San Francisco 49ers vs Seattle Seahawks Prediction, Preview and Odds - 11/23/2023

by Rod Pearson

Tuesday, Nov 21, 2023
Game Time: 8:20 pm ET, Thursday, November 23, 2023
Venue:  Lumen Field, Seattle, WA
Where to Watch:  NBC


Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  49ers -6.5, Seahawks +6.5; Over/Under:  43.5 points
Bet365:  Point Spread:  49ers -6.5, Seahawks +6.5; Over/Under:  43.5 points
BetMGM:  Point Spread:  49ers -6.5, Seahawks +6.5; Over/Under:  43 points

Season Record

San Francisco 49ers:  7-3 (1st place, NFC West)
Seattle Seahawks:  6-4 (2nd place, NFC West)

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Recent Form
San Francisco 49ers:  won their last game at home against the Tampa Bay Buccaneers 27-14.
Seattle Seahawks:  lost their last game on the road against the Los Angeles Rams 17-16.


San Francisco 49ers vs Seattle Seahawks Preview and Analysis


The 49ers are entering this game with a 7-3 record overall and they have a 2-0 record in their divisional games too. They are 4-1 in their home games, 3-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Tampa Bay Buccaneers 27-14. Brock Purdy was the starting QB and he completed 21/25 passes for 333 passing yards, 3 touchdowns, and 0 interceptions. Christian McCaffrey led the team in rushing yards with 78. Brandon Aiyuk led the receivers with 156 receiving yards on 5 receptions and 1 TD. Fred Warner led the defense in that game with 10 solo tackles and 2 assisted tackles while Arik Armstead, Chase Young, and Nick Bosa each led the defense in sacks with 1. Ji'Ayir Brown came away with the only interception for them in that game.
 
 
 
The Seahawks are entering this game with a 6-4 record overall and they have a 1-2 record in their divisional games too. They are 4-1 in their home games, 2-3 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the LA Rams 17-16. Geno Smith was the starting QB and he completed 22/34 passes for 233 passing yards, 1 touchdown, and 0 interceptions. Zach Charbonnet led the team in rushing yards with 47. DK Metcalf led the receivers with 94 receiving yards on 5 receptions and 1 TD. Quandre Diggs led the defense in that game with 8 solo tackles and 5 assisted tackles while Devon Witherspoon led the defense in sacks with 1. Tariq Woolen came away with the only interception for them in that game.


49ers vs Seahawks Prediction

The current betting odds have the 49ers listed as a 6.5 point favorite in this game according to Draftkings Sportsbook. The 49ers have looked really good this season with their 7-3 record overall. They were one of the best teams in the league to start the season and went through a bit of a rough patch, but they have come out of their bye week very hot with 2 wins in a row and both wins coming by double digits. The Seahawks have also looked good this season with their 6-4 record overall but they haven't looked as good in their games lately. The Seahawks have been finding ways to win games all season but lately their wins have been much closer in score and their games have been going down to the last minute, usually needing a game winning drive. They haven't played well in the division this season either as they are only 1-2 against NFC West teams while the 49ers are 2-0 in divisional games and will be looking to take control of the NFC West with another win here. The best way to place a bet here is on the 49ers to cover the spread in this game. 

49ers Seahawks Prediction:  Our NFL Pick for Thursday, November 23, 2023 (8:20 pm ET start time) is 49ers 31 Seahawks 17.
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NFL Betting Trends


San Francisco 49ers: 30-19 ATS in all games. 24-16 ATS as a favorite. 11-4 ATS versus division opponents. 11-4 UNDER as a road favorite of 7 points or less. 16-8 UNDER in road games. 12-5 UNDER in a road game where the total is between 42.5 and 49 points. 

Seattle Seahawks: 4-9 ATS off a division game. 1-8 ATS after gaining 75 or less rushing yards last game. 6-1 UNDER as a home underdog. 11-5 UNDER versus division opponents. 9-5 UNDER in a home game where the total is between 42.5 and 45 points.

Key Injuries


San Francisco 49ers:  T. Hufanga (S) out for season - Knee. A. Banks (OL) Ques Thurs - Toe. S. Womack III (CB) Ques Thurs - Knee. R. Beal Jr. (DL) Ques Thurs - Hamstring. N. Zakelj (OL) I-R - Bicep. D. Jackson (DL) Out indefinitely - Knee. D. Gray (WR) Out indefinitely - Shoulder. C. Latu (TE) I-R - Knee.

Seattle Seahawks:  G. Smith (QB) Ques Thurs - Elbow. K. Walker III (RB) Ques Thurs - Oblique. D. Young (WR) Ques Thurs - Abdominal. A. Lucas (OT) Ques Thurs - Knee. K. McIntosh (RB) Ques Thurs - Knee. D. Thomas (LB) Out indefinitely - Knee. U. Nwosu (LB) I-R - Pectoral. C. Bryant (CB) Out indefinitely - Toe. M. Morris (DE) Out indefinitely - Shoulder. B. Mone (DT) Out indefinitely - Knee.

Notable Quotes


“Brock’s been great because he's been consistent through it all. I never felt any difference with Brock during those three losses. I think he's pretty realistic so he doesn’t get into stuff that’s not that accurate.” - Kyle Shanahan after his team’s win against the Bucs in their last game. 


“This was the most disappointing loss for us because of the way we did it. We made it really hard on ourselves so many times in this game with the calls that were made. And I’m not disputing any of them. I’m just saying the penalties that happened were just out of line for us. We have not been good in that area during the season in general, and today it really blew up on us.” - Pete Carroll after his team’s loss against the LA Rams in their last game. 


Starting Lineups


San Francisco 49ers
WR Aiyuk, Brandon 
WR Samuel, Deebo 
WR Jennings, Jauan 
TE Kittle, George 
QB Purdy, Brock 
RB McCaffrey, Christian 
FB Juszczyk, Kyle

Seattle Seahawks
WR Metcalf, DK 
WR Lockett, Tyler 
WR Smith-Njigba, Jaxon 
TE Fant, Noah 
QB Smith, Geno 
RB Walker III, Kenneth 

Statistical Leaders


San Francisco 49ers
Passing: B. Purdy (2662)
Rushing: C. McCaffrey (825)
Receiving: B. Aiyuk (831)
Touchdowns: C. McCaffrey (14)

Seattle Seahawks
Passing: G. Smith (2404)
Rushing: K. Walker III (613)
Receiving: D. Metcalf (646)
Touchdowns: K. Walker III (7)

Coaches:
San Francisco 49ers: Kyle Shanahan (7th season)
Seattle Seahawks: Pete Carroll (14th season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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