Seattle Mariners vs New York Yankees Prediction, Preview and Odds - 08/12/2026

Game Time: 7:00 pm ET, Wednesday, August 12, 2026

Venue:  Yankee Stadium, Bronx, NY 

Where to Watch:  ESPN

DraftKings:  Moneyline odds:  Mariners +104, Yankees -126; Over/Under:  9 runs

Bet365:  Moneyline odds:  Mariners +105, Yankees -125; Over/Under:  8.5 runs

BetMGM:  Moneyline odds:  Mariners +105, Yankees -125; Over/Under:  8.5 runs

Seattle Mariners:  56-63 (3rd place, AL West)

New York Yankees:  66-52 (2nd place, AL East)

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Seattle Mariners:  3-7 last 10

New York Yankees:  5-5 last 10

The Mariners are entering this series off a loss and got swept in their 3-game series against the Tampa Bay Rays 3-0 in their last series. They enter this game with a 56-63 record overall and have a road record of 23-34. This is the 2nd game of a 3-game series with the Yankees on Wednesday with the series opener still to be played on Tuesday. Their offense ranks 28th in the MLB with a .683 OPS. Bryan Woo is their starting pitcher on Tuesday while Bryce Miller is making his start in this game on Wednesday. He is 4-6 with a 3.08 ERA this season. His team lost their last 5 straight games this season with him making an appearance. In his last MLB regular season appearance, he allowed 4 ER, 1 HR, and 2 BB with 5 SO on 5 hits through 5 IP against the Detroit Tigers.

The Yankees are entering this series off a loss and won their 3-game series against the Atlanta Braves 2-1 in their last series. They enter this game with a 66-52 record overall and have a home record of 29-26. This is the 2nd game of a 3-game series with the Mariners on Wednesday with the 1st game of this series still to be played on Tuesday. Their offense ranks 15th in the MLB with a .720 OPS. Ryan Weathers is their starting pitcher on Tuesday while Will Warren is making his start in this game on Wednesday. He is 8-6 with a 4.18 ERA this season. His team lost 2 of their last 3 games this season with him making an appearance. In his last MLB regular season start, he allowed 3 earned runs, 0 homers, and 1 walk with 5 strikeouts on 7 hits through 5.1 innings pitched against the St Louis Cardinals.

The current betting odds have the Mariners listed as a slight underdog in this game according to Draftkings Sportsbook. The Yankees have looked really good in their games this season with their 66-52 record overall which has them right near the top of the AL East. They have looked good in their own ballpark too with their 29-26 home record this season. Meanwhile, the Mariners haven't looked good in their games this season with their 56-63 record overall which has them right in the middle of the AL West. They have been a terrible road team too with their 23-34 road record this year. The Mariners are 3-7 in their last 10 games and they haven't looked great lately, but the Yankees are only 5-5 in their last 10 games. The Mariners are in a bad slump, but they do have the better pitching matchup here and will be desperate to break out. The Mariners are going with Miller in this one and he has looked great this season. He is 4-6 with a 3.08 ERA and he hasn't been giving up many runs all season. He did give up 4 earned runs in his last start, but that hasn't been a common theme for him and the team will be looking to pick up a win with him after losing 5 games in a row now with him starting. The Yankees are going with Warren in this one and he hasn't looked great this season. He is 8-6 with a 4.18 ERA and he has been the weak link in this Yankees starting rotation. He is coming off another start giving up 3 earned runs which has been a common theme for him this year and his team has had some trouble with him lately too, losing 2 of their last 3 games with him starting. The Mariners are going to be desperate to break out of their slump and this is going to be their best chance to take a game in this series, so look for them to take advantage of this pitching matchup. The best way to place a bet here is on the Mariners to win this game. 

Mariners Yankees Prediction:  Our MLB Pick for Wednesday, August 12, 2026 (7:00 pm ET start time) is Mariners 3 Yankees 1.

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Seattle Mariners: 35-57 (-27.1 units) on the moneyline against AL East opponents. 237-219 (-22.6 units) on the moneyline in all games. 101-124 (-33.5 units) on the moneyline in road games. 19-13 UNDER when the total is 8 to 8.5.

New York Yankees: 153-95 (+11.9 units) on the moneyline vs. an AL team with a slugging percentage .410 or worse on the season. 119-73 (+7.6 units) on the moneyline vs. AL teams scoring 4.4 or less runs/game on the season. 27-23 (+3.2 units) on the moneyline when the money line is +125 to -125. 37-22 UNDER when the money line is -100 to -150.

Seattle Mariners:  C. Sulser (RP) Fifteen Day IL - Oblique. L. Raley (RF) Ten Day IL - Elbow. J. Crawford (SS) Ten Day IL - Wrist. W. Wilson (3B) Sixty Day IL - Thumb. M. Brash (RP) Fifteen Day IL - Lat. C. Criswell (RP) Sixty Day IL - Shoulder. C. Vargas (RP) Sixty Day IL - Lat. L. Evans (SP) Sixty Day IL - Arm.

New York Yankees:  C. Bellinger (LF) Ten Day IL - Leg. A. Judge (RF) Sixty Day IL - Rib. C. Rodon (SP) Fifteen Day IL - Elbow. G. Stanton (DH) Ten Day IL - Leg. C. Schmidt (SP) Sixty Day IL - Elbow.

“We had him on the ropes early, and we weren’t able to convert it. At that point, he was able to settle in. He had a pretty good changeup today, kept us off-guard going back-and-forth with that. Not able to square anything up, not able to find barrels consistently. When we did find some barrels, it seemed like there was a guy standing there. It’s frustrating.” - Dan Wilson after his team’s loss against the Rays in their game on Sunday. 

“We’ve got to do more and put some runs on. But unlike some of the other games where we’ve been shut down, I do feel like we were getting some good swings off them. We had better at-bats as a club, but we’ve still got to find a way to push them across.” - Aaron Boone after his team’s loss against the Braves in their game on Sunday. 

Taylor Ward (R) RF

Cole Young (L) 2B

Randy Arozarena (R) LF

Dominic Canzone (L) DH

Julio Rodríguez (R) CF

Josh Naylor (L) 1B

Cal Raleigh (S) C

Weston Wilson (R) 3B

Colt Emerson (L) SS

Trent Grisham (L) CF

Ben Rice (L) DH

Heliot Ramos (R) LF

Luis García Jr. (L) 1B

Jazz Chisholm Jr. (L) 2B

Spencer Jones (L) RF

George Lombard Jr. (R) SS

Ryan McMahon (L) 3B

Austin Wells (L) C

Batting Average:  Randy Arozarena (.276)

Hits:  Cole Young (115)

Home Runs:  Dominic Canzone (18)

RBI:  Cole Young (52)

Stolen Bases:  Josh Naylor (23)

Wins:  George Kirby (8)

Saves:  Andrés Muñoz (20)

ERA:  Matt Brash (0.54)

Batting Average:  George Lombard (.294)

Hits:  Ben Rice (108)

Home Runs:  Ben Rice (32)

RBI:  Ben Rice (75)

Stolen Bases:  Jazz Chisholm (30)

Wins:  Cam Schlittler (10)

Saves:  David Bednar (26)

ERA:  Yerry De los Santos (1.00)

Managers:

Seattle Mariners: Dan Wilson (3rd season)

New York Yankees: Aaron Boone (9th season)