Oregon Ducks vs Iowa Hawkeyes Prediction, Picks and Game Preview - 11/08/2025

Game Time: 3:30 pm ET, Saturday, November 8, 2025

Venue:  Kinnick Stadium, Iowa City, IA

Where to Watch:  CBS

DraftKings:  Point Spread:  Oregon -6.5, Iowa +6.5; Over/Under:  40.5 points

Bet365:  Point Spread:  Oregon -6, Iowa +6; Over/Under:  40.5 points

BetMGM:  Point Spread:  Oregon -6, Iowa +6; Over/Under:  40.5 points

Oregon Ducks:  7-1 (4-1) (5th place, Big Ten)

Iowa Hawkeyes:  6-2 (4-1) (4th place, Big Ten)

Do not miss out on our expert handicapper analysis! Big Al McMordie is on a HOT STREAK in college football on a 14-6 CFB RUN for +$7,510 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.

Oregon Ducks:  won their last game at home against the Wisconsin Badgers 21-7.

Iowa Hawkeyes:  won their last game at home against the Minnesota Golden Gophers 41-3.

Oregon is entering this game with a 7-1 record overall and they have a 4-1 record in their conference games too. They are 4-1 in their home games, 3-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against Wisconsin 21-7. Dante Moore was the starting QB and he completed 9/15 passes for 86 passing yards, 0 touchdowns, and 0 interceptions. Jordon Davison led the team in rushing yards with 102 and 2 TDs. Dakorien Moore led the receivers with 45 receiving yards on 3 receptions. Bryce Boettcher led the defense in that game with 4 solo tackles and 2 assisted tackles while Theran Johnson led the defense in sacks with 1. Daylen Austin came away with the only interception for them in that one.

 

 

 

Iowa is entering this game with a 6-2 record overall and they have a 4-1 record in their conference games too. They are 4-1 in their home games, 2-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against Minnesota 41-3. Mark Gronowski was the starting QB and he completed 12/19 passes for 135 passing yards, 1 touchdown, and 0 interceptions. Kamari Moulton led the team in rushing yards with 75. Kaden Wetjen led the receivers with 49 receiving yards on 3 receptions. Xavier Nwankpa led the defense in that game with 5 solo tackles and 1 assisted tackle while Aaron Graves led the defense in sacks with 2. Cam Buffington, Zach Lutmer, and TJ Hall each came away with 1 interception for them in that one.

The current betting odds have Oregon listed as a 6.5 point favorite in this game according to Draftkings Sportsbook. Oregon has looked really good in their games this season with their 7-1 record overall and their 4-1 conference record which has them right near the top of the Big Ten. Their only loss was at home to Indiana who is the 2nd ranked team in the nation, but they have a chance to make a statement here with a big road win. Meanwhile, Iowa has looked really good in their games this season with their 6-2 record overall and their 4-1 conference record which has them right near the top of the Big Ten. They aren't ranked inside the top 25 in the AP poll, but they are ranked inside the top 20 in the CFP rankings and have been making a case for themselves as a playoff team. They do have a loss to Iowa State in a tight one, but they also have a really tight loss to Indiana in a 1 score game too. They have a chance to make a statement with a big upset win, but Oregon will also be looking to make their own statement and they do have a lot more talent on their team. Iowa has a really good defense that doesn't give up much so it isn't going to be easy for this Oregon offense, but Oregon also has a great defense to keep this Iowa offense at bay. Iowa is off a 41-3 win over Minnesota in their last one, but their offense hasn't really looked that great all season and Oregon has a big advantage in that area. Both defenses are going to keep this a tighter game at first, but Oregon's much better offense should be enough for them to get the job done on the road. The best way to place a bet here is on Oregon to cover the spread in this game. 

Oregon Iowa Prediction:  Our NCAAF Pick for Saturday, November 8, 2025 (3:30 pm ET start time) is Oregon 21 Iowa 10.

Don't miss our champion handicappers free picks and expert football picks today. And if you enjoyed this Oregon Ducks Iowa Hawkeyes prediction, be sure to drop by every day for our weekly NCAAF predictions and previews.

Oregon Ducks: 22-13 ATS in all lined games. 8-3 ATS as a road favorite. 12-6 ATS after allowing 14 points or less last game. 7-3 ATS when playing against a top-level team (Win Pct. > 75%). 20-12 UNDER as a favorite. 9-5 UNDER versus good rushing defenses - allowing 120 rushing yards/game or less.

Iowa Hawkeyes: 3-7 ATS after a win by 17 or more points. 2-7 ATS after a game with a turnover margin of +2 or better. 8-1 UNDER as an underdog. 11-5 UNDER off a win against a conference rival. 13-6 UNDER after allowing 14 points or less last game. 6-2 UNDER vs. good offensive  teams - scoring 31 or more points/game.

Oregon Ducks:  D. Riggs (RB) Questionable - Undisclosed. J. Ressler (WR) Questionable - Undisclosed. S. Laulea (CB) Questionable - Undisclosed. D. Gresham (WR) Questionable - Undisclosed. J. Limar (RB) Out - Undisclosed. K. Kasper (WR) Out - Undisclosed. M. Hughes (RB) Out - Redshirt. B. Boulton (OG) Out - Undisclosed. E. Stewart (WR) Out - Knee. T. McNutt (CB) Out - Leg.

Iowa Hawkeyes:  L. Gaffney (DL) Questionable - Undisclosed. B. Doll (RB) Questionable - Undisclosed. J. Buie (WR) Questionable - Undisclosed. D. Howard (WR) Questionable - Undisclosed. D. Vonnahme (TE) Out - Undisclosed. A. Ostrenga (TE) Out - Undisclosed.

“I think the most important thing about Jordon is how much he's able to handle. He's a really really smart player. We do a lot formationally, we have a lot of different plays. For him to be able to execute those plays at a really high level, when the call comes in, he's doing his job.” - Dan Lanning after his team’s win against Wisconsin in their last game. 

“We were getting the ball to our playmakers. I really liked the rhythm we had in the first half.” - Mark Gronowski after their win against Minnesota in their last game. 

WR Benson, Malik

WR Moore, Dakorien

WR Bryant Jr., Gary

TE Sadiq, Kenyon

QB Moore, Dante

RB Whittington, Noah

WR Phillips, Sam

WR Gill, Jacob

WR Anderson, Seth 

TE Ortwerth, Zach

QB Gronowski, Mark

RB Washington Jr., Terrell

Passing: Dante Moore (1,772)

Rushing: Noah Whittington (433)

Receiving: Dakorien Moore (443)

Touchdowns: Jordon Davison (10)

Passing: Mark Gronowski (946)

Rushing: Kamari Moulton (435)

Receiving: Sam Phillips (204)

Touchdowns: Mark Gronowski (11)

Coaches:

Oregon Ducks: Dan Lanning (4th season)

Iowa Hawkeyes: Kirk Ferentz (27th season)