Oklahoma Sooners vs Alabama Crimson Tide Prediction, Picks and Game Preview - 11/15/2025

Game Time: 3:30 pm ET, Saturday, November 15, 2025

Venue:  Saban Field at Bryant-Denny Stadium, Tuscaloosa, AL

Where to Watch:  ABC

DraftKings:  Point Spread:  Oklahoma +6, Alabama -6; Over/Under:  45.5 points

Bet365:  Point Spread:  Oklahoma +6, Alabama -6; Over/Under:  46 points

BetMGM:  Point Spread:  Oklahoma +6, Alabama -6; Over/Under:  45.5 points

Oklahoma Sooners:  7-2 (3-2) (7th place, SEC)

Alabama Crimson Tide:  8-1 (6-0) (2nd place, SEC)

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Oklahoma Sooners:  won their last game on the road against the Tennessee Volunteers 33-27.

Alabama Crimson Tide:  won their last game at home against the LSU Tigers 20-9.

Oklahoma is entering this game with a 7-2 record overall and they have a 3-2 record in their conference games too. They are 4-1 in their home games, 3-0 in their road games, and they are also 0-1 in their neutral site games this season, but they will be on the road for this game. They won their last game against Tennessee 33-27. John Mateer was the starting QB and he completed 19/29 passes for 159 passing yards, 0 touchdowns, and 1 interception. Xavier Robinson led the team in rushing yards with 115 and 1 TD. Isaiah Sategna led the receivers with 68 receiving yards on 6 receptions. Owen Heinecke led the defense in that game with 6 solo tackles and 7 assisted tackles while Owen Heinecke, Danny Okoye, and R Mason Thomas each led the defense in sacks with 1. Robert Spears-Jennings and Peyton Bowen each came away with 1 interception for them in that one.

 

 

 

Alabama is entering this game with an 8-1 record overall and they have a 6-0 record in their conference games too. They are 5-0 in their home games, 3-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against LSU 20-9. Ty Simpson was the starting QB and he completed 21/35 passes for 277 passing yards, 1 touchdown, and 0 interceptions. Daniel Hill led the team in rushing yards with 21 and 1 TD. Germie Bernard led the receivers with 79 receiving yards on 3 receptions. Deontae Lawson led the defense in that game with 5 solo tackles and 4 assisted tackles while Yhonzae Pierre led the defense in sacks with 2. No one on the defense came away with an interception for them in that one.

The current betting odds have Oklahoma listed as a 6 point underdog in this game according to Draftkings Sportsbook. Oklahoma has looked really good in their games this season with their 7-2 record overall and their 3-2 conference record which has them higher in the SEC. They have been a great road team this year too with their 3-0 road record. Meanwhile, Alabama has looked great in their games this season with their 8-1 record overall and their 6-1 conference record which has them right near the top of the SEC. They have also looked great on their home field with their 5-0 home record. Alabama has had an interesting season, starting the year with a loss to Florida State who has been terrible for most of the year, and now they have won 8 games in a row. They look like one of the teams to beat in the SEC this year, but lately they haven't looked as good. They are off a 20-9 win at home over LSU in their last one, a week after struggling to beat South Carolina in a game where they needed a comeback win, and they haven't really been blowing teams out all year either. Oklahoma really saved their season in their last one with a big road win over Tennessee and now they are playing with their season on the line here since a 3rd loss will likely keep them out of the CFP. They are coming out of their bye week with extra time to prepare so they are going to bring their best effort in this road game, and they still have one of the best defenses in the SEC to lean on. Even if Oklahoma loses this game, they have the defense to keep this a close one with Alabama not really running any of their opponents out of the building in their games. The best way to place a bet here is on Oklahoma to cover the spread in this game. 

Oklahoma Alabama Prediction:  Our NCAAF Pick for Saturday, November 15, 2025 (3:30 pm ET start time) is Alabama 23 Oklahoma 20.

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Oklahoma Sooners: 3-8 ATS off a win against a conference rival. 4-7 ATS when playing against a top-level team (Win Pct. > 75%). 1-5 ATS after a bye week. 7-4 OVER off a win against a conference rival. 3-0 OVER as a road underdog of 7 points or less.

Alabama Crimson Tide: 14-4 ATS as a home favorite. 15-8 ATS against conference opponents. 11-3 ATS when playing against a top-level team (Win Pct. > 75%). 10-2 OVER when the total is between 42.5 and 49. 6-3 OVER off a home win against a conference rival.

Oklahoma Sooners:  J. Taylor (OG) Questionable - Undisclosed. T. Tatum (RB) Questionable - Undisclosed. D. Simmons (OG) Questionable - Undisclosed. J. Sexton (OG) Questionable - Undisclosed. K. Lewis (WR) Questionable - Undisclosed. K. Dolby (CB) Questionable - Undisclosed. J. Barnes (RB) Questionable - Undisclosed. K. McKinzie (LB) Questionable - Undisclosed. T. Everett (OG) Out - Undisclosed.

Alabama Crimson Tide:  Q. Russaw (LB) Questionable - Leg. J. Latham (LB) Questionable - Neck. D. Kirkpatrick Jr. (CB) Questionable - Unknown. C. Jones (LB) Questionable - Undisclosed. J. Beaman (DL) Out - Lower Body.

“Our guys matched (Tennessee's) physicality, and then some. The pile constantly went in our direction. All those piles that fall forward add up to a lot.” - Brent Venables after his team’s win against Tennessee in their last game. 

“I feel like the defense has been pretty solid. There’s less of the explosive plays and guys are fitting their gaps. We missed a few opportunities with the ball on the ground or in the air. I like the way the defense is playing and they’ll go back to work tomorrow.” - Kalen DeBoer after his team’s win against LSU in their last game. 

WR Lewis, Keontez

WR Burks, Deion

WR Sategna III, Isaiah

TE Kanak, Jaren

QB Mateer, John

RB Blaylock, Tory

WR Horton, Isaiah

WR Bernard, Germie

WR Williams, Ryan

TE Lewis Jr., Danny

TE Cuevas, Josh

QB Simpson, Ty

RB Miller, Jam

Passing: John Mateer (1,949)

Rushing: Tory Blaylock (401)

Receiving: Isaiah Sategna III (692)

Touchdowns: John Mateer (6)

Passing: Ty Simpson (2,461)

Rushing: Jam Miller (321)

Receiving: Germie Bernard (605)

Touchdowns: Germie Bernard (8)

Coaches:

Oklahoma Sooners: Brent Venables (4th season)

Alabama Crimson Tide: Kalen DeBoer (2nd season)