Oklahoma City Thunder vs Milwaukee Bucks Prediction, Preview and Odds - 01/21/2026

Game Time: 9:30 pm ET, Wednesday, January 21, 2026

Venue:  Fiserv Forum, Milwaukee, WI 

Where to Watch:  ESPN

DraftKings:  Point Spread:  Thunder -10, Bucks +10; Over/Under:  226.5 points

Bet365:  Point Spread:  Thunder -10, Bucks +10; Over/Under:  226.5 points

BetMGM:  Point Spread:  Thunder -10, Bucks +10; Over/Under:  226.5 points

Oklahoma City Thunder:  36-8 (1st place, Northwest Division)

Milwaukee Bucks:  18-24 (4th place, Central Division)

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Oklahoma City Thunder:  7-3 last 10

Milwaukee Bucks:  5-5 last 10

The Thunder are entering this game with a 36-8 record overall this season and they are 16-5 in their road games this season where they will be in this game. They are entering this game off a win against the Cleveland Cavaliers. Shai Gilgeous-Alexander led the team in points in that game with 30 while Chet Holmgren was next on the team with 28 points. Ajay Mitchell led the team in assists in that game with 9 while Chet Holmgren led the team in rebounds with 8. They were 55.6% from the field, 48.9% from 3-point range, and 65% from the free throw line with their shots in that game. Their offense is averaging 121.4 PPG and their defense is allowing their opponents to average 108 PPG against them. The Thunder have an ATS record of 22-22 this season and their O/U record is 22-22.

The Bucks are entering this game with an 18-24 record overall this season and they are 9-10 in their home games this season where they will be in this game. They are entering this game off a win against the Atlanta Hawks. Giannis Antetokounmpo led the team in points in that game with 21 while Bobby Portis was next on the team with 19 points. Kevin Porter Jr. led the team in assists in that game with 7 while Giannis Antetokounmpo led the team in rebounds with 17. They were 49.4% from the field, 44.4% from 3-point range, and 72% from the free throw line with their shots in that game. Their offense is averaging 112.4 PPG and their defense is allowing their opponents to average 115.6 PPG against them. The Bucks have an ATS record of 19-23 this season and their O/U record is 17-25.

The current betting odds have the Thunder listed as a 10 point favorite in this game according to Draftkings Sportsbook. The Thunder have looked great in their games this season with their 36-8 record overall which has them right at the top of the West with the best record in the entire NBA. They have been a great road team this season too with their 16-5 road record. Meanwhile, the Bucks haven't looked good in their games this season with their 18-24 record overall which has them in the bottom half of the East. They haven't looked that great on their home court either with their 9-10 home record this year. They are off a win over the Hawks in their last one, but they won that game by 2 points against a shorthanded Hawks team after leading by double digits for a majority of the game. That almost turned into a loss with a big blown lead, and the Bucks haven't even looked that good lately as they are only 5-5 in their last 10 games. The Thunder have been one of the best teams in the NBA all season, even going back to last year as they are the defending champions, and they are starting to get hot again after going through a rough stretch. They are 7-3 in their last 10 games now and they are off a big road win over the Cavaliers in their last one. The Bucks have been a disaster this season and with the way they have looked for most of the year, they don't have the talent to compete with the Thunder. The best way to place a bet here is on the Thunder to cover the spread in this game. 

Thunder Bucks Prediction:  Our NBA Pick for Wednesday, January 21, 2026 (9:30 pm ET start time) is Thunder 121 Bucks 101.

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Oklahoma City Thunder: 20-10 ATS against Central division opponents. 13-6 ATS off a road blowout win by 20 points or more. 18-9 ATS after scoring 136 points or more. 14-5 UNDER off a road blowout win by 20 points or more. 16-10 UNDER after scoring 136 points or more.

Milwaukee Bucks: 33-42 ATS in non-conference games. 20-33 ATS when playing only their 2nd game in 5 days. 4-8 ATS at home versus good defensive teams - allowing 108 points/game or less. 19-6 UNDER against Northwest division opponents. 20-11 UNDER after a win by 6 points or less.

Oklahoma City Thunder:  A. Caruso (SG) Day To Day - Groin. J. Williams (PF) Day To Day - Back. J. Williams (SG) Out - Thigh. I. Hartenstein (C) Day To Day - Calf. N. Topic (PG) Out - Groin. T. Sorber (C) Out For Season - Knee.

Milwaukee Bucks:  T. Prince (SF) Out - Neck.

“The thing that I love about this team is we have a group of guys that see those types of setbacks as a challenge. And that became our challenge tonight with only Chet in the frontcourt. So, we played small [for] a lot of minutes. Kenrich did a great job, but the whole team did a great job. Even with Allen out there, we went small a lot in the first half, and the guys really scrapped and fought.” - Mark Daigneault after his team’s win against the Cavaliers in their game on Monday.

“Just size. We thought putting size in the lineup would be great. And when you do that, you have to separate the guards. And I mean, our second unit was all plus tonight, so I thought it went really well for us. Pete Nance was phenomenal.” - Doc Rivers after his team’s win against the Hawks in their game on Monday.

PG Shai Gilgeous-Alexander

SG Luguentz Dort

SF Alex Caruso

PF Chet Holmgren

C Jaylin Williams

PG Ryan Rollins

SG AJ Green

SF Kyle Kuzma

PF Giannis Antetokounmpo

C Myles Turner

PPG: Shai Gilgeous-Alexander (31.8)

APG: Shai Gilgeous-Alexander (6.2)

Reb/G: Isaiah Hartenstein (10.4)

PPG: Giannis Antetokounmpo (28.5)

APG: Kevin Porter Jr. (7.4)

Reb/G: Giannis Antetokounmpo (9.8)

Coaches:

Oklahoma City Thunder: Mark Daigneault (6th season)

Milwaukee Bucks: Doc Rivers (3rd season)