Game Time: 1:00 pm ET, Sunday, October 16, 2022
Venue: Mercedes Benz stadium Atlanta, Atlanta, GA
Where to Watch: Fox
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: 49ers -5, Falcons +5; Over/Under: 44.5 points
Bet365: Point Spread: 49ers -5.5, Falcons +5.5; Over/Under: 44.5 points
BetMGM: Point Spread: 49ers -5.5, Falcons +5.5; Over/Under: 44.5 points
Season Record
San Francisco 49ers: 3-2 (1st place, NFC West)
Atlanta Falcons: 2-3 (3rd place, NFC South)
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San Francisco 49ers: won their last game on the road against the Carolina Panthers 37-15.
Atlanta Falcons: lost their last game on the road against the Tampa Bay Buccaneers 21-15.
San Francisco 49ers vs Atlanta Falcons Preview and Analysis
The 49ers are entering this game with a 3-2 record overall and they are playing their 4th road game of the season here as they are 1-2 in their road games this year. Their offense is averaging 339 YPG and 21.6 PPG while their defense is allowing 249.2 YPG and 12.2 PPG against them. They won their last game on the road against the Carolina Panthers 37-15. Jimmy Garoppolo was the starting quarterback in that game and he completed 18/30 passes for 253 yards and 2 touchdowns. Jeffrey Wilson led the team in rushing with 120 yards and 1 TD on 17 rushing attempts. Brandon Aiyuk led the team in receiving with 58 yards on 3 receptions. Fred Warner led the defense in that game with 6 solo tackles and 3 assisted tackles. Demetrius Flannigan-Fowles, Talanoa Hufanga, Drake Jackson, and Charles Omenihu each led the defense in sacks with 1 while Emmanuel Moseley came away with the only interception for them in that one.
The Falcons are entering this game with a 2-3 record overall and they are playing their 3rd home game of the season here as they are 1-1 in their home games this year. Their offense is averaging 331.4 YPG and 23.6 PPG while their defense is allowing 393 YPG and 24.4 PPG against them. They lost their last game on the road against the Tampa Bay Buccaneers 21-15. Marcus Mariota was the starting QB in that game and he completed 14/25 passes for 147 yards and 1 touchdown. Marcus Mariota led the team in rushing with 61 yards on 7 carries. Olamide Zaccheaus led the team in receiving with 39 yards and 1 TD on 2 catches. Jaylinn Hawkins led the defense in that game with 7 solo tackles and 3 assisted tackles. No one on the defense recorded a sack for them and no one on the defense came away with an interception in that one.
49ers vs Falcons Prediction
The current betting odds have the 49ers listed as a 5 point favorite in this game according to Draftkings Sportsbook. The 49ers have looked really good in their games over the last few weeks. They got off to a rough start but this offense has looked a lot better with Jimmy Garoppolo leading the way. They have a great defense too and it will be hard for the Falcons to move the ball on them as they are missing so many weapons on offense. The Falcons got off to a great start but they still don't have a great team and they are going to start regressing in their coming games. The 49ers are the real deal and have a roster that could end up in the Super Bowl this season. The best way to place a bet here is on the 49ers to cover the spread in this game.
49ers Falcons Prediction: Our NFL Pick for Sunday, October 16, 2022 (1:00 pm ET start time) is 49ers 24 Falcons 14.
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NFL Betting Trends
San Francisco 49ers: 24-16 ATS as a road favorite of 3.5 to 7 points. 35-25 ATS in a road game where the total is between 42.5 and 45 points. 24-18 OVER against NFC South division opponents.
Atlanta Falcons: 9-20 ATS as a home underdog of 3.5 to 7 points. 5-12 ATS in home games. 32-14 OVER against NFC West division opponents.
Key Injuries
San Francisco 49ers: J. Willis (DL) Out indefinitely - Knee. E. Mitchell (RB) Out indefinitely - Knee. K. Davis (DL) Out indefinitely - Knee.
Atlanta Falcons: C. Patterson (RB) Out indefinitely - Knee. K. Pitts (TE) Ques Sun - Hamstring. D. London (WR) Ques Sun - Knee.
Notable Quotes
"I thought he played real well. He made some big plays, some big throws and didn't turn the ball over which was huge. That was real big emphasis coming into this game, so I was real happy with Jimmy." - Kyle Shanahan on Jimmy Garoppolo after his team’s win against the Panthers in their last game.
“From my vantage point it looked like it was a bad call, but that’s why you put the refs out there to make these calls. They pay these guys to make those calls. It looked bad on my standpoint, but I was in the back end.” - Casey Hayward after their loss against the Buccaneers in their last game.
Starting Lineups
San Francisco 49ers
WR Aiyuk, Brandon
WR Samuel, Deebo
WR Jennings, Jauan
TE Kittle, George
QB GAROPPOLO, JIMMY
RB Wilson Jr., Jeff
FB JUSZCZYK, KYLE
Atlanta Falcons
WR London, Drake
WR Hodge, KhaDarel
WR Zaccheaus, Olamide
TE Pitts, Kyle
QB Mariota, Marcus
RB Allgeier, Tyler
FB SMITH, KEITH
Statistical Leaders
San Francisco 49ers
Passing: J. Garoppolo (857)
Rushing: J. Wilson Jr. (375)
Receiving: D. Samuel (266)
Touchdowns: D. Samuel (3)
Atlanta Falcons
Passing: M. Mariota (926)
Rushing: C. Patterson (340)
Receiving: D. London (266)
Touchdowns: C. Patterson (3)
Coaches:
San Francisco 49ers: Kyle Shanahan (6th season)
Atlanta Falcons: Arthur Smith (2nd season)