Philadelphia Phillies vs Washington Nationals Prediction, Preview and Odds - 06/23/2026

Game Time: 6:45 pm ET, Tuesday, June 23, 2026

Venue:  Nationals Park, Washington, DC

Where to Watch:  MLB TV

DraftKings:  Moneyline odds:  Phillies -165, Nationals +135; Over/Under:  8.5 runs

Bet365:  Moneyline odds:  Phillies -168, Nationals +139; Over/Under:  8.5 runs

BetMGM:  Moneyline odds:  Phillies -165, Nationals +140; Over/Under:  8.5 runs

Philadelphia Phillies:  42-35 (2nd place, NL East)

Washington Nationals:  40-38 (4th place, NL East)

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Philadelphia Phillies:  6-4 last 10

Washington Nationals:  5-5 last 10

The Phillies are entering this series off a win and won their 3-game series against the New York Mets 2-1 in their last series. They enter this game with a 42-35 record overall and have a road record of 19-16. This is the 2nd game of a 4-game series with the Nationals on Tuesday with the series opener still to be played on Monday. Their offense ranks 25th in the MLB with a .696 OPS. Tim Mayza is their starting pitcher on Monday while Jesús Luzardo is making his start in this game on Tuesday. He is 6-4 with a 4.20 ERA this season. His team won their last 5 straight games this season with him making an appearance. In his last MLB regular season appearance, he allowed 2 ER, 1 HR, and 2 BB with 9 SO on 5 hits through 7 IP against the Miami Marlins.

The Nationals are entering this series off a loss and lost their 3-game series against the Tampa Bay Rays 2-1 in their last series. They enter this game with a 40-38 record overall and have a home record of 16-22. This is the 2nd game of a 4-game series with the Phillies on Tuesday with the 1st game of this series still to be played on Monday. Their offense ranks 5th in the MLB with a .741 OPS. Foster Griffin is their starting pitcher on Monday while Zack Littell is making his start in this game on Tuesday. He is 6-6 with a 5.45 ERA this season. His team lost their last 2 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 4 earned runs, 4 homers, and 2 walks with 2 strikeouts on 7 hits through 5 innings pitched against the Kansas City Royals.

The current betting odds have the Phillies listed as a favorite in this game according to Draftkings Sportsbook. The Phillies have looked good in their games this season with their 42-35 record overall which has them right near the top of the NL East. They have been a good road team too with their 19-16 road record this year. Meanwhile, the Nationals have looked good in their games this season with their 40-38 record overall, but that record has them right near the bottom of the NL East. They haven't looked great in their own ballpark too with their 16-22 home record this season. The Nationals haven't looked bad lately, but they have been really up and down all season and now they are 5-5 in their last 10 games after losing their last series to the Rays. The Phillies have been rolling over the last month after a bad start to the season and they are now 6-4 in their last 10 games, coming off another series win over the Mets. Luzardo is on the mound for the Phillies in this one and he hasn't looked great this season. He is 6-4 with a 4.20 ERA, but lately he has looked a lot better. He only gave up 2 earned runs in his last start which is starting to become a common theme, and his team has been having a ton of success with him lately, winning 5 games in a row now with him as the starter. The Nationals are going with Littell in this one and he hasn't looked great this season. He is 6-6 with a 5.45 ERA and he has been giving up quite a few runs lately. He gave up 4 earned runs in his last start which has been a common theme for him and even the team has lost 2 games in a row now with him starting. The Nationals do have the better offense this season, but they haven't looked nearly as good at home this year while the Phillies have been getting hot lately and can take advantage of this pitching matchup. The best way to place a bet here is on the Phillies to win this game. 

Phillies Nationals Prediction:  Our MLB Pick for Tuesday, June 23, 2026 (6:45 pm ET start time) is Phillies 6 Nationals 4.

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Philadelphia Phillies: 236-174 (+9.3 units) on the moneyline in all games. 195-116 (+19.5 units) on the moneyline as a favorite of -110 or higher. 167-105 (+30.6 units) on the moneyline against right-handed starters. 33-25 OVER vs. a starting pitcher whose lasts less than 5 innings per start.

Washington Nationals: 87-115 (-15.3 units) on the moneyline in home games. 30-52 (-9.3 units) on the moneyline as a home underdog of +125 to +175. 34-48 (-9.4 units) on the moneyline at home when the total is 8 to 8.5. 26-10 OVER in home games.

Philadelphia Phillies:  B. Keller (RP) Fifteen Day IL - Forearm. A. Garcia (RF) Sixty Day IL - Lat. K. Backhus (RP) Fifteen Day IL - Elbow.

Washington Nationals:  J. Young (CF) Day To Day - Upper Body. M. Kranick (RP) Sixty Day IL - Elbow. J. Irvin (SP) Fifteen Day IL - Shoulder. K. Waldichuk (SP) Sixty Day IL - Forearm. J. Gray (SP) Sixty Day IL - Elbow. D. Herz (SP) Sixty Day IL - Elbow. T. Williams (SP) Sixty Day IL - Elbow.

“I thought we had great at-bats the whole series. I thought the pitching was good. As a whole, I thought we played great in this series.” - Bryce Harper after their series against the Mets.

“We could leave here frustrated, losing that one-run game today and having a chance to leave here winning two out of three [games]. We’ve got the Phillies coming to town, who are ahead of us right now, and they’re playing good baseball. We know we’ve got another challenge in front of us. It’s not going to get easier as we go. You can either back down or you can take this as fun ... and let’s go.’’ - Blake Butera after his team’s loss against the Rays in their game on Sunday. 

Trea Turner (R) SS

Kyle Schwarber (L) DH

Bryce Harper (L) 1B

Alec Bohm (R) 3B

Edmundo Sosa (R) LF

Brandon Marsh (L) RF

J.T. Realmuto (R) C

Derek Hill (R) CF

Bryson Stott (L) 2B

James Wood (L) RF

Luis García Jr. (L) 1B

Curtis Mead (R) 3B

CJ Abrams (L) SS

Daylen Lile (L) LF

Dylan Crews (R) CF

José Tena (L) DH

Drew Millas (S) C

Nasim Nuñez (S) 2B

Batting Average:  Brandon Marsh (.310)

Hits:  Brandon Marsh (81)

Home Runs:  Kyle Schwarber (29)

RBI:  Kyle Schwarber (52)

Stolen Bases:  Trea Turner (15)

Wins:  Cristopher Sánchez (9)

Saves:  Jhoan Duran (18)

ERA:  Bryse Wilson (0.00)

Batting Average:  Joey Wiemer (.286)

Hits:  CJ Abrams (81)

Home Runs:  James Wood (20)

RBI:  CJ Abrams (57)

Stolen Bases:  Nasim Nuñez (28)

Wins:  Foster Griffin (7)

Saves:  Gus Varland (6)

ERA:  Julian Fernández (2.25)

Managers:

Philadelphia Phillies: Don Mattingly (Interim)

Washington Nationals: Blake Butera (1st season)