by Rod Pearson
Monday, Nov 24, 2025
Game Time: 12:00 pm ET, Saturday, November 29, 2025
Venue: Michigan Stadium, Ann Arbor, MI
Where to Watch: FOX
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Ohio State -10.5, Michigan +10.5; Over/Under: 44.5 points
Bet365: Point Spread: Ohio State -10, Michigan +10; Over/Under: 44.5 points
BetMGM: Point Spread: Ohio State -10, Michigan +10; Over/Under: 44.5 points
Season Record
Ohio State Buckeyes: 11-0 (8-0) (2nd place, Big Ten)
Michigan Wolverines: 9-2 (7-1) (4th place, Big Ten)
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Recent Form
Ohio State Buckeyes: won their last game at home against the Rutgers Scarlet Knights 42-9.
Michigan Wolverines: won their last game on the road against the Maryland Terrapins 45-20.
Ohio State Buckeyes vs Michigan Wolverines Preview and Analysis
Ohio State is entering this game with an 11-0 record overall and they have an 8-0 record in their conference games too. They are 7-0 in their home games, 4-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against Rutgers 42-9. Julian Sayin was the starting QB and he completed 13/19 passes for 157 passing yards, 2 touchdowns, and 0 interceptions. Bo Jackson led the team in rushing yards with 110 and 2 TDs. Max Klare led the receivers with 105 receiving yards on 7 receptions and 1 TD. Caden Curry led the defense in that game with 4 solo tackles and 2 assisted tackles while Caden Curry led the defense in sacks with 2. No one on the defense came away with an interception for them in that one.
Michigan is entering this game with a 9-2 record overall and they have a 7-1 record in their conference games too. They are 5-0 in their home games, 4-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against Maryland 45-20. Bryce Underwood was the starting QB and he completed 16/23 passes for 215 passing yards, 2 touchdowns, and 0 interceptions. Bryson Kuzdzal led the team in rushing yards with 100 and 3 TDs. Andrew Marsh led the receivers with 76 receiving yards on 5 receptions and 1 TD. Jaishawn Barham and Brandyn Hillman each led the defense in that game with 3 solo tackles and 1 assisted tackle while Jaishawn Barham, Tré Williams, and Derrick Moore each led the defense in sacks with 1. Mason Curtis came away with the only interception for them in that one.
Ohio State vs Michigan Prediction
The current betting odds have Ohio State listed as a 10.5 point favorite in this game according to Draftkings Sportsbook. Ohio State has looked great in their games this season with their 11-0 record overall and their 8-0 conference record which has them right near the top of the Big Ten. They are currently ranked 1st overall in the nation and are one of the few undefeated teams left. Meanwhile, Michigan has looked really good in their games this season with their 9-2 record overall and their 7-1 conference record which has them right near the top of the Big Ten. They are currently ranked inside the top 25 teams in the nation, but they don't have a playoff spot at the moment. They are off a 45-20 win over Maryland in their last one, playing one of their best games of the season, and now they come into this one with everything on the line. Michigan can still make a case for the CFP with a win over Ohio State, but Ohio State is going to bring their best effort to make sure that doesn't happen. Ohio State really doesn't need this game since they will still make the CFP even if they lose, but this is definitely a game they want to make a statement in. They won the National Championship last season, but they lost this game and haven't beaten Michigan in years either. They are going to be highly focused on finally winning this game and getting over the hump, especially with a chance to keep Michigan out of the CFP too. No team has even played a close game with Ohio State this season and this game is going to be no different. The best way to place a bet here is on Ohio State to cover the spread in this game.
Ohio State Michigan Prediction: Our NCAAF Pick for Saturday, November 29, 2025 (12:00 pm ET start time) is Ohio State 31 Michigan 13.
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NCAAF Betting Trends
Ohio State Buckeyes: 26-12 ATS in all lined games. 7-2 ATS as a favorite of 10.5 to 21 points. 19-8 ATS against conference opponents. 18-7 ATS after a win by 17 or more points. 25-15 UNDER in all lined games. 10-2 UNDER as a road favorite.
Michigan Wolverines: 4-7 ATS in a home game where the total is between 42.5 and 49. 24-36 ATS vs. good passing defenses - allowing 5.75 or less passing yards/att. 10-4 UNDER when playing against a top-level team (Win Pct. > 75%). 9-4 UNDER vs. good offensive teams - scoring 31 or more points/game.
Key Injuries
Ohio State Buckeyes: M. Roy (DL) Questionable - Undisclosed. J. Carter (DL) Questionable - Undisclosed. A. Tounkara (DL) Questionable - Undisclosed. L. George (DL) Questionable - Undisclosed. C. Tate (WR) Questionable - Undisclosed. M. Maggs (QB) Questionable - Undisclosed. Q. Porter (WR) Questionable - Undisclosed. M. Hartford (S) Questionable - Undisclosed. D. Jones (WR) Questionable - Undisclosed. J. Smith (WR) Questionable - Undisclosed.
Michigan Wolverines: S. Morgan (WR) Questionable - Undisclosed. E. Hausmann (LB) Questionable - Undisclosed. J. Haynes (RB) Questionable - Foot. E. Link (OG) Questionable - Undisclosed. R. Moore (CB) Questionable - Undisclosed. H. Hansen (TE) Questionable - Undisclosed. J. Taylor (WR) Questionable - Undisclosed. C. Charleston (WR) Out - Undisclosed. D. Baxter (DL) Out - Undisclosed. J. Hood (LB) Out - Undisclosed. D. Johnson (RB) Out - Undisclosed. I. Stewart (WR) Out - Undisclosed. A. Babalola (OG) Out - Knee.
Notable Quotes
“They're always in the back of our mind in terms of what we’re working toward, we know this is the last game of the year and what it means to everybody here. It was a good look in everyone's eye in the locker room. We just need to focus on what really matters.” - Ryan Day after his team’s win against Rutgers in their last game.
“Proud of this team. How they prepared and how they never looked forward the whole week. It's so easy to be able to do that with that game on the horizon.” - Sherrone Moore after his team’s win against Maryland in their last game.
Starting Lineups
Ohio State Buckeyes
WR Tate, Carnell
WR Smith, Jeremiah
WR Inniss, Brandon
TE Klare, Max
QB Sayin, Julian
RB Jackson, Bo
Michigan Wolverines
WR McCulley, Donaven
WR Goodwin, Channing
WR Morgan, Semaj
TE Klein, Marlin
QB Underwood, Bryce
RB Haynes, Justice
Statistical Leaders
Ohio State Buckeyes
Passing: Julian Sayin (2,832)
Rushing: Bo Jackson (835)
Receiving: Jeremiah Smith (902)
Touchdowns: Jeremiah Smith (11)
Michigan Wolverines
Passing: Bryce Underwood (2,166)
Rushing: Jordan Marshall (871)
Receiving: Andrew Marsh (641)
Touchdowns: Justice Haynes (10)
Coaches:
Ohio State Buckeyes: Ryan Day (8th season)
Michigan Wolverines: Sherrone Moore (2nd season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
