Philadelphia 76ers vs Chicago Bulls Prediction, Preview and Odds - 11/04/2025

Game Time: 8:00 pm ET, Tuesday, November 4, 2025

Venue:  United Center, Chicago, IL

Where to Watch:  NBCS-P+, CHSN

DraftKings:  Point Spread:  76ers +1.5, Bulls -1.5; Over/Under:  239.5 points

Bet365:  Point Spread:  76ers +1.5, Bulls -1.5; Over/Under:  239.5 points

BetMGM:  Point Spread:  76ers +1.5, Bulls -1.5; Over/Under:  239.5 points

Philadelphia 76ers:  5-1 (1st place, Atlantic Division)

Chicago Bulls:  5-1 (1st place, Central Division)

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Philadelphia 76ers:  5-1 last 6

Chicago Bulls:  5-1 last 6

The 76ers are entering this game with a 5-1 record overall this season and they are 3-0 in their road games this season where they will be in this game. They are entering this game off a win against the Brooklyn Nets. Kelly Oubre Jr. led the team in points in that game with 29 while Tyrese Maxey was next on the team with 26 points. Quentin Grimes led the team in assists in that game with 13 while Trendon Watford led the team in rebounds with 9. They were 52.1% from the field, 37.5% from 3-point range, and 82.4% from the free throw line with their shots in that game. Their offense is averaging 125.7 PPG and their defense is allowing their opponents to average 118.2 PPG against them. The 76ers have an ATS record of 5-1 this season and their O/U record is 5-1.

The Bulls are entering this game with a 5-1 record overall this season and they are 4-0 in their home games this season where they will be in this game. They are entering this game off a loss against the New York Knicks. Josh Giddey led the team in points in that game with 23 while Nikola Vučević was next on the team with 17 points. Josh Giddey led the team in assists in that game with 12 while Nikola Vučević led the team in rebounds with 14. They were 48.4% from the field, 42.5% from 3-point range, and 81.8% from the free throw line with their shots in that game. Their offense is averaging 121.7 PPG and their defense is allowing their opponents to average 116.3 PPG against them. The Bulls have an ATS record of 5-1 this season and their O/U record is 4-2.

The current betting odds have the Bulls listed as a 1.5 point favorite in this game according to Draftkings Sportsbook. The Bulls have looked great in their games this season with their 5-1 record overall which has them right near the top of the East with one of the best records in the NBA. They have been red hot to start the season and they have looked great on their home court with their 4-0 home record this year. Meanwhile, the 76ers have looked great in their games this season with their 5-1 record overall which has them right at the top of the East with one of the best records in the NBA. They have also been a great road team so far with their 3-0 road record this season. They are coming off a big win over the Nets in their last one and that was a bounce back win for them after losing to the Celtics the game before, but the 76ers have also played in a lot of tight games this season. They are off a blow out win over the Nets, but the Nets are one of the worst teams in the NBA and a majority of their wins so far have been by 5 points or less. The Bulls have been rolling in their games though, a majority of their wins coming by double digits. They are off a double digit loss to the Knicks in their last one, but that was their first loss of the season and they will be looking to bounce back at home. The Bulls will bring their best effort to bounce back at home against a 76ers team that has had some tight games this year. The best way to place a bet here is on the Bulls to cover the spread in this game. 

76ers Bulls Prediction:  Our NBA Pick for Tuesday, November 4, 2025 (8:00 pm ET start time) is Bulls 117  76ers 112.

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Philadelphia 76ers: 3-11 ATS off a win against a division rival. 24-31 ATS versus poor defensive teams - allowing 116+ points/game. 14-4 OVER when playing against a top-level team (Win Pct. > 70%). 31-20 OVER versus good teams - outscoring their opponents by 3+ points/game.

Chicago Bulls: 24-18 ATS off a road loss. 6-3 ATS versus good foul drawing teams - attempting 27 free throws/game or more. 32-22 ATS versus poor defensive teams - allowing 116+ points/game. 25-17 OVER off a road loss. 18-9 OVER versus teams who average 7 or less steals/game on the season.

Philadelphia 76ers:  J. Embiid (C) Day To Day - Rest. D. Barlow (PF) Day To Day - Elbow. P. George (PF) Day To Day - Knee. J. McCain (SG) Out - Thumb.

Chicago Bulls:  A. Dosunmu (SG) Day To Day - Illness. C. White (SG) Out - Calf. Z. Collins (PF) Out - Wrist.

"Well, it was really good for him tonight. I think the biggest thing was those guys—they executed the game plan offensively of what we're trying to do, right? And that's really important. It was to create space and move the basketball game, and then attack some of that space, and then you got to make the players in front of you. It's either a shot or it's a dump off or a kick out. They were doing it." - Nick Nurse after his team’s win against the Nets in their game on Sunday.

‘‘I think the front office was very transparent going all the way back to the draft. Noa was one of the guys we went through [in the draft process]. You don’t know how the draft is going to play out or who is going to be there, but one of the things that we talked about prior to [his selection] was that he was going to be a development piece. He was not going to be a guy that was going to be immediately in the rotation. There needed to be a plan for him.’’ - Billy Donovan on rookie draft pick Noa Essengue.

PG Tyrese Maxey

SG VJ Edgecombe

SF Kelly Oubre Jr.

PF Jabari Walker

C Joel Embiid

PG Josh Giddey

SG Kevin Huerter

SF Isaac Okoro

PF Matas Buzelis

C Nikola Vucevic

PPG: Tyrese Maxey (33.7)

APG: Tyrese Maxey (9)

Reb/G: Andre Drummond (6.7)

PPG: Josh Giddey (22.2)

APG: Josh Giddey (8.7)

Reb/G: Nikola Vucevic (12.3)

Coaches:

Philadelphia 76ers: Nick Nurse (3rd season)

Chicago Bulls: Billy Donovan (6th season)