San Francisco Giants vs Philadelphia Phillies Prediction, Preview and Odds - 04/17/2025

Game Time: 4:05 pm ET, Thursday, April 17, 2025

Venue:  Citizens Bank Park, Philadelphia, PA 

Where to Watch:  NBCSP+

DraftKings:  Moneyline odds:  Giants +140, Phillies -166; Over/Under:  8 runs

Bet365:  Moneyline odds:  Giants +140, Phillies -165; Over/Under:  8 runs

BetMGM:  Moneyline odds:  Giants +140, Phillies -165; Over/Under:  8 runs

San Francisco Giants:  12-5 (2nd place, NL West)

Philadelphia Phillies:  10-7 (2nd place, NL East)

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San Francisco Giants:  6-4 last 10

Philadelphia Phillies:  4-6 last 10

The Giants are entering this series off a win and won their 3-game series against the New York Yankees 2-1 in their last series. They enter this game with a 12-5 record overall and have a road record of 8-3. This is the series finale of a 4-game series with the Phillies on Thursday with the 3rd game still to be played on Wednesday. The Giants won the series opener on Monday and the Phillies won the 2nd game on Tuesday. Their offense ranks 10th in the MLB with a .717 OPS. Robbie Ray is their starting pitcher on Wednesday while Jordan Hicks is making his start in this game on Thursday. He is 1-1 with a 5.87 ERA this season. His team won 2 of their last 3 games this season with him making an appearance. In his last MLB regular season start, he allowed 7 ER, 0 HR, and 3 BB with 3 Ks on 8 hits through 4 IP against the New York Yankees.

The Phillies are entering this series off a loss and lost their 3-game series against the St Louis Cardinals 2-1 in their last series. They enter this game with a 10-7 record overall and have a home record of 6-2. This is the 4th game of a 4-game series with the Giants on Thursday with the 3rd game still to be played on Wednesday. The Giants won the 1st game of this series on Monday and the Phillies won the 2nd game on Tuesday. Their offense ranks 10th in the MLB with a .717 OPS. Aaron Nola is their starting pitcher on Wednesday while Cristopher Sánchez is making his start in this game on Thursday. He is 1-0 with a 3.12 ERA this season. His team won their last 3 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 1 earned run, 0 homers, and 2 BB with 3 strikeouts on 8 hits through 6.1 innings played against the St Louis Cardinals.

The current betting odds have the Phillies listed as a favorite in this game according to Draftkings Sportsbook. The Phillies have looked good in their games this season with their 10-7 record overall which has them right near the top of their division with a good start to the season. They have also looked good in their own ballpark this year with their 6-2 home record. Meanwhile, the Giants have looked really good in their games this season with their 12-5 record overall which has them right near the top of their division with one of the best records in the entire MLB. They have also been a great road team so far with their 8-3 road record. Both of these teams have been similar on offense this season and they have split the first 2 games of this series too, but the Phillies have the better pitching matchup in this one and that should get them the win at home. The Giants are going with Hicks here and he hasn't been great this season. He is coming off a bad start which he gave up 7 earned runs and it isn't going to be any easier for him here against this Phillies offense. This is a tough game for him to bounce back in with the Phillies offense starting to get hot again. The Phillies are also going to have Sanchez on the mound here and he has been great this season. His team has won all 3 of his starts this season and he hasn't been giving up many runs in those games, only giving up 1 earned run in his last start too. The Phillies have been struggling lately, but they have been great at home so far and this is a game that they can take advantage of the Giants in with Hicks' bad start to the season. The best way to place a bet here is on the Phillies to win this game. 

Giants Phillies Prediction:  Our MLB Pick for Thursday, April 17, 2025 (4:05 pm ET start time) is Phillies 8 Giants 4.

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San Francisco Giants: 30-36 (-11.3 units) on the moneyline against NL East opponents. 171-169 (-12.9 units) on the moneyline in all games. 75-72 (-11 units) on the moneyline vs. a team with a poor bullpen whose ERA is 4.20 or worse. 34-27 UNDER against NL East opponents.

Philadelphia Phillies: 49-31 (+9.5 units) on the moneyline against NL West opponents. 116-63 (+21 units) on the moneyline in home games. 104-50 (+20.3 units) on the moneyline as a home favorite of -110 or higher. 26-16 UNDER vs. a team with a good bullpen whose ERA is 3.45 or better.

San Francisco Giants:  T. Murphy (C) Sixty Day IL - Back. J. Encarnacion (RF) Ten Day IL - Finger.

Philadelphia Phillies:  W. Wilson (LF) Ten Day IL - Oblique. R. Suarez (SP) Fifteen Day IL - Back.

“Every game is its own personality. I mean, look, he’s had a lot of success, and that may have played into it some, but I wanted to give him a chance to get that last out.” - Bob Melvin after his team’s loss against the Phillies in their game on Tuesday.

“That’s the game right there, right? “You think, ‘Oh, there was my chance.’ You can either let that go one way and ruin the rest of the day, or just keep playing the game. And you know, the game gives you another opportunity. So, I think just play the game, take what it gives you.” - Alec Bohm on breaking out of his slump in their win against the Giants on Tuesday.

Heliot Ramos (R) LF

Willy Adames (R) SS

Jung Hoo Lee (L) CF

Matt Chapman (R) 3B

Wilmer Flores (R) DH

Casey Schmitt (R) 1B

Luis Matos (R) RF

Patrick Bailey (S) C

Tyler Fitzgerald (R) 2B

Bryson Stott (L) 2B

Trea Turner (R) SS

Bryce Harper (L) 1B

Kyle Schwarber (L) DH

Nick Castellanos (R) RF

J.T. Realmuto (R) C

Max Kepler (L) LF

Alec Bohm (R) 3B

Brandon Marsh (L) CF

Batting Average:  Jung Hoo Lee (.333)

Hits:  Jung Hoo Lee (21)

Home Runs:  Wilmer Flores (6)

RBI:  Wilmer Flores (21)

Stolen Bases:  Tyler Fitzgerald (4)

Wins:  Robbie Ray (3)

Saves:  Ryan Walker (4)

ERA:  Randy Rodríguez (0.00)

Batting Average:  Edmundo Sosa (.444)

Hits:  Nick Castellanos (19)

Home Runs:  Kyle Schwarber (6)

RBI:  Kyle Schwarber (12)

Stolen Bases:  Trea Turner (4)

Wins:  Jesús Luzardo (2)

Saves:  José Alvarado (3)

ERA:  Matt Strahm (1.08)

Managers:

San Francisco Giants: Bob Melvin (2nd season)

Philadelphia Phillies: Rob Thomson (4th season)