Philadelphia Phillies vs St Louis Cardinals Prediction, Preview and Odds - 08/11/2026

Game Time: 7:45 pm ET, Tuesday, August 11, 2026

Venue:  Busch Stadium, St. Louis, MO

Where to Watch:  MLB TV

DraftKings:  Moneyline odds:  Phillies -167, Cardinals +137; Over/Under:  8 runs

Bet365:  Moneyline odds:  Phillies -165, Cardinals +135; Over/Under:  8 runs

BetMGM:  Moneyline odds:  Phillies -165, Cardinals +140; Over/Under:  8 runs

Philadelphia Phillies:  63-56 (2nd place, NL East)

St Louis Cardinals:  59-59 (3rd place, NL Central)

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Philadelphia Phillies:  6-4 last 10

St Louis Cardinals:  5-5 last 10

The Phillies are entering this series off a win and lost their 3-game series against the Toronto Blue Jays 2-1 in their last series. They enter this game with a 63-56 record overall and have a road record of 31-26. This is the 2nd game of a 3-game series with the Cardinals on Tuesday with the series opener still to be played on Monday. Their offense ranks 21st in the MLB with a .709 OPS. Rookie pitcher Andrew Painter is their starting pitcher on Monday while Cristopher Sánchez is making his start in this game on Tuesday. He is 15-4 with a 2.65 ERA this season. His team won their last 5 straight games this season with him making an appearance. In his last MLB regular season appearance, he allowed 2 ER, 1 HR, and 2 BB with 6 SO on 6 hits through 5 IP against the Washington Nationals.

The Cardinals are entering this series off a win and won their 3-game series against the Colorado Rockies 2-1 in their last series. They enter this game with a 59-59 record overall and have a home record of 30-33. This is the 2nd game of a 3-game series with the Phillies on Tuesday with the 1st game of this series still to be played on Monday. Their offense ranks 25th in the MLB with a .696 OPS. Hunter Dobbins is their starting pitcher on Monday while Andre Pallante is making his start in this game on Tuesday. He is 12-6 with a 3.63 ERA this season. His team won 2 of their last 3 games this season with him making an appearance. In his last MLB regular season start, he allowed 1 earned run, 0 homers, and 3 walks with 4 strikeouts on 3 hits through 5.1 innings pitched against the New York Yankees.

The current betting odds have the Phillies listed as a favorite in this game according to Draftkings Sportsbook. The Phillies have looked good in their games this season with their 63-56 record overall which has them right near the top of the NL East. They have been a good road team too with their 31-26 road record this year. Meanwhile, the Cardinals have looked good in their games this season with their 59-59 record overall which has them right in the middle of the NL Central. They haven't looked great in their own ballpark though with their 30-33 home record this season. The Cardinals are 5-5 in their last 10 games and they definitely haven't been at their best lately, sliding down the Wild Card race over the last few weeks. The Phillies have been rolling lately though, now 6-4 in their last 10 games, and their offense has looked a lot better too. The Phillies are going with Sanchez in this one and he has looked great this season. He is 15-4 with a 2.65 ERA and he has been their ace. He is coming off another great start giving up 2 earned runs which has been a common theme for him all season and the team has had a ton of success with him lately too, winning 5 games in a row now with him starting. The Cardinals are going with Pallante in this one and he has looked good this season. He is 12-6 with a 3.63 ERA and he has been their ace this year. The team has won 2 of their last 3 games with him starting and he only gave up 1 earned run in his last start which has been a common theme. As good as he has been this year, the Phillies still have the edge with Sanchez being the more reliable starter and the Phillies also have the stronger offense to lean on too. Look for the Phillies to take advantage of this pitching matchup and continue rolling in this series against an up and down Cardinals team that hasn't been great at home. The best way to place a bet here is on the Phillies to win this game. 

Phillies Cardinals Prediction:  Our MLB Pick for Tuesday, August 11, 2026 (7:45 pm ET start time) is Phillies 2 Cardinals 1.

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Philadelphia Phillies: 42-42 (-9.8 units) on the moneyline against NL Central opponents. 114-109 (-13.7 units) on the moneyline in road games. 92-89 (-20 units) on the moneyline when the money line is -100 to -150. 55-34 UNDER on the road with a money line of -100 to -150.

St Louis Cardinals: 116-122 (+24.3 units) on the moneyline as an underdog of +100 or higher. 67-58 (+9.1 units) on the moneyline against left-handed starters. 104-110 (+8 units) on the moneyline when playing against a team with a winning record. 16-6 UNDER as a home underdog of +125 or more.

Philadelphia Phillies:  D. Hill (CF) Day To Day - Shoulder. A. Nola (SP) Day To Day - Knee. A. Painter (SP) Day To Day - Hamstring. T. Banks (RP) Sixty Day IL - Forearm. R. Marchan (C) Ten Day IL - Knee. B. Keller (RP) Sixty Day IL - Elbow. J. Rojas (CF) Sixty Day IL - Elbow. A. Garcia (RF) Sixty Day IL - Lat.

St Louis Cardinals:  M. Rajcic (SP) Sixty Day IL - Elbow. R. Urias (3B) Sixty Day IL - Elbow.

"A little Utley Philly toughness today. It's the kind of game that you're going to have to win. Every win is good." - Don Mattingly after his team’s win against the Blue Jays in their game on Sunday. 

“Being on go is important. You don’t try to just grind at-bats for the sake of grinding. You don’t want chase, you want to get him in the zone and you want to be super selective. But when it’s where you’re hunting, let it eat. Those guys did a good job of that.” - Oliver Marmol after his team’s win against the Rockies in their game on Sunday. 

Kyle Schwarber (L) DH

Trea Turner (R) SS

Bryce Harper (L) RF

Luis Arraez (L) 2B

J.T. Realmuto (R) C

Bryson Stott (L) 3B

Brandon Marsh (L) LF

Alec Bohm (R) 1B

Justin Crawford (L) CF

JJ Wetherholt (L) 2B

Iván Herrera (R) DH

Alec Burleson (L) 1B

Jordan Walker (R) RF

Jimmy Crooks (L) C

Masyn Winn (R) SS

Nathan Church (L) CF

José Fermín (R) 3B

Bryan Torres (L) LF

Batting Average:  Bryan De La Cruz (.346)

Hits:  Trea Turner (119)

Home Runs:  Kyle Schwarber (35)

RBI:  Bryce Harper (71)

Stolen Bases:  Bryson Stott (22)

Wins:  Cristopher Sánchez (15)

Saves:  Jhoan Duran (25)

ERA:  Bryse Wilson (0.00)

Batting Average:  Jordan Walker (.285)

Hits:  Jordan Walker (127)

Home Runs:  Jordan Walker (23)

RBI:  Jordan Walker (83)

Stolen Bases:  Jordan Walker (14)

Wins:  Andre Pallante (12)

Saves:  Riley O'Brien (29)

ERA:  Caleb Ferguson (0.00)

Managers:

Philadelphia Phillies: Don Mattingly (Interim)

St Louis Cardinals: Oliver Marmol (5th season)