Game Time: 8:15 pm ET, Monday, December 8, 2025
Venue: SoFi Stadium, Inglewood, CA
Where to Watch: ESPN, ABC
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Eagles -2.5, Chargers +2.5; Over/Under: 41.5 points
Bet365: Point Spread: Eagles -2.5, Chargers +2.5; Over/Under: 41 points
BetMGM: Point Spread: Eagles -2.5, Chargers +2.5; Over/Under: 41 points
Season Record
Philadelphia Eagles: 8-4 (1st place, NFC East)
Los Angeles Chargers: 8-4 (2nd place, AFC West)
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Philadelphia Eagles: lost their last game at home against the Chicago Bears 24-15.
Los Angeles Chargers: won their last game at home against the Las Vegas Raiders 31-14.
Philadelphia Eagles vs Los Angeles Chargers Preview and Analysis
The Eagles are entering this game with an 8-4 record overall and they have a 2-2 record in their divisional games too. They are 4-2 in their home games, 4-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the Chicago Bears 24-15. Jalen Hurts was the starting QB and he completed 19/34 passes for 230 passing yards, 2 touchdowns, and 1 interception. Saquon Barkley led the team in rushing yards with 56. A. J. Brown led the receivers with 132 receiving yards on 10 receptions and 2 TDs. Reed Blankenship led the defense in that game with 8 solo tackles and 6 assisted tackles while Jalen Carter and Nolan Smith Jr. each led the defense in sacks with 1. Jalyx Hunt came away with the only interception for them in that one.
The Chargers are entering this game with an 8-4 record overall and they have a 4-0 record in their divisional games too. They are 4-2 in their home games, 3-2 in their road games, and they are also 1-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Las Vegas Raiders 31-14. Justin Herbert was the starting QB and he completed 15/20 passes for 151 passing yards, 2 touchdowns, and 1 interception. Kimani Vidal led the team in rushing yards with 126 and 1 TD. Ladd McConkey led the receivers with 39 receiving yards on 4 receptions and 1 TD. Denzel Perryman led the defense in that game with 6 solo tackles and 1 assisted tackle while Tuli Tuipulotu led the defense in sacks with 2. Tony Jefferson came away with the only interception for them in that one.
Eagles vs Chargers Prediction
The current betting odds have the Eagles listed as a 2.5 point favorite in this game according to Draftkings Sportsbook. The Eagles have looked really good in their games this season with their 8-4 record overall which has them right at the top of the NFC East. They have been a good road team too with their 4-2 road record this year. Meanwhile, the Chargers have looked really good in their games this season with their 8-4 record overall which has them right near the top of the AFC West. They have looked good on their home field too with their 4-2 home record this year. The Chargers are off a 31-14 win over the Raiders in their last one, but they have been dealing with a ton of injuries lately and Justin Herbert picked up an injury in that game too. He should be able to play in this one, but he is still banged up and playing against one of the best defenses in the NFL. The Eagles are off a 24-15 loss to the Bears in their last one and they have lost 2 games in a row now, but they will be looking to bounce back. The offense hasn't looked great this season, but they still have a ton of talent to work with and a defense that can keep this Chargers offense at bay. The Eagles are going to be desperate to win this game and stop the bleeding, and they can take advantage of the injuries that the Chargers are dealing with. The best way to place a bet here is on the Eagles to cover the spread in this game.
Eagles Chargers Prediction: Our NFL Pick for Monday, December 8, 2025 (8:15 pm ET start time) is Eagles 24 Chargers 20.
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NFL Betting Trends
Philadelphia Eagles: 17-4 ATS in games where the line is +3 to -3. 9-4 ATS in non-conference games. 15-8 ATS after playing a game at home. 13-7 UNDER versus good offensive teams - averaging 5.65 yards/play or more. 6-1 UNDER when playing on Monday night.
Los Angeles Chargers: 0-3 ATS against NFC East division opponents. 0-4 ATS as a home underdog of 7 points or less. 3-7 ATS versus poor rushing defenses - allowing 4.5 rushing yards/carry or more. 9-3 UNDER in non-conference games. 6-2 UNDER off a win against a division rival.
Key Injuries
Philadelphia Eagles: L. Johnson (OT) Injured - Foot. J. Phillips (LB) Injured - Concussion. Z. Baun (LB) Injured - Hand. M. Epps (S) Injured - Shoulder. J. Dotson (WR) Injured - Toe. X. Gipson (WR) Injured - Shoulder. J. Carter (DL) Injured - Shoulder. M. Hinton (OT) Injured - Back.
Los Angeles Chargers: B. Dupree (LB) Injured - Rest. D. Hand (DL) Injured - Illness. J. Herbert (QB) Injured - Hand. T. Fisk (TE) Injured - Ankle. J. Salyer (OG) Injured - Shoulder. H. Haskins (RB) Injured - Hamstring. O. Ogbonnia (DL) Injured - Elbow. T. Pipkins III (OG) Injured - Back. Q. Johnston (WR) Injured - Shoulder. O. Hampton (RB) Injured - Ankle.
Notable Quotes
“I have confidence in him. I have confidence in this team. I have confidence in us when we’re collaborative. I have a lot of confidence when we have an identity, so I think that’s the first thing that we have to establish that we’ve talked about.” - Jalen Hurts after their loss against the Bears in their last game.
“He's as tough as they come.” - Jim Harbaugh on Justin Herbert after his team’s win against the Raiders in their last game.
Starting Lineups
Philadelphia Eagles
WR Brown, A.J.
WR Smith, DeVonta
WR Dotson, Jahan
TE Goedert, Dallas
QB Hurts, Jalen
RB Barkley, Saquon
Los Angeles Chargers
WR Johnston, Quentin
WR Allen, Keenan
WR McConkey, Ladd
TE Gadsden, Oronde
QB Herbert, Justin
RB Vidal, Kimani
FB Matlock, Scott
Statistical Leaders
Philadelphia Eagles
Passing: Jalen Hurts (2,514)
Rushing: Saquon Barkley (740)
Receiving: DeVonta Smith (802)
Touchdowns: Jalen Hurts (8)
Los Angeles Chargers
Passing: Justin Herbert (2,842)
Rushing: Kimani Vidal (543)
Receiving: Ladd McConkey (683)
Touchdowns: Quentin Johnston (7)
Coaches:
Philadelphia Eagles: Nick Sirianni (5th season)
Los Angeles Chargers: Jim Harbaugh (2nd season)