Oregon Ducks vs Washington Huskies Prediction, Picks and Game Preview - 11/29/2025

by Rod Pearson

Wednesday, Nov 26, 2025
Game Time: 3:30 pm ET, Saturday, November 29, 2025
Venue:  Husky Stadium, Seattle, WA
Where to Watch:  CBS


Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  Oregon -7, Washington +7; Over/Under:  51.5 points
Bet365:  Point Spread:  Oregon -6.5, Washington +6.5; Over/Under:  51 points
BetMGM:  Point Spread:  Oregon -6.5, Washington +6.5; Over/Under:  51.5 points

Season Record

Oregon Ducks:  10-1 (7-1) (3rd place, Big Ten)
Washington Huskies:  8-3 (5-3) (6th place, Big Ten)

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Recent Form
Oregon Ducks:  won their last game at home against the USC Trojans 42-27.
Washington Huskies:  won their last game on the road against the UCLA Bruins 48-14.


Oregon Ducks vs Washington Huskies Preview and Analysis


Oregon is entering this game with a 10-1 record overall and they have a 7-1 record in their conference games too. They are 6-1 in their home games, 4-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against USC 42-27. Dante Moore was the starting QB and he completed 22/30 passes for 257 passing yards, 2 touchdowns, and 1 interception. Noah Whittington led the team in rushing yards with 104 and 1 TD. Kenyon Sadiq led the receivers with 72 receiving yards on 6 receptions and 2 TDs. Bryce Boettcher led the defense in that game with 4 solo tackles and 9 assisted tackles while Matayo Uiagalelei led the defense in sacks with 1. Jadon Canady and Ify Obidegwu each came away with 1 interception for them in that one.
 
 
 
Washington is entering this game with an 8-3 record overall and they have a 5-3 record in their conference games too. They are 5-1 in their home games, 3-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against UCLA 48-14. Demond Williams Jr. was the starting QB and he completed 17/26 passes for 213 passing yards, 2 touchdowns, and 1 interception. Adam Mohammed led the team in rushing yards with 108. Dezmen Roebuck led the receivers with 96 receiving yards on 7 receptions and 1 TD. Alex McLaughlin led the defense in that game with 4 solo tackles and 3 assisted tackles while Bryce Butler led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.


Oregon vs Washington Prediction

The current betting odds have Oregon listed as a 7 point favorite in this game according to Draftkings Sportsbook. Oregon has looked great in their games this season with their 10-1 record overall and their 7-1 conference record which has them right near the top of the Big Ten. They have been a great road team too with their 4-0 road record this season. Meanwhile, Washington has looked good in their games this season with their 8-3 record overall and their 5-3 conference record which has them in the top half of the Big Ten. They have looked great on their home field too with their 5-1 home record this season. They are off a 48-14 win over UCLA in their last one and they have looked really good against bad opponents this year, but they have also crumbled when given the opportunity to make a statement. They have been in big games this year, but they have fallen short in every one. Now they have a chance to potentially spoil Oregon's season and playoff hopes with a win, but this is a game that has been trouble for Oregon in the past and they aren't going to be blindsided by it. Oregon is off a 42-27 win over USC in their last one and that win should give them some momentum entering this game. They could still make the CFP with a loss, but they don't have a strong resume and it is a very crowded field with 2 loss teams this year so Oregon is going to bring their best effort to make sure they don't get tripped up here. Washington is a good team, but Oregon is a great team and they will show why they deserve to be in the CFP. The best way to place a bet here is on Oregon to cover the spread in this game. 

Oregon Washington Prediction:  Our NCAAF Pick for Saturday, November 29, 2025 (3:30 pm ET start time) is Oregon 35 Washington 24.
Don't miss our champion handicappers free picks and expert football picks today. And if you enjoyed this Oregon Ducks Washington Huskies prediction, be sure to drop by every day for our weekly NCAAF predictions and previews.

NCAAF Betting Trends


Oregon Ducks: 24-14 ATS in all lined games. 8-4 ATS as a road favorite. 8-4 ATS off a home win against a conference rival. 5-0 UNDER as a favorite of 3.5 to 10 points. 

Washington Huskies: 4-8 ATS as an underdog. 6-11 ATS off a win against a conference rival. 2-9 ATS vs. good defensive teams who give up 17 or less points/game. 9-3 UNDER as an underdog. 9-4 UNDER after a win by 17 or more points.

Key Injuries


Oregon Ducks:  G. Wilson (OG) Questionable - Undisclosed. J. Limar (RB) Questionable - Undisclosed. D. Moore (WR) Questionable - Knee. D. Riggs (RB) Questionable - Undisclosed. J. Ressler (WR) Questionable - Undisclosed. S. Laulea (CB) Questionable - Undisclosed. D. Gresham (WR) Questionable - Undisclosed. G. Bryant Jr. (WR) Questionable - Ankle. T. Gray (DL) Questionable - Undisclosed. K. Kasper (WR) Out - Undisclosed. M. Hughes (RB) Out - Redshirt. B. Boulton (OG) Out - Undisclosed. E. Stewart (WR) Out - Knee. T. McNutt (CB) Out - Leg.

Washington Huskies:  Q. Carr (RB) Questionable - Undisclosed. D. Azzopardi (OG) Questionable - Undisclosed. M. McCree (OG) Questionable - Undisclosed. I. Ward (DL) Questionable - Undisclosed. R. Vines-Bright (WR) Questionable - Undisclosed. A. Parker (DL) Out - Undisclosed. C. Christian (S) Out - Undisclosed. R. Williams (WR) Out - Collarbone. K. Eldridge (TE) Out - Undisclosed. B. Al-Uqdah (LB) Out - Undisclosed. R. Davis II (DL) Out - Undisclosed. C. Crowell (TE) Out - Undisclosed. D. McCutcheon (S) Out - Undisclosed. R. Wright II (S) Out - Undisclosed.

Notable Quotes


“We know they were going to throw some punches, right? That's an explosive offense. They hit some big plays on us. I was really pleased with the guys being able to hit the reset button and saying, `Let's go again.'” - Dan Lanning after his team’s win against USC in their last game. 


“We made the game big. We let them know we're going to the Rose Bowl, we're going to go win this thing. These guys didn't think it was too big for them. They're just getting better and better and better.” - Jedd Fisch after his team’s win against UCLA in their last game. 


Starting Lineups


Oregon Ducks
WR Benson, Malik
WR Moore, Dakorien
WR Bryant Jr., Gary
TE Sadiq, Kenyon
QB Moore, Dante
RB Whittington, Noah

Washington Huskies
WR Boston, Denzel
WR Roebuck, Dezmen
WR Vines-Bright, Raiden
TE DeGraaf, Decker
QB Williams Jr., Demond
RB Coleman, Jonah

Statistical Leaders


Oregon Ducks
Passing: Dante Moore (2,447)
Rushing: Noah Whittington (727)
Receiving: Kenyon Sadiq (479)
Touchdowns: Jordon Davison (13)

Washington Huskies
Passing: Demond Williams Jr. (2,721)
Rushing: Jonah Coleman (651)
Receiving: Denzel Boston (730)
Touchdowns: Jonah Coleman (16)

Coaches:
Oregon Ducks: Dan Lanning (4th season)
Washington Huskies: Jedd Fisch (2nd season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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