Seattle Mariners vs Minnesota Twins Prediction, Preview and Odds - 06/24/2025

Game Time: 7:40 pm ET, Tuesday, June 24, 2025

Venue:  Target Field, Minneapolis, MN

Where to Watch:  ROOT Sports NW, TWINS.tv

DraftKings:  Moneyline odds:  Mariners -105, Twins -115; Over/Under:  8.5 runs

Bet365:  Moneyline odds:  Mariners -105, Twins -115; Over/Under:  8.5 runs

BetMGM:  Moneyline odds:  Mariners -105, Twins -115; Over/Under:  8.5 runs

Seattle Mariners:  39-37 (2nd place, AL West)

Minnesota Twins:  37-40 (4th place, AL Central)

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Seattle Mariners:  6-4 last 10

Minnesota Twins:  1-9 last 10

The Mariners are entering this series off a win and won their 3-game series against the Chicago Cubs 2-1 in their last series. They enter this game with a 39-37 record overall and have a road record of 19-18. This is the 2nd game of a 4-game series with the Twins on Tuesday with the series opener still to be played on Monday. Their offense ranks 9th in the MLB with a .735 OPS. Bryan Woo is their starting pitcher on Monday while Luis Castillo is making his start in this game on Tuesday. He is 4-5 with a 3.38 ERA this season. His team lost 2 of their last 3 games this season with him making an appearance. In his last MLB regular season start, he allowed 3 ER, 2 HR, and 2 BB with 5 SO on 3 hits through 6 IP against the Boston Red Sox.

The Twins are entering this series off a loss and got swept in their 3-game series against the Milwaukee Brewers 3-0 in their last series. They enter this game with a 37-40 record overall and have a home record of 20-15. This is the 2nd game of a 4-game series with the Mariners on Tuesday with the 1st game of this series still to be played on Monday. Their offense ranks 16th in the MLB with a .711 OPS. Bailey Ober is their starting pitcher on Monday while Chris Paddack is making his start in this game on Tuesday. He is 3-6 with a 4.48 ERA this season. His team lost 5 of their last 6 games this season with him making an appearance. In his last MLB regular season start, he allowed 4 earned runs, 1 homer, and 0 walks with 3 strikeouts on 6 hits through 5 innings pitched against the Cincinnati Reds.

The current betting odds have the Mariners listed as a slight underdog in this game according to Draftkings Sportsbook. The Mariners have looked good in their games this season with their 39-37 record overall which has them right near the top of the AL West. They have been a good road team too with their 19-18 road record this season. Meanwhile, the Twins haven't looked great in their games this season with their 37-40 record overall which has them right near the bottom of the AL Central. They have looked better in their own ballpark though with their 20-15 home record this season. The Twins haven't been good lately though as they have been in a big slump and they are now 1-9 in their last 10 games. The Mariners have a lot more momentum coming into this series, off a series win over the Cubs on the weekend, and they can take advantage of this pitching matchup with that much better offense. The Twins are going with Paddack in this one and he hasn't looked great this season. He is 3-6 with a 4.48 ERA and has been giving up quite a few runs in his starts lately. He just gave up 4 earned runs in his last start which has been a common theme lately, and the team has been terrible with him too, losing 5 of the last 6 games he started in. The Mariners are going with Castillo in this one and he hasn't looked his best this year, but he is still the more reliable starter in this matchup. He is 4-5 with a 3.38 ERA and hasn't been giving up a ton of runs in his starts. His team has lost 2 of the last 3 games he started in and he did give up 3 earned runs in his last start, but he will be looking to bounce back here and will pitch better against this slumping Twins team. The Mariners also have the hot offense right now to bail themselves out too. The best way to place a bet here is on the Mariners to win this game. 

Mariners Twins Prediction:  Our MLB Pick for Tuesday, June 24, 2025 (7:40 pm ET start time) is Mariners 7 Twins 3.

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Seattle Mariners: 91-85 (+5.3 units) on the moneyline when the money line is +125 to -125. 135-103 (+8 units) on the moneyline vs. an AL team with an on base percentage .330 or worse. 85-57 (+5.1 units) on the moneyline vs. AL teams scoring 4.4 or less runs/game on the season. 45-29 OVER as a road underdog of +100 to +150.

Minnesota Twins: 208-198 (-36.1 units) on the moneyline in all games. 112-89 (-15.4 units) on the moneyline in home games. 158-118 (-15.4 units) on the moneyline as a favorite of -110 or higher. 51-33 OVER against AL West opponents.

Seattle Mariners:  T. Thornton (RP) Day To Day - Heat Illness. B. Miller (SP) Fifteen Day IL - Elbow. C. Snider (RP) Fifteen Day IL - Forearm. G. Santos (RP) Sixty Day IL - Knee. V. Robles (RF) Sixty Day IL - Shoulder. R. Bliss (2B) Sixty Day IL - Biceps.

Minnesota Twins:  W. Castro (2B) Day To Day - Wrist. R. Lewis (3B) Ten Day IL - Hamstring. P. Lopez (SP) Sixty Day IL - Shoulder. Z. Matthews (SP) Fifteen Day IL - Shoulder. L. Keaschall (2B) Sixty Day IL - Forearm.

“A really nice job by everybody on offense, but Donnie in particular, and Dom, taking advantage of getting an opportunity and making the most of it.” - Dan Wilson after his team’s win against the Cubs in their game on Sunday.

“[It gives] us a chance to go out there, start a good reliever at the beginning of the game and then kind of run from there. It also leaves the other team guessing a little bit. A lot of reasons for it but I think it’s something that can help us and probably something that we’re going to see more of.” - Rocco Baldelli after his team’s loss against the Brewers in their game on Sunday.

J.P. Crawford (L) SS

Julio Rodríguez (R) CF

Cal Raleigh (S) DH

Jorge Polanco (S) 2B

Randy Arozarena (R) LF

Mitch Garver (R) C

Donovan Solano (R) 1B

Dominic Canzone (L) RF

Miles Mastrobuoni (L) 3B

Byron Buxton (R) CF

Matt Wallner (L) RF

Trevor Larnach (L) DH

Ty France (R) 1B

Brooks Lee (S) 3B

Carlos Correa (R) SS

Kody Clemens (L) 2B

Ryan Jeffers (R) C

DaShawn Keirsey Jr. (L) LF

Batting Average:  J.P. Crawford (.291)

Hits:  Julio Rodríguez (78)

Home Runs:  Cal Raleigh (31)

RBI:  Cal Raleigh (66)

Stolen Bases:  Randy Arozarena (14)

Wins:  Bryan Woo (6)

Saves:  Andrés Muñoz (18)

ERA:  Matt Brash (0.00)

Batting Average:  Luke Keaschall (.368)

Hits:  Ty France (73)

Home Runs:  Byron Buxton (17)

RBI:  Byron Buxton (47)

Stolen Bases:  Byron Buxton (13)

Wins:  Joe Ryan (7)

Saves:  Jhoan Duran (10)

ERA:  Danny Coulombe (0.87)

Managers:

Seattle Mariners: Dan Wilson (2nd season)

Minnesota Twins: Rocco Baldelli (7th season)