Purdue Boilermakers vs Alabama Crimson Tide Prediction, Picks and Game Preview - 11/13/2025

Game Time: 7:00 pm ET, Thursday, November 13, 2025

Venue:  Coleman Coliseum, Tuscaloosa, AL

Where to Watch:  ESPN2

DraftKings:  Point Spread:  Purdue +3.5, Alabama -3.5; Over/Under:  174.5 points

Bet365:  Point Spread:  Purdue +3.5, Alabama -3.5; Over/Under:  174.5 points

BetMGM:  Point Spread:  Purdue +3.5, Alabama -3.5; Over/Under:  174.5 points

Purdue Boilermakers:  2-0 (0-0) (13th place, Big Ten)

Alabama Crimson Tide:  2-0 (0-0) (11th place, SEC)

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Purdue Boilermakers:  2-0  last 2

Alabama Crimson Tide:  2-0  last 2

Purdue is entering this game with a 2-0 record overall, a 0-0 record in conference games, and they are 0-0 in their road games this season where they will be in this game. They are coming off a win against the Oakland Golden Grizzlies in their last game. Braden Smith led the team in points in that game with 20 while Fletcher Loyer was next on the team with 15. Braden Smith led the team in assists with 9 in that game while Oscar Cluff led the team in rebounds with 9. They were 47.1% from the field, 37.1% from 3-point range, and 66.7% from the free throw line with their shooting in that game. Their offense is averaging 84.5 PPG and their defense is allowing their opponents to average 64 PPG against them. Purdue has an ATS record of 0-2 this season and their O/U record is 1-1.

Alabama is entering this game with a 2-0 record overall, a 0-0 conference record, and they are 1-0 in their home games this season where they will be in this game. They are coming off a win against the St John’s Red Storm in their last game. Labaron Philon led the team in points in that game with 25 while Aden Holloway was next on the team with 21. Aden Holloway led the team in assists with 4 in that game while Amari Allen led the team in rebounds with 10. They were 48.1% from the field, 31.4% from 3-point range, and 63.6% from the free throw line with their shooting in that game. Their offense is averaging 97 PPG and their defense is allowing their opponents to average 79 PPG against them. Alabama has an ATS record of 1-1 this season and their O/U record is 1-1.

The current betting odds have Alabama listed as a 3.5 point favorite in this game according to Draftkings Sportsbook. Alabama has looked good in their games this season with their 2-0 record overall and they are ranked inside the top 25 teams in the nation. They are off a big road win over St John's in their last one, a team who was ranked higher entering the season, and that win is going to give Alabama a ton of momentum coming into this one. Meanwhile, Purdue has looked good in their games this season with their 2-0 record overall and they are ranked 2nd overall in the nation, but they haven't really played any good teams yet. They are off a 10 point win over Oakland in their last one and they struggled to pull away in that game, the game being tied at halftime. Now Purdue is playing their first road game of the season in a hostile environment and Alabama is still looking to prove themselves. They have a really tough schedule to start the season so they are going to bring their best effort in these kinds of games, and they have been one of the best teams in the nation over the last few seasons too. Alabama has a chance to make a big statement here with another win against a team ranked higher than they are, and they lost to Purdue last season so revenge is definitely on their mind too. The best way to place a bet here is on Alabama to cover the spread in this game. 

Purdue Alabama Prediction:  Our NCAAB Pick for Thursday, November 13, 2025 (7:00 pm ET start time) is Alabama 94 Purdue 86.

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Purdue Boilermakers: 20-12 ATS in non-conference games. 14-8 ATS after scoring 85 points or more. 5-2 OVER against SEC opponents. 36-23 OVER after 1 or more consecutive wins.

Alabama Crimson Tide: 1-3 ATS as a home favorite of 6 points or less or pick. 2-7 ATS in a home game where the total is 170 or more. 48-27 OVER in all games. 16-9 OVER when the total is 170 or more. 22-14 OVER in non-conference games.

Purdue Boilermakers:  T. Kaufman-Renn (F) Questionable - Undisclosed.

Alabama Crimson Tide:  K. Bristow (F) Doubtful - Ankle. J. Bethea (G) Out - Foot.

"We have to be good on all of the things that we work on: transition defense, taking good shots, and jamming the ball. I think those are the biggest things. The very fundamental, basic things we have to be really good at when we go out there." - Trey Kaufman-Renn on their upcoming game against Alabama.

"There’s levels to it. Some of these guys needed to figure it out. If you were grading it on a scale from one to 10, I think a lot of these guys thought they were giving max effort, and they were really giving us a six out of 10. They need to figure out how to get to a 10 out of 10. And I think we saw a lot more 10 out of 10s against St. John’s than we did against North Dakota." - Nate Oats on his team’s start to the season.

J. Benter 

O. Cluff 

C. Cox 

F. Loyer 

B. Smith

A. Allen 

T. Bowen 

H. Mallette 

L. Philon 

A. Sherrell

PPG: Fletcher Loyer (22.5)

APG: Braden Smith (10)

Reb/G: Oscar Cluff (9.5)

PPG: Labaron Philon Jr. (23.5)

APG: Labaron Philon Jr. (5.5)

Reb/G: Amari Allen (8.5)

Coaches:

Purdue Boilermakers: Matt Painter (21st season)

Alabama Crimson Tide: Nate Oats (7th season)