San Francisco 49ers vs Cincinnati Bengals Prediction, Preview and Odds - 12/12/2021

by Amedeus Mastrangelo

Monday, Dec 06, 2021
Game Time: 4:25 pm ET, Sunday, December 12, 2021
Venue:  Paul Brown Stadium, Cincinnati, OH 
Where to Watch:  CBS

 

Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  49ers +1, Bengals -1; Over/Under:  47.5 points
Bet365:  Point Spread:  49ers +1, Bengals -1; Over/Under:  47.5 points
BetMGM:  Point Spread:  49ers +1.5, Bengals -1.5; Over/Under:  47.5 points
 

Season Record

San Francisco 49ers:  6-6 (3rd place, NFC West)
Cincinnati Bengals:  7-5 (2nd place, AFC North)
 
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San Francisco 49ers vs Cincinnati Bengals Preview and Analysis

 
Recent Form
San Francisco 49ers:  lost on the road on Dec. 5 Against the Seattle Seahawks 30-23.
Cincinnati Bengals:  lost at home on Dec. 5 against the Los Angeles Chargers 41-22.
 
 
 

San Francisco 49ers Analysis

The SF 49ers are coming into this game with a 6-6 record overall and they are 4-2 in their road games this NFL season where they will be in this game. They have won 3 of their last 4 games but are coming into this one off of a loss in their last game which snapped a 3 game winning streak that they were on. Their 3 wins came against the Los Angeles Rams, the Jacksonville Jaguars, and the Minnesota Vikings while their loss came against the Seattle Seahawks in their last game. Jimmy Garoppolo completed 20/30 passes for 299 yards, 2 touchdowns and 2 interceptions. Eli Mitchell led the team in rushing with 66 yards and 1 touchdown on 22 carries. George Kittle had a very nice day as he led the receivers with 181 yards and 2 touchdowns on 9 receptions. Azeez Al-Shaair led the defense in that game with 11 solo tackles and 5 assisted ones. Nick Bosa, Arik Armstead, and Jordan Willis all led the defense in sacks in that game with 1 each while K'Waun Williams came up with the only interception for them in that one. They have scored 280 points in their 12 games this season averaging 23.3 PPG and they have allowed their opponents to score 248 points against them allowing 20.1 PPG. Their offense is averaging 334.7 YPG while their defense is allowing 292.2 YPG.
 
 

Cincinnati Bengals Analysis

The Bengals are coming into this game with a 7-5 record overall and they are 3-3 in their home games this season where they will be in this game. They have won 2 of their last 3 games but are coming into this one off of a loss in their last game which snapped a 2 game winning streak that they were on. Their 2 wins in that span came against the Las Vegas Raiders and the Pittsburgh Steelers while their loss was against the Los Angeles Chargers in their last game. Joe Burrow completed 24/40 passes for 300 yards, 1 touchdown pass and 2 interceptions. Joe Mixon led the team in rushing in that game with 54 yards and 1 touchdown on 19 carries while Burrow also ran in 1 TD on the ground as well. Tee Higgins had a nice day as he led the receivers with 138 yards and 1 touchdown on 9 receptions while Tyler Boyd had 85 yards on 5 receptions. Joe Bachie and Mike Hilton both led the defense in that game with 6 solo tackles and 3 assisted ones. Vonn Bell, Larry Ogunjobi, and Trey Hendrickson all led the defense in sacks in that game with 1 each while Chidobe Awuzie came up with the only interception in that one for them. They have scored 309 points in their 12 games this season averaging 25.8 PPG and they have allowed their opponents to score 226 points against them allowing 18.8 PPG. Their offense is averaging 325.9 YPG while their defense is allowing 319.2 YPG.
 
 

 

49ers vs Bengals Prediction

The Cin Bengals are coming into this game as a 1 point favorite with the current betting odds according to Draftkings Sportsbook. The Bengals are coming off of a bad loss against the Chargers that they lost by almost 20 points. They have been very inconsistent in their games this season, winning big against teams that they should not be beating by that much but then losing badly to teams that they should be beating. The 49ers are even on the season but they are not having the season that they were expecting and they have really been struggling to win games this year. Both teams are going to be looking to bounce back in this game after they each lost but the Bengals are a more talented team and less banged up coming into this game. The 49ers have been getting healthier recently, but the Bengals are at home here and are just the better team. The best bet to place in this game is on the Bengals to cover the spread and to win this game straight up on the moneyline. 
 
49ers Bengals Prediction:  Our NFL Pick for Sunday, December 12, 2021 (4:25 pm ET start time) is Bengals 28 49ers 21.
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NFL Betting Trends

 
San Francisco 49ers: 10-5 ATS as an underdog. 7-3 ATS as a road underdog. 14-8 ATS in road games. 17-6 ATS off an upset loss to a division rival as a favorite. 21-7 ATS off an upset loss as a road favorite. 
Cincinnati Bengals: 7-18 O/U off an upset loss by 10 points or more as a favorite. 3-15 O/U off an upset loss by 10 points or more as a home favorite. 4-8 O/U off a home loss. 23-31 O/U after allowing 35 points or more last game. 7-12 O/U after allowing 6 or more yards/play in their previous game.
 

Key Injuries

 
San Francisco 49ers:  E. Mitchell (RB) day-to-day - Head injury. Deebo Samuel (WR) day-to-day - Groin injury. M. Sanu Sr. (WR) Out indefinitely - Knee injury.
Cincinnati Bengals:  C. Awuzie (CB) day-to-day - Foot injury. L. Wilson (LB) Out indefinitely - Shoulder injury. T. Shelvin (DT) day-to-day - Knee injury.
 

Notable Quotes

 
"Our offense, we didn't really do anything in the second half. And it's hard to win in Seattle if you don't do anything in the second half." - George Kittle on their loss against the Seahawks in their last game.
 
 
"That was a sloppy game all-around. To get in a hole the way we did and the things that I did were unacceptable. We didn't deserve to win." - Zac Taylor on his team’s loss against the Chargers in their last game.
 
 

Starting Lineups

 
San Francisco 49ers
WR Brandon Aiyuk 
WR Samuel, Deebo 
TE Kittle, George
QB Garoppolo, Jimmy 
RB Elijah Mitchell
FB JUSZCZYK, KYLE 
 
Cincinnati Bengals
WR Chase, Ja'Marr 
WR Boyd, Tyler 
WR Higgins, Tee 
TE Uzomah, CJ 
QB Burrow, Joe 
RB Mixon, Joe  
 

Statistical Leaders

 
San Francisco 49ers
Passing: J. Garoppolo (2641)
Rushing: E. Mitchell (759)
Receiving: D. Samuel (1006)
Touchdowns: D. Samuel (10)
 
Cincinnati Bengals
Passing: J. Burrow (3135)
Rushing: J. Mixon (978)
Receiving: J. Chase (958)
Touchdowns: J. Mixon (14)
 
Coaches:
San Francisco 49ers: Kyle Shanahan (5th season)
Cincinnati Bengals:  Zac Taylor (3rd season)


Amedeus Mastrangelo

About the Author:

Amedeus Mastrangelo has been heavily wagering on all sports for years and plays just about everything, including sides, totals, favorites, underdogs, against the spread, alternative spreads, first half, second half, player props, and futures. The bottom line is, if Mastrangelo can see an edge in any way shape or form, then he's going to take advantage.

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