Oregon Ducks vs Ohio State Buckeyes Prediction, Picks and Game Preview - 11/07/2026

Game Time: 3:30 pm ET, Saturday, November 7, 2026

Venue:  Ohio Stadium, Columbus, OH

Where to Watch:  CBS

DraftKings:  Point Spread:  Oregon +7.5, Ohio State -7.5; Over/Under:  46.5 points

Bet365:  Point Spread:  Oregon +7.5, Ohio State -7.5; Over/Under:  46.5 points

BetMGM:  Point Spread:  Oregon +7.5, Ohio State -7.5; Over/Under:  46.5 points

Oregon Ducks:  5-3 (3-2) (8th place, Big Ten)

Ohio State Buckeyes:  6-2 (4-1) (3rd place, Big Ten)

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Oregon Ducks:  won their last game at home against the Northwestern Wildcats 34-26.

Ohio State Buckeyes:  lost their last game on the road against the USC Trojans 30-18.

Oregon is entering this game with a 5-3 record overall and they have a 3-2 record in their conference games too. They are 4-1 in their home games, 1-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against Northwestern 34-26. Dylan Raiola was the starting QB and he completed 22/31 passes for 336 passing yards, 3 touchdowns, and 0 interceptions. Brandon Smith led the team in rushing yards with 82 and 1 TD. Dakorien Moore led the receivers with 128 receiving yards on 7 receptions and 2 TDs. Devin Jackson led the defense in that game with 9 tackles while D'Antre Robinson and Nasir Wyatt each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

 

 

 

Ohio State is entering this game with a 6-2 record overall and they have a 4-1 record in their conference games too. They are 4-0 in their home games, 2-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against USC 30-18. Luke Fahey was the starting QB and he completed 21/38 passes for 260 passing yards, 1 touchdown, and 0 interceptions. Bo Jackson led the team in rushing yards with 121. Jeremiah Smith led the receivers with 83 receiving yards on 10 receptions and 1 TD. Payton Pierce led the defense in that game with 6 tackles while Jermaine Mathews Jr. led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

The current betting odds have Ohio State listed as a 7.5 point favorite in this game according to Draftkings Sportsbook. Ohio State has looked good in their games this season with their 6-2 record overall and their 4-1 conference record which has them right near the top of the Big Ten. They have looked great on their home field too with their 4-0 home record this season. Meanwhile, Oregon has looked good in their games this season with their 4-3 record overall and their 3-2 conference record which has them in the top half of the Big Ten. They haven't been a great road team though with their 1-2 road record this year. Oregon is coming off a 34-26 win over Northwestern in their last one and they looked a lot better than they did the week before. They have been really up and down since losing their starting QB for the season, but they were also having trouble before he got injured. This has been a bit of a disaster season for Oregon with all of the players that they had returning after being one of the best teams in the nation last season. They have shown some flashes of greatness, but they haven't looked that great overall and this is still a really tough game for them, even with Ohio State being down to their backup QB. Ohio State is coming off a 30-18 loss to USC and they will be looking to bounce back after that bad loss. They were down right away against USC and never really got themselves back into the game, but that was also a really tough situation for their QB in his 1st start on the road out West. Now they are going to be in the comfort of their own home and they still have one of the most talented rosters in the nation. Oregon is surprisingly ranked in the CFP rankings, but this is a great opportunity for Ohio State to make a statement at home with their backup QB and really put the final nail in the coffin of this Oregon season. The best way to place a bet here is on Ohio State to cover the spread in this game. 

Oregon Ohio State Prediction:  Our NCAAF Pick for Saturday, November 7, 2026 (3:30 pm ET start time) is Ohio State 24 Oregon 13.

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Oregon Ducks: 5-8 ATS versus good rushing defenses - allowing 3.25 rushing yards/carry or less. 7-4 UNDER as a road underdog of 7.5 to 14 points. 8-5 1H UNDER in road lined games. 

Ohio State Buckeyes: 13-6 ATS as a home favorite. 16-9 ATS against conference opponents. 14-7 ATS when playing against a team with a winning record. 10-5 UNDER when the total is between 42.5 and 49. 17-8 UNDER against conference opponents.

Oregon Ducks:  E. Stewart (WR) Questionable - Undisclosed. I. Hooks (WR) Out - Undisclosed. D. Gresham (WR) Questionable - Neck. S. Price (RB) Questionable - Undisclosed. A. Flowers (CB) Out - Undisclosed. J. McClellan (WR) Out - Foot.

Ohio State Buckeyes:  J. Jackson (RB) Out - Foot. B. Jackson (RB) Questionable - Shoulder. J. Sayin (QB) Out - Arm. A. Valerio-Hudson (WR) Questionable - Undisclosed. T. Rogers (RB) Questionable - Undisclosed. B. Christian (TE) Questionable - Undisclosed.

“I feel like that’s the closest we’ve been to a complete performance. That being said, there’s a lot of things we can still do better.” - Dan Lanning after his team’s win against Northwestern in their last game. 

“At the end of the day, as a team, we weren’t able to play well enough to support a young freshman quarterback who has his first start on the road like this.” - Ryan Day after his team’s loss against USC in their last game.  

WR Moore, Dakorien

WR Hampton, Messiah

WR Stewart, Evan

TE Johnson, Jamari

QB Raiola, Dylan

RB Davison, Jordon

WR Smith, Jeremiah

WR McCuin, Devin

WR Inniss, Brandon

TE Roberts, Nate

QB Fahey, Luke

RB Jackson, Bo

Passing: Dylan Raiola (1,097)

Rushing: Jordon Davison (439)

Receiving: Dakorien Moore (545)

Touchdowns: Jordon Davison (7)

Passing: Julian Sayin (2,007)

Rushing: Bo Jackson (637)

Receiving: Jeremiah Smith (1,067)

Touchdowns: Jeremiah Smith (13)

Coaches:

Oregon Ducks: Dan Lanning (5th season)

Ohio State Buckeyes: Ryan Day (9th season)