Portland Trail Blazers vs San Antonio Spurs Prediction, Preview and Odds - 04/08/2026

Game Time: 9:30 pm ET, Wednesday, April 8, 2026

Venue:  Frost Bank Center, San Antonio, TX 

Where to Watch:  ESPN

DraftKings:  Point Spread:  Trail Blazers +3.5, Spurs -3.5; Over/Under:  234.5 points

Bet365:  Point Spread:  Trail Blazers +3.5, Spurs -3.5; Over/Under:  234.5 points

BetMGM:  Point Spread:  Trail Blazers +3.5, Spurs -3.5; Over/Under:  234.5 points

Portland Trail Blazers:  40-39 (4th place, Northwest Division)

San Antonio Spurs:  60-19 (1st place, Southwest Division)

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Portland Trail Blazers:  7-3 last 10

San Antonio Spurs:  9-1 last 10

The Trail Blazers are entering this game with a 40-39 record overall this season and they are 18-22 in their road games this season where they will be in this game. They are entering this game off a loss against the Denver Nuggets. Toumani Camara led the team in points in that game with 30 while Deni Avdija was next on the team with 26 points. Jrue Holiday led the team in assists in that game with 11 while Donovan Clingan led the team in rebounds with 12. They were 47.2% from the field, 48.1% from 3-point range, and 82.1% from the free throw line with their shots in that game. Their offense is averaging 115.6 PPG and their defense is allowing their opponents to average 116.1 PPG against them. The Trail Blazers have an ATS record of 43-36 this season and their O/U record is 41-38.

The Spurs are entering this game with a 60-19 record overall this season and they are 30-7 in their home games this season where they will be in this game. They are entering this game off a win against the Philadelphia 76ers. Stephon Castle led the team in points in that game with 19 while Victor Wembanyama and Dylan Harper each were next on the team with 17 points. Stephon Castle led the team in assists in that game with 13 while Stephon Castle led the team in rebounds with 10. They were 49.4% from the field, 34.4% from 3-point range, and 72.7% from the free throw line with their shots in that game. Their offense is averaging 119.7 PPG and their defense is allowing their opponents to average 111.3 PPG against them. The Spurs have an ATS record of 44-34-2 this season and their O/U record is 35-45.

The current betting odds have the Trail Blazers listed as a 3.5 point underdog in this game according to Draftkings Sportsbook. The Trail Blazers have looked good in their games this season with their 40-39 record overall which has them right in the middle of the West. They haven't been a great road team though with their 18-22 road record this year. Meanwhile, the Spurs have looked great in their games this season with their 60-19 record overall which has them right at the top of the West with one of the best records in the entire NBA. They have looked great on their home court too with their 30-7 home record this season. The Spurs have been one of the best teams in the NBA all season and they haven't really been slowing down lately. They are off a win over the 76ers in their last one and they are 9-1 in their last 10 games. They still have a chance for the number 1 seed in the West, but they would pretty much have to win out with only 3 games left in the season. Wemby has also been dealing with some injury trouble lately and even left their last game early, so the Spurs could be more focused on resting their players for the playoffs at this point in the season. The Trail Blazers have also been rolling lately and they are definitely going to bring their best effort here to try and knock off one of the best in the league. They are off a loss to the Nuggets in their last one, but they took one of the best in the West to OT in that one and they are still 7-3 in their last 10 games. They have already clinched a spot in the play-in tournament, but they are only half a game behind the Clippers in the standings and they can still climb the standings, looking to avoid an extra game in the play-in tournament. The Trail Blazers have been showing a lot of fight lately so they are going to hang around in this game, and the Spurs might not be at full strength in this one too. The best way to place a bet here is on the Trail Blazers to cover the spread in this game. 

Trail Blazers Spurs Prediction:  Our NBA Pick for Wednesday, April 8, 2026 (9:30 pm ET start time) is Spurs 121 Trail Blazers 119.

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Portland Trail Blazers: 16-28 ATS versus good rebounding teams - outrebounding opponents by 3+ per game. 18-26 ATS on the road versus good offensive teams - scoring 116+ points/game. 4-7 ATS on the road after allowing 135 points or more. 11-4 UNDER versus good rebounding teams - outrebounding opponents by 3+ per game.

San Antonio Spurs: 23-9 ATS as a home favorite of 6 points or less. 27-13 ATS when playing against a team with a winning record. 28-16 ATS at home revenging a same season loss vs opponent. 33-22 UNDER when the total is greater than or equal to 230.

Portland Trail Blazers:  J. Grant (PF) Day To Day - Calf. V. Krejci (PG) Day To Day - Calf. S. Sharpe (SG) Out - Calf. D. Lillard (PG) Out For Season - Achilles.

San Antonio Spurs:  V. Wembanyama (C) Day To Day - Rib. D. Jones Garcia (SF) Out For Season - Ankle.

“This is a very experienced, vet team that has been in this situation 100 times or more. So, yes, it’s a learning experience. We’re going to have those games coming up — the Clippers, San Antonio, Sac, and then the play-in — and we’ve got to finish those games. This is where you learn from it. We just got schooled by one of, if not the, best team in the NBA right now.” - Tiago Splitter after his team’s loss against the Nuggets in their game on Monday. 

“No. I think it would be a positive that he felt like he could come back and he played the last four or five minutes in the [first] half. So, that’s a positive from my perspective.” - Mitch Johnson on the injury to Wemby after his team’s win against the 76ers in their game on Monday. 

PG Jrue Holiday

SG Toumani Camara

SF Deni Avdija

PF Matisse Thybulle

C Donovan Clingan

PG De'Aaron Fox

SG Stephon Castle

SF Devin Vassell

PF Julian Champagnie

C Victor Wembanyama

PPG: Deni Avdija (24)

APG: Deni Avdija (6.7)

Reb/G: Donovan Clingan (11.6)

PPG: Victor Wembanyama (24.8)

APG: Stephon Castle (7.4)

Reb/G: Victor Wembanyama (11.5)

Coaches:

Portland Trail Blazers: Tiago Splitter (1st season)

San Antonio Spurs: Mitch Johnson (2nd season)