Seattle Mariners vs Baltimore Orioles Prediction, Preview and Odds - 06/10/2026

Game Time: 6:35 pm ET, Wednesday, June 10, 2026

Venue:  Oriole Park at Camden Yards, Baltimore, MD

Where to Watch:  MLB TV

DraftKings:  Moneyline odds:  Mariners -126, Orioles +104; Over/Under:  9 runs

Bet365:  Moneyline odds:  Mariners -125, Orioles +105; Over/Under:  9 runs

BetMGM:  Moneyline odds:  Mariners -125, Orioles +105; Over/Under:  9 runs

Seattle Mariners:  35-32 (1st place, AL West)

Baltimore Orioles:  31-36 (4th place, AL West)

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Seattle Mariners:  7-3 last 10

Baltimore Orioles:  5-5 last 10

The Mariners are entering this series off a loss and lost their 3-game series against the Detroit Tigers 2-1 in their last series. They enter this game with a 35-32 record overall and have a road record of 16-16. This is the 3rd game of a 4-game series with the Orioles on Wednesday with the 2nd game still to be played on Tuesday. The Mariners won the series opener on Monday. Their offense ranks 12th in the MLB with a .718 OPS. Logan Gilbert is their starting pitcher on Tuesday while George Kirby is making his start in this game on Wednesday. He is 5-5 with a 4.04 ERA this season. His team lost 3 of their last 4 games this season with him making an appearance. In his last MLB regular season appearance, he allowed 4 ER, 0 HR, and 1 BB with 5 SO on 9 hits through 4 IP against the New York Mets.

The Orioles are entering this series off a loss and lost their 3-game series against the Toronto Blue Jays 2-1 in their last series. They enter this game with a 31-36 record overall and have a home record of 19-16. This is the 3rd game of a 4-game series with the Mariners on Wednesday with the 2nd game of this series still to be played on Tuesday. The Orioles lost the 1st game of this series on Monday. Their offense ranks 11th in the MLB with a .719 OPS. Trevor Rogers is their starting pitcher on Tuesday while Brandon Young is making his start in this game on Wednesday. He is 4-1 with a 3.47 ERA this season. His team won their last 6 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 3 earned runs, 1 homer, and 0 walks with 4 strikeouts on 7 hits through 6.1 innings pitched against the Toronto Blue Jays.

The current betting odds have the Orioles listed as a slight underdog in this game according to Draftkings Sportsbook. The Mariners have looked good in their games this season with their 35-32 record overall which has them right at the top of the AL West. They haven't been a great road team though with their 16-16 road record this year. Meanwhile, the Orioles haven't looked great in their games this season with their 31-36 record overall which has them right near the bottom of the AL East. They have looked a lot better in their own ballpark though with their 19-16 home record this season. The Mariners are 7-3 in their last 10 games and they have been rolling after a bad start to the season, but lately they have been cooling off a bit from that hot streak. The Orioles are only 5-5 in their last 10 games and haven't looked great lately, but their offense has looked a lot better over the last week and this is definitely a pitching matchup that they can take advantage of. Kirby is on the mound for the Mariners in this one and he hasn't looked great this season. He is 5-5 with a 4.04 ERA and his team hasn't had a lot of success with him lately. They have lost 3 of their last 4 games with him starting and he is coming off a start in which he gave up 4 earned runs, something that has been becoming a common theme lately. The Orioles are going with Young in this one and he hasn't looked bad this year. He is 4-1 with a 3.47 ERA and his team has been having a ton of success with him lately. He did give up 3 earned runs in his last start, but he hasn't looked that bad lately and the team has won 6 games in a row now with him starting. The Orioles should get a good performance out of him at home and they definitely have the offense to put up some runs in this one. The best way to place a bet here is on the Orioles to win this game. 

Mariners Orioles Prediction:  Our MLB Pick for Wednesday, June 10, 2026 (6:35 pm ET start time) is Orioles 6 Mariners 4.

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Seattle Mariners: 28-45 (-21 units) on the moneyline against AL East opponents. 216-187 (-7.1 units) on the moneyline in all games. 94-106 (-22 units) on the moneyline in road games. 19-9 UNDER when the money line is +125 to -125.

Baltimore Orioles: 22-21 (+4.5 units) on the moneyline as a home underdog of +100 or higher. 44-38 (+12.5 units) on the moneyline vs. good power teams - averaging 1.25 or more HR's/game. 69-68 (+1.8 units) on the moneyline vs. an AL starting pitcher whose WHIP is 1.300 or better. 28-14 UNDER as a home underdog of +100 or higher.

Seattle Mariners:  C. Emerson (3B) Day To Day - Back. J. Crawford (SS) Ten Day - Hand. B. Donovan (3B) Ten Day IL - Groin. C. Raleigh (C) Ten Day IL - Side. W. Wilson (3B) Ten Day IL - Thumb. M. Mastrobuoni (3B) Sixty Day IL - Calf. C. Vargas (RP) Sixty Day IL - Lat. L. Evans (SP) Sixty Day IL - Arm.

Baltimore Orioles:  C. Bassitt (SP) Fifteen Day - Back. D. Beavers (RF) Ten Day IL - Oblique. C. Povich (SP) Fifteen Day IL - Elbow. R. Helsley (RP) Fifteen Day IL - Elbow. D. Kremer (SP) Sixty Day IL - Quad. R. Mountcastle (1B) Sixty Day IL - Foot. Y. Hiraldo (RP) Sixty Day IL - Shoulder. Z. Eflin (SP) Sixty Day IL - Elbow. J. Westburg (3B) Sixty Day IL - UCL. F. Bautista (RP) Sixty Day IL - Shoulder. C. Selby (SP) Sixty Day IL - Shoulder.

“It's one of those things -- the umpire makes the call, and it's worth checking. You've got to try to check it. He's seeing it live, and it was pretty bang-bang. But Jake was all over it. And that's a huge turnaround right there. It's a huge lift.” - Dan Wilson on his key challenge in his team’s win against the Orioles in their game on Monday. 

"Going into it we knew we had to grind and force them to work (on the mound) and we did that. We just couldn’t come through with the big blow." - Craig Albernaz after his team’s loss against the Mariners in their game on Monday. 

Cole Young (L) SS

Julio Rodríguez (R) CF

Josh Naylor (L) 1B

Randy Arozarena (R) LF

Luke Raley (L) RF

Dominic Canzone (L) DH

Patrick Wisdom (R) 3B

Jhonny Pereda (R) C

Ryan Bliss (R) 2B

Taylor Ward (R) LF

Gunnar Henderson (L) DH

Pete Alonso (R) 1B

Colton Cowser (L) CF

Leody Taveras (S) RF

Jackson Holliday (L) 2B

Coby Mayo (R) 3B

Blaze Alexander (R) SS

Sam Huff (R) C

Batting Average:  Randy Arozarena (.293)

Hits:  Randy Arozarena (72)

Home Runs:  Luke Raley (13)

RBI:  Julio Rodríguez (32)

Stolen Bases:  Randy Arozarena (18)

Wins:  George Kirby (5)

Saves:  Andrés Muñoz (10)

ERA:  Nick Davila (0.00)

Batting Average:  Ryan Mountcastle (.286)

Hits:  Taylor Ward (63)

Home Runs:  Pete Alonso (13)

RBI:  Pete Alonso (41)

Stolen Bases:  Blaze Alexander (7)

Wins:  Chris Bassitt (4)

Saves:  Ryan Helsley (7)

ERA:  Jose Espada (0.00)

Managers:

Seattle Mariners: Dan Wilson (3rd season)

Baltimore Orioles: Craig Albernaz (1st season)