San Francisco 49ers vs Minnesota Vikings Prediction, Preview and Odds - 10/23/2023

by Rod Pearson

Wednesday, Oct 18, 2023
Game Time: 8:15 pm ET, Monday, October 23, 2023
Venue:  U.S. Bank Stadium, Minneapolis, MN
Where to Watch:  ESPN, ABC


Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  49ers -6.5, Vikings +6.5; Over/Under:  44 points
Bet365:  Point Spread:  49ers -7, Vikings +7; Over/Under:  44 points
BetMGM:  Point Spread:  49ers -7, Vikings +7; Over/Under:  44 points

Season Record

San Francisco 49ers:  5-1 (1st place, NFC West)
Minnesota Vikings:  2-4 (3rd place, NFC North)

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Recent Form
San Francisco 49ers:  lost their last game on the road against the Cleveland Browns 19-17.
Minnesota Vikings:  won their last game on the road against the Chicago Bears 19-13.


San Francisco 49ers vs Minnesota Vikings Preview and Analysis


The 49ers are entering this game with a 5-1 record overall and they have a 2-0 record in their divisional games too. They are 3-0 in their home games, 2-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the Cleveland Browns 19-17. Brock Purdy was the starting QB and he completed 12/27 passes for 125 passing yards, 1 touchdown, and 1 interception. Christian McCaffrey led the team in rushing yards with 43. Brandon Aiyuk led the receivers with 76 receiving yards on 4 receptions. Talanoa Hufanga led the defense in that game with 5 solo tackles and 2 assisted tackles while Randy Gregory and Nick Bosa each led the defense in sacks with 1. Deommodore Lenoir and Fred Warner each came away with 1 interception for them in that game.
 
 
 
The Vikings are entering this game with a 2-4 record overall and they have a 1-0 record in their divisional games too. They are 0-3 in their home games, 2-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Chicago Bears 19-13. Kirk Cousins was the starting QB and he completed 21/31 passes for 181 passing yards, 1 touchdown, and 0 interceptions. Alexander Mattison led the team in rushing yards with 44. T.J. Hockenson led the receivers with 50 receiving yards on 6 receptions. Camryn Bynum led the defense in that game with 9 solo tackles and 0 assisted tackles while Danielle Hunter led the defense in sacks with 2. Jordan Hicks and Byron Murphy Jr. each came away with 1 interception for them in that game.


49ers vs Vikings Prediction

The current betting odds have the 49ers listed as a 6.5 point favorite in this game according to Draftkings Sportsbook. The 49ers have been having a great season with their 5-1 record overall but they are also coming off their 1st loss of the season in Cleveland. They looked terrible in that game but they have a much better matchup here against one of the worst defenses in the NFL and they will be looking to bounce back. The Vikings are only 2-4 this season as they have struggled in all of their games and they were even very fortunate to beat the Bears last week after Fields went down in the game. The 49ers have the better offense over the Vikings and as good as the Vikings have been on offense this year, they are going to struggle against one of the best defenses in the league here while the 49ers tear apart that terrible Vikings defense that has been giving up points all season. The best way to place a bet here is on the 49ers to cover the spread in this game. 

49ers Vikings Prediction:  Our NFL Pick for Monday, October 23, 2023 (8:15 pm ET start time) is 49ers 31 Vikings 17.
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NFL Betting Trends


San Francisco 49ers: 29-16 ATS in all games. 23-13 ATS as a favorite. 24-9 ATS against conference opponents. 14-8 OVER as a favorite of 3.5 to 9.5 points. 8-3 OVER off a non-conference game. 9-4 OVER after 2 consecutive games with a turnover margin of +1 or better.

Minnesota Vikings: 2-8 ATS after a win by 6 or less points. 7-13 ATS after 1 or more consecutive wins. 7-0 OVER as an underdog of 3.5 to 9.5 points. 11-4 OVER in a home game where the total is between 42.5 and 49 points. 8-3 OVER off a division game.

Key Injuries


San Francisco 49ers:  D. Greenlaw (LB) Ques Mon - Hamstring. T. Williams (OT) Ques Mon - Ankle. C. McCaffrey (RB) Ques Mon - Oblique. D. Samuel (WR) Ques Mon - Shoulder. S. Womack III (CB) Out indefinitely - Knee. R. Beal Jr. (DL) Out indefinitely - Hamstring. D. Gray (WR) Out indefinitely - Shoulder. D. Luter Jr. (CB) Out indefinitely - Knee. C. Latu (TE) I-R - Knee.

Minnesota Vikings:  K. Nwangwu (RB) Ques Mon - Back. L. Cine (S) Ques Mon - Hamstring. M. Davenport (LB) Late Nov - Ankle. J. Jefferson (WR) Late Nov - Hamstring. N. Mullens (QB) Out indefinitely - Back. J. Nailor (WR) Out indefinitely - Hamstring. O. Udoh (G) I-R - Quadricep. J. Lynch (DL) I-R - Knee.

Notable Quotes


“I didn’t play at the standard that I needed to. We feel like we failed our own expectations. I just have to be better and make the throws. Man, it’s the NFL. When you get opportunities, you’ve got to take care of them. There are plays that we didn’t make.” - Brock Purdy after their loss against the Browns in their last game. 


“It just felt like he was not going to be denied a chance to be the guy or to go out there and respond. How he was on the sideline, how he was all week in prep — I'm really, really happy with Jordan. Proud of him, as one of our core leaders showing up the way he did today.” - Kevin O’Connell after his team’s win against the Bears in their last game. 


Starting Lineups


San Francisco 49ers
WR Aiyuk, Brandon 
WR Samuel, Deebo 
WR Jennings, Jauan 
TE Kittle, George 
QB Purdy, Brock 
RB McCaffrey, Christian 
FB JUSZCZYK, KYLE

Minnesota Vikings
WR Osborn, K.J.
WR Addison, Jordan
WR Powell, Brandon  
TE Hockenson, T.J. 
QB COUSINS, KIRK 
RB Mattison, Alexander 
FB HAM, C.J.

Statistical Leaders


San Francisco 49ers
Passing: B. Purdy (1396)
Rushing: C. McCaffrey (553)
Receiving: B. Aiyuk (454)
Touchdowns: C. McCaffrey (9)

Minnesota Vikings
Passing: K. Cousins (1679)
Rushing: A. Mattison (320)
Receiving: J. Jefferson (571)
Touchdowns: J. Addison (4)

Coaches:
San Francisco 49ers: Kyle Shanahan (7th season)
Minnesota Vikings: Kevin O'Connell (2nd season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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