Purdue Boilermakers vs Indiana Hoosiers Prediction, Picks and Game Preview - 01/27/2026

Game Time: 9:00 pm ET, Tuesday, January 27, 2026

Venue:  Simon Skjodt Assembly Hall, Bloomington, IN

Where to Watch:  Peacock

DraftKings:  Point Spread:  Purdue -3.5, Indiana +3.5; Over/Under:  151.5 points

Bet365:  Point Spread:  Purdue -3.5, Indiana +3.5; Over/Under:  151.5 points

BetMGM:  Point Spread:  Purdue -3.5, Indiana +3.5; Over/Under:  151.5 points

Purdue Boilermakers:  17-3 (7-2) (5th place, Big Ten)

Indiana Hoosiers:  13-7 (4-5) (11th place, Big Ten)

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Purdue Boilermakers:  3-2  last 5

Indiana Hoosiers:  1-4  last 5

Purdue is entering this game with a 17-3 record overall, a 7-2 record in conference games, and they are 4-1 in their road games this season where they will be in this game. They are coming off a loss against the Illinois Fighting Illini in their last game. Braden Smith led the team in points in that game with 27 while Trey Kaufman-Renn was next on the team with 12. Braden Smith led the team in assists with 12 in that game while Oscar Cluff led the team in rebounds with 4. They were 56.9% from the field, 36.8% from 3-point range, and 81.8% from the free throw line with their shooting in that game. Their offense is averaging 84 PPG and their defense is allowing their opponents to average 69.1 PPG against them. Purdue has an ATS record of 9-11 this season and their O/U record is 9-11.

Indiana is entering this game with a 13-7 record overall, a 4-5 conference record, and they are 10-2 in their home games this season where they will be in this game. They are coming off a win against the Rutgers Scarlet Knights in their last game. Lamar Wilkerson led the team in points in that game with 27 while Nick Dorn was next on the team with 23. Tucker DeVries led the team in assists with 6 in that game while Tucker DeVries and Sam Alexis each led the team in rebounds with 10. They were 50% from the field, 42.9% from 3-point range, and 100% from the free throw line with their shooting in that game. Their offense is averaging 81.2 PPG and their defense is allowing their opponents to average 69.4 PPG against them. Indiana has an ATS record of 10-10 this season and their O/U record is 9-11.

The current betting odds have Purdue listed as a 3.5 point favorite in this game according to Draftkings Sportsbook. Purdue has looked great in their games this season with their 17-3 record overall and their 7-2 conference record which has them right near the top of the Big Ten. They have been a good road team too with their 4-1 road record this year. Meanwhile, Indiana has looked good in their games this season with their 13-7 record overall, but their 4-5 conference record has them in the bottom half of the Big Ten. They have looked great on their home court though with their 10-2 home record this season. Indiana is off a big win over Rutgers in their last one, but that win snapped a losing streak as they are 1-4 in their last 5 games. They had a great start to the year with a weaker preseason schedule, but they have struggled a lot more in their Big Ten games and they definitely don't have the talent to compete with the teams at the top of the conference. Purdue was the number 1 team in the nation coming into the year and they have dropped a bit with some bad losses, but all of their losses have come against elite teams and Purdue is still one of the best teams in the nation. They are 3-2 in their last 5 games and they have looked good in conference play too, but they are off a home loss to Illinois in their last one and they have lost 2 games in a row now too, the other being on the road against UCLA. They were beaten at home in their last one by an Illinois team that has the potential to be one of the best teams in the nation, but Indiana doesn't and Purdue is going to be looking to bounce back in a big way against their biggest rival. Look for Purdue to bounce back and use this game against Indiana to get right. The best way to place a bet here is on Purdue to cover the spread in this game. 

Purdue Indiana Prediction:  Our NCAAB Pick for Tuesday, January 27, 2026 (9:00 pm ET start time) is Purdue 84 Indiana 73.

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Purdue Boilermakers: 6-3 ATS off an upset loss to a conference rival as a favorite. 10-4 ATS after a game where they made 55% of their shots or better. 25-16 ATS when playing against a good team (Win Pct. 60% to 80%). 9-4 OVER after a game where they made 55% of their shots or better.

Indiana Hoosiers: 2-6 ATS off a road win. 8-16 ATS off a win against a conference rival. 20-27 ATS vs. good free throw shooting teams - making 72% of their attempts or more. 6-3 OVER after 3 or more consecutive unders.

Purdue Boilermakers:  None.

Indiana Hoosiers:  J. Drake (G) Questionable - Undisclosed. J. Rayford (G) Out - Undisclosed. J. Harris (F) Questionable - Undisclosed.

"To me, even though [Wagler] gets 46 points, that's the game. If you look at our stats, you shoot 57% from the field, you shoot 37% from three, you shoot 82% from the line, you turn the ball over three times, that's a win. But then, all of a sudden, you go and say you got outrebounded by 14, and there lies the difference.” - Matt Painter after his team’s loss against Illinois in their last game. 

"Yeah, I thought our passing was pretty good. I thought the guys did a good job of knowing how Rutgers tries to defend, and you know, they're able to try to, you know, 'Okay, here's where they're really good, and here's where we can try to find some advantages,' and I thought they did a good job of finding those guys when those opportunities presented themselves as well." - Darian DeVries after his team’s win against Rutgers in their last game. 

O. Cluff 

C. Cox 

T. Kaufman-Renn 

F. Loyer 

B. Smith

S. Alexis 

T. Conerway 

T. DeVries 

C. Enright 

L. Wilkerson

PPG: Braden Smith (15.2)

APG: Braden Smith (9.3)

Reb/G: Trey Kaufman-Renn (8.6)

PPG: Lamar Wilkerson (19.4)

APG: Conor Enright (4.1)

Reb/G: Tucker DeVries (5)

Coaches:

Purdue Boilermakers: Matt Painter (21st season)

Indiana Hoosiers: Darian DeVries (1st season)