by Rod Pearson
Friday, Nov 07, 2025
Game Time: 8:20 pm ET, Sunday, November 9, 2025
Venue: SoFi Stadium, Inglewood, CA
Where to Watch: NBC, Peacock
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Steelers +3, Chargers -3; Over/Under: 45.5 points
Bet365: Point Spread: Steelers +2.5, Chargers -2.5; Over/Under: 45 points
BetMGM: Point Spread: Steelers +2.5, Chargers -2.5; Over/Under: 45 points
Season Record
Pittsburgh Steelers: 5-3 (1st place, AFC North)
Los Angeles Chargers: 6-3 (2nd place, AFC West)
Do not miss out on our expert handicapper analysis! Kyle Hunter is on a HOT STREAK in the NFL on an 11-3 NFL RUN for +$7,650 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.
Recent Form
Pittsburgh Steelers: won their last game at home against the Indianapolis Colts 27-20.
Los Angeles Chargers: won their last game on the road against the Tennessee Titans 27-20.
Pittsburgh Steelers vs Los Angeles Chargers Preview and Analysis
The Steelers are entering this game with a 5-3 record overall and they have a 1-1 record in their divisional games too. They are 2-2 in their home games, 2-1 in their road games, and they are also 1-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Indianapolis Colts 27-20. Aaron Rodgers was the starting QB and he completed 25/35 passes for 203 passing yards, 1 touchdown, and 0 interceptions. Jaylen Warren led the team in rushing yards with 31 and 2 TDs. Calvin Austin III led the receivers with 56 receiving yards on 5 receptions. Payton Wilson led the defense in that game with 9 solo tackles and 4 assisted tackles while Alex Highsmith led the defense in sacks with 2. Payton Wilson, Joey Porter Jr., and Jack Sawyer each came away with 1 interception for them in that one.
The Chargers are entering this game with a 6-3 record overall and they have a 3-0 record in their divisional games too. They are 2-1 in their home games, 2-1-1 in their road games, and they are also 1-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Tennessee Titans 27-20. Justin Herbert was the starting QB and he completed 19/29 passes for 250 passing yards, 2 touchdowns, and 1 interception. Justin Herbert led the team in rushing yards with 57 and 1 TD. Oronde Gadsden II led the receivers with 68 receiving yards on 5 receptions. Derwin James Jr. led the defense in that game with 5 solo tackles and 3 assisted tackles while Odafe Oweh led the defense in sacks with 2. No one on the defense came away with an interception for them in that one.
Steelers vs Chargers Prediction
The current betting odds have the Chargers listed as a 3 point favorite in this game according to Draftkings Sportsbook. The Chargers have looked good in their games this season with their 6-3 record overall which has them right near the top of the AFC West. They are off a 27-20 win over the Titans in their last one and they will be looking to stay right on the tail of the Broncos who lead the division. Meanwhile, the Steelers have looked good in their games this season with their 5-3 record overall which has them right at the top of the AFC North. They are off a 27-20 win over the Colts in their last one and that was a big win for them as they needed to bounce back desperately, but they have been a really up and down team this year. They looked a lot better against the Colts last week, but their defense has been a big issue all year with the number of points they have been giving up. The Steelers also had multiple opportunities to really step on this division, but they squandered this opportunities with some bad losses and now they are starting to feel the pressure with the Ravens making a comeback. The Steelers haven't looked great from game to game this year and the Chargers have the talent on offense with Herbert to crush this up and down Steelers defense. The best way to place a bet here is on the Chargers to cover the spread in this game.
Steelers Chargers Prediction: Our NFL Pick for Sunday, November 9, 2025 (8:20 pm ET start time) is Chargers 31 Steelers 24.
Don't miss our champion handicappers free picks and expert football picks today. And if you enjoyed this Pittsburgh Steelers Los Angeles Chargers prediction, be sure to drop by every day for our weekly NFL predictions and previews.
NFL Betting Trends
Pittsburgh Steelers: 18-10 ATS in games where the line is +3 to -3. 9-3 ATS off an upset win as an underdog. 12-4 ATS after a game with a turnover margin of +2 or better. 9-3 UNDER off an upset win as an underdog. 7-3 UNDER vs. good passing teams averaging 235 or more passing yards/game.
Los Angeles Chargers: 3-9 ATS in a home game where the total is greater than or equal to 45.5. 2-6 ATS vs. poor passing defenses - allowing 235 or more passing yards/game. 2-9 ATS versus poor defensive teams - allowing 350 yards/game or more. 7-2 UNDER vs. poor passing defenses - allowing 235 or more passing yards/game.
Key Injuries
Pittsburgh Steelers: C. Heyward (DL) Injured - Rest. C. Heyward (TE) Injured - Knee. J. Peppers (S) Injured - Quadricep. C. Clark (S) Injured - Illness. J. Smith (TE) Injured - Rest. I. Seumalo (OG) Injured - Pectoral. A. Highsmith (LB) Injured - Ankle. S. Miller (WR) Injured - Finger. C. Holcomb (LB) Injured - Illness. C. Trice Jr. (CB) Injured - Hamstring. D. Washington (TE) Injured - Foot. W. Howard (QB) Injured - Right Hand.
Los Angeles Chargers: K. Lambert-Smith (WR) Injured - Hamstring. J. Harris (LS) Injured - Chest. K. Allen (WR) Injured - Rest. K. Mack (LB) Injured - Rest. B. Hart (OT) Injured - Knee. T. Jefferson (S) Injured - Hamstring. D. Hand (DL) Injured - Groin. M. Becton (OG) Injured - Knee. D. Leonard (CB) Injured - Knee. T. Still (CB) Injured - Knee.
Notable Quotes
“It's a fine line between drinking wine and squashing grapes.” - Mike Tomlin after his team’s win against the Colts in their last game.
“There’s no other ways I think that he can impress, you know? But then every time I think that, then he finds a way to, you know, it’s like another rung on the ladder of esteem. Yeah, he’s that guy. He’s that competitor.” - Jim Harbaugh on Justin Herbert after his team’s win against the Titans in their last game.
Starting Lineups
Pittsburgh Steelers
WR Metcalf, DK
WR Austin III, Calvin
TE Smith, Jonnu
TE Washington, Darnell
QB Rodgers, Aaron
RB Warren, Jaylen
Los Angeles Chargers
WR Johnston, Quentin
WR Allen, Keenan
WR McConkey, Ladd
TE Gadsden, Oronde
QB Herbert, Justin
RB Vidal, Kimani
FB Matlock, Scott
Statistical Leaders
Pittsburgh Steelers
Passing: Aaron Rodgers (1,692)
Rushing: Jaylen Warren (404)
Receiving: DK Metcalf (467)
Touchdowns: DK Metcalf (5)
Los Angeles Chargers
Passing: Justin Herbert (2,390)
Rushing: Omarion Hampton (314)
Receiving: Ladd McConkey (524)
Touchdowns: Quentin Johnston (6)
Coaches:
Pittsburgh Steelers: Mike Tomlin (19th season)
Los Angeles Chargers: Jim Harbaugh (2nd season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
