Philadelphia Phillies vs Washington Nationals Prediction, Preview and Odds - 06/24/2026

Game Time: 6:45 pm ET, Wednesday, June 24, 2026

Venue:  Nationals Park, Washington, DC

Where to Watch:  MLB TV

DraftKings:  Moneyline odds:  Phillies -131, Nationals +109; Over/Under:  9 runs

Bet365:  Moneyline odds:  Phillies -130, Nationals +110; Over/Under:  9 runs

BetMGM:  Moneyline odds:  Phillies -135, Nationals +110; Over/Under:  9 runs

Philadelphia Phillies:  42-36 (2nd place, NL East)

Washington Nationals:  41-38 (3rd place, NL East)

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Philadelphia Phillies:  5-5 last 10

Washington Nationals:  6-4 last 10

The Phillies are entering this series off a win and won their 3-game series against the New York Mets 2-1 in their last series. They enter this game with a 42-36 record overall and have a road record of 19-17. This is the 3rd game of a 4-game series with the Nationals on Wednesday with the 2nd game still to be played on Tuesday. The Phillies lost the series opener on Monday. Their offense ranks 25th in the MLB with a .693 OPS. Jesús Luzardo is their starting pitcher on Tuesday while Aaron Nola is making his start in this game on Wednesday. He is 3-4 with a 5.71 ERA this season. His team won 4 of their last 5 games this season with him making an appearance. In his last MLB regular season appearance, he allowed 2 ER, 2 HR, and 1 BB with 6 SO on 7 hits through 5 IP against the New York Mets.

The Nationals are entering this series off a loss and lost their 3-game series against the Tampa Bay Rays 2-1 in their last series. They enter this game with a 41-38 record overall and have a home record of 17-22. This is the 3rd game of a 4-game series with the Phillies on Wednesday with the 2nd game of this series still to be played on Tuesday. The Nationals won the 1st game of this series on Monday. Their offense ranks 4th in the MLB with a .744 OPS. Zack Littell is their starting pitcher on Tuesday while Miles Mikolas is making his start in this game on Wednesday. He is 2-6 with a 5.47 ERA this season. His team won 2 of their last 3 games this season with him making an appearance. In his last MLB regular season start, he allowed 5 earned runs, 2 homers, and 1 walk with 2 strikeouts on 9 hits through 6 innings pitched against the Tampa Bay Rays.

The current betting odds have the Phillies listed as a favorite in this game according to Draftkings Sportsbook. The Phillies have looked good in their games this season with their 42-36 record overall which has them right near the top of the NL East. They have been a good road team too with their 19-17 road record this year. Meanwhile, the Nationals have looked good in their games this season with their 41-38 record overall, but that record has them right near the bottom of the NL East. They haven't looked great in their own ballpark too with their 17-22 home record this season. The Nationals are 6-4 in their last 10 games and have been getting hot lately while the Phillies are 5-5 in their last 10 games, but the Phillies have the better pitching matchup in this one and they can take advantage of that. The Phillies are going with Nola in this one and he hasn't looked great this season. He is 3-4 with a 5.71 ERA, but lately he has looked a lot better and hasn't been giving up many runs. He only gave up 2 earned runs in his last start and even his team has been having a ton of success with him lately, winning 4 of their last 5 games with him starting. The Nationals are going with Mikolas in this one and he hasn't looked good this season. He is 2-6 with a 5.47 ERA and he has been giving up a ton of runs all year. His team has been having success with him lately, winning 2 of their last 3 games with him starting, but he did give up 5 earned runs in his last start and that has been a common theme for him all year. Look for the Phillies to take advantage of this pitching matchup with Nola pitching a lot better now, and the Nationals have been a worse team at home this season too. The best way to place a bet here is on the Phillies to win this game. 

Phillies Nationals Prediction:  Our MLB Pick for Wednesday, June 24, 2026 (6:45 pm ET start time) is Phillies 7 Nationals 3.

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Philadelphia Phillies: 102-100 (-14.2 units) on the moneyline in road games. 82-83 (-22.8 units) on the moneyline when the money line is -100 to -150. 71-57 (-5.2 units) on the moneyline against division opponents. 33-25 OVER vs. a starting pitcher whose lasts less than 5 innings per start.

Washington Nationals: 178-226 (+9.1 units) on the moneyline in all games. 141-185 (+22.8 units) on the moneyline as an underdog of +100 or higher. 22-16 (+9.2 units) on the moneyline vs. a starting pitcher who gives up 1 or more HR's/start. 26-11 OVER in home games.

Philadelphia Phillies:  B. Keller (RP) Fifteen Day IL - Forearm. A. Garcia (RF) Sixty Day IL - Lat. 

Washington Nationals:  M. Kranick (RP) Sixty Day IL - Elbow. J. Irvin (SP) Fifteen Day IL - Shoulder. K. Waldichuk (SP) Sixty Day IL - Forearm. J. Gray (SP) Sixty Day IL - Elbow. D. Herz (SP) Sixty Day IL - Elbow. T. Williams (SP) Sixty Day IL - Elbow.

“A lot of just the mix and match for us. We didn’t seem to do enough with him. He got ahead in counts, threw strikes, a variety of basically breaking balls for the lefties, kept the righties off balance for the most part.” - Don Mattingly after his team’s loss against the Nationals in their game on Monday. 

“It’s a tough look for righties and lefties. That over-the-top high slot with a good carry on the fastball. Then that changeup he was throwing, he was throwing a lot. He had a lot of success on it. Even when hitters are recognizing it out of the hand, it’s just a funky look. It’s slower than you think, even if you see it, and a lot of them continue to ride, and you think they’re going to drop. It’s just a tough at-bat, no matter if you’re right-handed or left-handed.” - Blake Butera on Alan Rangel after his team’s win against the Phillies in their game on Monday. 

Trea Turner (R) SS

Kyle Schwarber (L) DH

Bryce Harper (L) 1B

Alec Bohm (R) 3B

Edmundo Sosa (R) LF

Brandon Marsh (L) RF

Derek Hill (R) CF

Bryson Stott (L) 2B

Rafael Marchán (S) C

James Wood (L) RF

Curtis Mead (R) 3B

Dylan Crews (R) LF

CJ Abrams (L) SS

Jacob Young (R) CF

Daylen Lile (L) DH

Keibert Ruiz (S) C

Luis García Jr. (L) 1B

Nasim Nuñez (S) 2B

Batting Average:  Brandon Marsh (.311)

Hits:  Brandon Marsh (82)

Home Runs:  Kyle Schwarber (29)

RBI:  Kyle Schwarber (52)

Stolen Bases:  Trea Turner (15)

Wins:  Cristopher Sánchez (9)

Saves:  Jhoan Duran (18)

ERA:  Bryse Wilson (0.00)

Batting Average:  Keibert Ruiz (.288)

Hits:  CJ Abrams (82)

Home Runs:  James Wood (20)

RBI:  CJ Abrams (57)

Stolen Bases:  Nasim Nuñez (29)

Wins:  Foster Griffin (8)

Saves:  Gus Varland (6)

ERA:  Julian Fernández (2.25)

Managers:

Philadelphia Phillies: Don Mattingly (Interim)

Washington Nationals: Blake Butera (1st season)