards, 1 touchdown, and 2 interceptions. Emanuel Wilson led the team in rushing yards with 61 and 1 TD. Jaxon Smith-Njigba led the receivers with 102 receiving yards on 5 receptions and 1 TD. Ernest Jones IV led the defense in that game with 9 solo tackles while Byron Murphy II led the defense in sacks with 2. Nehemiah Pritchett came away with the only interception for them in that one.

 

 

 

The Broncos are entering this game with a 3-2 record overall and they have a 1-1 record in their divisional games too. They are 2-0 in their home games, 1-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Los Angeles Chargers 23-17. Bo Nix was the starting QB and he completed 16/27 passes for 123 passing yards, 1 touchdown, and 0 interceptions. J.K. Dobbins led the team in rushing yards with 68 and 1 TD. Evan Engram led the receivers with 55 receiving yards on 4 receptions. Justin Strnad led the defense in that game with 8 solo tackles while Nik Bonitto led the defense in sacks with 2. Brandon Jones came away with the only interception for them in that one.

The current betting odds have the Seahawks listed as a 3 point favorite in this game according to Draftkings Sportsbook. The Seahawks have looked good in their games this season with their 3-2 record overall which has them right near the top of the NFC West. They haven't been a great road team though with their 1-1 road record this year. Meanwhile, the Broncos have looked good in their games this season with their 3-2 record overall which has them right in the middle of the AFC West. They have looked great on their home field too with their 2-0 home record this season. The Broncos are coming off a 23-17 win over the Chargers in their last one and they once again pulled off a late comeback to win in the 4th quarter. That has been their identity going back to last season, but that isn't an ideal way to win games either. They are really up and down as a team and even with one of the best defenses in the NFL, the offense still hasn't been doing their part with Bo Nix having trouble this season. The Seahawks are coming off a 32-29 loss to the 49ers who are still undefeated this year and that was a big divisional loss too, so the Seahawks will be looking to bounce back on Thursday night. They still have one of the best defenses in the NFL that can go toe-to-toe with this Broncos defense and the Seahawks offense has also looked a lot better. They have been putting up a ton of points since that season opener against the Patriots, even scoring 29 in that loss to the 49ers, and their offense has been a lot more consistent which could be the deciding factor here. The best way to place a bet here is on the Seahawks to cover the spread in this game. 

Seahawks Broncos Prediction:  Our NFL Pick for Thursday, October 15, 2026 (8:15 pm ET start time) is Seahawks 23 Broncos 19.

Don't miss our champion handicappers free picks and expert football picks today. And if you enjoyed this Seattle Seahawks Denver Broncos prediction, be sure to drop by every day for our weekly NFL predictions and previews.

Seattle Seahawks: 2-7 ATS versus poor rushing defenses - allowing 4.5 rushing yards/carry or more. 5-10 ATS on the road off an upset loss to a division rival as a favorite. 49-83 1H ATS in a road game where the total is between 35.5 and 42 points. 6-3 UNDER as a road favorite of 7 points or less. 5-0 UNDER after a 2 game home stand.

Denver Broncos: 15-6 ATS in home games. 12-6 ATS in all games where the total is between 35.5 and 42 points. 9-5 ATS vs. good offensive teams - scoring 24 or more points/game. 12-6 UNDER after playing their last game on the road. 11-5 UNDER when playing against a team with a winning record.

Seattle Seahawks:  D. Lock (QB) Injured - Forearm D. Thomas (LB) Injured - Ankle. L. Williams (DL) Injured - Ankle. C. Surratt (LB) Injured - Calf. I. Charles (WR) Injured - Knee. Z. Charbonnet (RB) Injured - Knee. J. Smith-Njigba (WR) Injured - Ankle. G. Holani (RB) Injured - Ribs. B. Stephens (OG) Injured - Shoulder.

Denver Broncos:  B. Jones (S) Injured - Foot. B. Powers (OG) Injured - Biceps. S. Jones (DL) Injured - Shoulder. T. Hufanga (S) Injured - Ankle. R. Moss (CB) Injured - Ribs. P. Surtain II (CB) Injured - Ankle.

“We want to stay aggressive. We got to be able to execute our run game and hold onto the football.” - Mike Macdonald after his team’s loss against the 49ers in their last game. 

“There were some things that were good and then specifically staying on the field and just converting four or five more third downs. You know, just, I’ve got to be a little bit better, too.” - Sean Payton after his team’s win against the LA Chargers in their last game. 

WR Smith-Njigba, Jaxon

WR Shaheed, Rashid

WR Kupp, Cooper

TE Barner, AJ 

QB Darnold, Sam

RB Wilson, Emanuel

FB Russell, Brady

WR Sutton, Courtland

WR Waddle, Jaylen

WR Franklin, Troy

TE Engram, Evan

QB Nix, Bo

RB Dobbins, J.K.

FB Prentice, Adam

Passing: Sam Darnold (755)

Rushing: Emanuel Wilson (251)

Receiving: Jaxon Smith-Njigba (583)

Touchdowns: Jaxon Smith-Njigba (7)

Passing: Bo Nix (942)

Rushing: J.K. Dobbins (229)

Receiving: Jaylen Waddle (204)

Touchdowns: Nate Adkins (2)

Coaches:

Seattle Seahawks: Mike Macdonald (3rd season)

Denver Broncos: Sean Payton (4th season)