San Francisco 49ers vs Jacksonville Jaguars Prediction, Preview and Odds - 11/12/2023

by Rod Pearson

Monday, Nov 06, 2023
Game Time: 1:00 pm ET, Sunday, November 12, 2023
Venue:  TIAA Bank Field, Jacksonville, FL 
Where to Watch:  FOX


Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  49ers -3, Jaguars +3; Over/Under:  44.5 points
Bet365:  Point Spread:  49ers -3, Jaguars +3; Over/Under:  45 points
BetMGM:  Point Spread:  49ers -3, Jaguars +3; Over/Under:  45 points

Season Record

San Francisco 49ers:  5-3 (1st place, NFC West)
Jacksonville Jaguars:  6-2 (1st place, AFC South)

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Recent Form
San Francisco 49ers:  lost their last game at home against the Cincinnati Bengals 31-17.
Jacksonville Jaguars:  won their last game on the road against the Pittsburgh Steelers 20-10.


San Francisco 49ers vs Jacksonville Jaguars Preview and Analysis


The 49ers are entering this game with a 5-3 record overall and they have a 2-0 record in their divisional games too. They are 3-1 in their home games, 2-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the Cincinnati Bengals 31-17. Brock Purdy was the starting QB and he completed 22/31 passes for 365 passing yards, 1 touchdown, and 2 interceptions. Brock Purdy led the team in rushing yards with 57. George Kittle led the receivers with 149 receiving yards on 9 receptions. Talanoa Hufanga led the defense in that game with 8 solo tackles and 2 assisted tackles while Arik Armstead led the defense in sacks with 2. No one on the defense came away with an interception for them in that game.
 
 
 
The Jaguars are entering this game with a 6-2 record overall and they have a 2-1 record in their divisional games too. They are 1-2 in their home games, 3-0 in their road games, and they are also 2-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Pittsburgh Steelers 20-10. Trevor Lawrence was the starting QB and he completed 24/32 passes for 292 passing yards, 1 touchdown, and 1 interception. Travis Etienne Jr. led the team in rushing yards with 79. Evan Engram led the receivers with 88 receiving yards on 10 receptions. Foyesade Oluokun led the defense in that game with 9 solo tackles and 2 assisted tackles while Josh Allen led the defense in sacks with 2. Andrew Wingard and Antonio Johnson each came away with 1 interception for them in that game.


49ers vs Jaguars Prediction

The current betting odds have the Jaguars listed as a 3 point underdog in this game according to Draftkings Sportsbook. The Jaguars are 6-2 this season and after going through a rougher start to the year, they have looked really good in their games lately. They continue to win games as they have now won 5 games in a row and they are coming off their bye week for this game too. The 49ers are also coming off their bye week but they went into the bye stumbling with 3 losses in a row after starting the season 5-0 and the magic is starting to wear off with Brock Purdy now as he hasn't looked good in their last few games. They are also dealing with injuries as Deebo Samuel is still out and they are going to have a much tougher time on the road against a red hot Jacksonville who has been rolling over teams. The 49ers have not only had offensive troubles lately but their defense hasn't looked that good either and even if they pull off a win in this road game, it won't be by more than a field goal. The best way to place a bet here is on the Jaguars to cover the spread in this game. 

49ers Jaguars Prediction:  Our NFL Pick for Sunday, November 12, 2023 (1:00 pm ET start time) is Jaguars 23 49ers 20.
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NFL Betting Trends


San Francisco 49ers: 29-18 ATS in all games. 23-15 ATS as a favorite. 10-1 ATS off a non-conference game. 10-4 UNDER in games where the line is +3 to -3. 15-8 UNDER in road games. 11-5 UNDER in a road game where the total is between 42.5 and 49 points.

Jacksonville Jaguars: 7-21 ATS against NFC West division opponents. 3-8 ATS after 2 consecutive games with a turnover margin of -1 or worse. 9-2 UNDER after 2 consecutive games with a turnover margin of -1 or worse. 15-8 UNDER off 1 or more consecutive unders. 

Key Injuries


San Francisco 49ers:  T. Williams (T) Ques Week 10 - Ankle. D. Samuel (WR) Mid Nov - Shoulder. S. Womack III (CB) Out indefinitely - Knee. R. Beal Jr. (DL) Out indefinitely - Hamstring. D. Gray (WR) Out indefinitely - Shoulder. D. Luter Jr. (CB) Out indefinitely - Knee. C. Latu (TE) I-R - Knee.

Jacksonville Jaguars:  G. Junior (CB) Ques Week 10 - Hamstring. Z. Jones (WR) Ques Week 10 - Knee. T. Campbell (CB) Ques Week 10 - Hamstring. A. Cisco (S) Ques Week 10 - Hamstring. C. Braswell (CB) Out indefinitely - Hamstring. P. Washington (WR) Out indefinitely - Knee. L. Taylor (TE) I-R - Undisclosed. C. Hodges (OT) Out indefinitely - Knee. V. Miller (LB) I-R - Achilles.

Notable Quotes


“This isn't on any one coach or any one side of the ball. We haven't scored over 20 points here in three weeks too. I think our defense needs to be better, our offense needs to do better, our team needs to do better.” - Kyle Shanahan after his team’s loss against the Bengals in their last game. 


“It's part of what makes this game great. You want that fuel. You want to hate your opponent when they come in and make it as hard as possible. I totally understand that.” - Trevor Lawrence after their win against the Steelers in their last game. 


Starting Lineups


San Francisco 49ers
WR Aiyuk, Brandon 
WR Samuel, Deebo 
WR Jennings, Jauan 
TE Kittle, George 
QB Purdy, Brock 
RB McCaffrey, Christian 
FB JUSZCZYK, KYLE

Jacksonville Jaguars
WR Ridley, Calvin
WR Jones, Zay
WR Kirk, Christian 
TE Engram, Evan 
QB Lawrence, Trevor 
RB Etienne Jr., Travis

Statistical Leaders


San Francisco 49ers
Passing: B. Purdy (2033)
Rushing: C. McCaffrey (652)
Receiving: B. Aiyuk (620)
Touchdowns: C. McCaffrey (13)

Jacksonville Jaguars
Passing: T. Lawrence (1935)
Rushing: T. Etienne Jr. (583)
Receiving: C. Kirk (520)
Touchdowns: T. Etienne Jr. (8)

Coaches:
San Francisco 49ers: Kyle Shanahan (7th season)
Jacksonville Jaguars: Doug Pederson (2nd season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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