San Francisco 49ers vs Carolina Panthers Prediction, Preview and Odds - 10/09/2022

Game Time: 4:05 pm ET, Sunday, October 9, 2022

Venue:  Bank of America Stadium, Charlotte, NC

Where to Watch:  CBS

DraftKings:  Point Spread:  49ers -4.5, Panthers +4.5; Over/Under:  39 points

Bet365:  Point Spread:  49ers -5, Panthers +5; Over/Under:  39.5 points

BetMGM:  Point Spread:  49ers -5, Panthers +5; Over/Under:  39.5 points

 

San Francisco 49ers:  2-2 (1st place, NFC West)

Carolina Panthers:  1-3 (3rd place, NFC South)

 

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San Francisco 49ers:  won their last game at home against the Los Angeles Rams 24-9.

Carolina Panthers:  lost their last game at home against the Arizona Cardinals 26-16.

 

The 49ers are entering this game with a 2-2 record overall and they are playing their 3rd road game of the season here as they are 0-2 in their road games this year. Their offense is averaging 324.5 YPG and 17.8 PPG while their defense is allowing 234.5 YPG and 11.5 PPG against them. They won their last game at home against the LA Rams 24-9. Jimmy Garoppolo was the starting quarterback in that game and he completed 16/27 passes for 239 yards and 1 touchdown. Jeffrey Wilson led the team in rushing with 74 yards and 1 TD on 18 rushing attempts. Deebo Samuel led the team in receiving with 115 yards and 1 TD on 6 receptions. Dre Greenlaw led the defense in that game with 12 solo tackles and 3 assisted tackles. Samson Ebukam and Nick Bosa each led the defense in sacks with 2 while Talanoa Hufanga came away with the only interception for them in that one.

 

 

 

The Panthers are entering this game with a 1-3 record overall and they are playing their 4th home game of the season here as they are 1-2 in their home games this year. Their offense is averaging 262.3 YPG and 19.5 PPG while their defense is allowing 346 YPG and 21.3 PPG against them. They lost their last game at home against the Arizona Cardinals 26-16. Baker Mayfield was the starting QB in that game and he completed 22/36 passes for 197 yards, 1 touchdown, and 2 interceptions. Christian McCaffrey led the team in rushing with 27 yards on 8 carries. Christian McCaffrey led the team in receiving with 81 yards and 1 TD on 9 catches. Frankie Luvu led the defense in that game with 6 solo tackles and 5 assisted tackles. Brian Burns led the defense in sacks with 1 while Frankie Luvu came away with the only interception for them in that one.

 

The current betting odds have the 49ers listed as a 4.5 point favorite in this game according to Draftkings Sportsbook. The 49ers are only 2-2 this year but they have a very good team and could be one of the best in the NFL right now. Their season started off rocky as they were transitioning to Trey Lance at QB but a season ending injury for him has thrusted Jimmy Garoppolo back into the starting role and this team is back to looking like the team that went to the Super Bowl a few years ago and almost made it back last year. This defense is great and the offense has a lot of explosive weapons with a great coach in Kyle Shanahan making the calls too. The Panthers haven't looked good at all this year, they have some weapons on their offense and a very good defense too but the offense hasn't been able to get going with Baker Mayfield under center and it has been putting too much stress on the defense to keep them in games. The 49ers defense is just as good if not better and they are going to make it very difficult for Baker to move the ball here. The 49ers offense will find ways to score on this good defense too and this will just be another game in the win column for them. The best way to place a bet here is on the 49ers to cover the spread in this game.

 

49ers Panthers Prediction:  Our NFL Pick for Sunday, October 9, 2022 (4:05 pm ET start time) is 49ers 24 Panthers 14.

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San Francisco 49ers: 23-16 ATS as a road favorite of 3.5 to 7 points. 23-16 UNDER in all games. 14-8 UNDER in road games. 

Carolina Panthers: 15-22 ATS in all games. 5-14 ATS in home games. 34-19 UNDER in a home game where the total is between 38.5 and 42 points.

 

 

San Francisco 49ers:  E. Mitchell (RB) Out indefinitely - Knee. J. Ward (DB) Out indefinitely - Hamstring. C. Robinson (LB) Out indefinitely - Ankle.

Carolina Panthers:  L. Shenault Jr. (WR) day-to-day - Hamstring. S. Thomas-Oliver III (CB) day-to-day - Achilles. J. Chinn (S) day-to-day - Hamstring.

 

 

"It was just me and the ball out there. I just go out and break some tackles like I do all the time." - Deebo Samuel on his big plays after their win against the Rams in their last game.

 

 

"I don't have any thoughts about anything moving forward. We're going to go back and watch the tape and try to get these things corrected. Usually on Mondays I can give you better answers of what we will do going forward." - Matt Rhule after his team’s loss against the Cardinals in their last game.

 

 

 

WR Aiyuk, Brandon

WR Samuel, Deebo

WR Jennings, Jauan 

TE Kittle, George

QB GAROPPOLO, JIMMY

RB Wilson Jr., Jeff 

FB JUSZCZYK, KYLE 

 

WR Moore, DJ 

WR Anderson, Robbie

WR Smith, Shi 

TE Thomas, Ian

QB Mayfield, Baker 

RB McCaffrey, Christian 

 

 

Passing: J. Garoppolo (604)

Rushing: J. Wilson Jr. (255)

Receiving: D. Samuel (246)

Touchdowns: D. Samuel (2)

 

Passing: B. Mayfield (747)

Rushing: C. McCaffrey (270)

Receiving: R. Anderson (174)

Touchdowns: C. McCaffrey (2)

 

Coaches:

San Francisco 49ers: Kyle Shanahan (6th season)

Carolina Panthers: Matt Rhule (3rd season)