Notre Dame Fighting Irish vs Clemson Tigers Prediction, Picks and Game Preview - 02/26/2025

Game Time: 7:00 pm ET, Wednesday, February 26, 2025

Venue:  Littlejohn Coliseum, Clemson, SC

Where to Watch:  ACC Network

DraftKings:  Point Spread:  Notre Dame +13.5, Clemson -13.5; Over/Under:  136.5 points

Bet365:  Point Spread:  Notre Dame +13.5, Clemson -13.5; Over/Under:  136.5 points

BetMGM:  Point Spread:  Notre Dame +13.5, Clemson -13.5; Over/Under:  136.5 points

Notre Dame Fighting Irish:  12-15 (6-10) (13th place, ACC)

Clemson Tigers:  22-5 (14-2) (2nd place, ACC)

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Notre Dame Fighting Irish:  2-3  last 5

Clemson Tigers:  4-1  last 5

Notre Dame is entering this game with a 12-15 record overall, a 6-10 record in conference games, and they are 3-7 in their road games this season where they will be in this game. They are coming off a win against the Pittsburgh Panthers in their last game. Tae Davis led the team in points per game in that game with 21 while Markus Burton was next on the team with 20. Markus Burton, Sir Mohammed, and Julian Roper II each led the team in assists with 3 in that game while Kebba Njie led the team in rebounds with 7. They were 56.3% from the field, 35.3% from 3-point range, and 80% from the free throw line with their shooting in that game. Their offense is averaging 73.3 PPG and their defense is allowing their opponents to average 71.9 PPG against them. Notre Dame has an ATS record of 11-15-1 this season and their O/U record is 13-13-1.

Clemson is entering this game with a 22-5 record overall, a 14-2 conference record, and they are 13-2 in their home games this season where they will be in this game. They are coming off a win against the SMU Mustangs in their last game. Jaeden Zackery led the team in points in that game with 19 while Chase Hunter was next on the team with 17. Jaeden Zackery and Dillon Hunter each led the team in assists with 7 in that game while Viktor Lakhin and Jaeden Zackery each led the team in rebounds with 6. They were 49.1% from the field, 48.3% from 3-point range, and 81.8% from the free throw line with their shooting in that game. Their offense is averaging 77.5 PPG and their defense is allowing their opponents to average 66.5 PPG against them. Clemson has an ATS record of 17-10 this season and their O/U record is 14-13.

The current betting odds have Clemson listed as a 13.5 point favorite in this game according to Draftkings Sportsbook. Clemson has looked really good in their games this season with their 22-5 record overall and their 14-2 conference record which has them right near the top of the ACC. They have also looked great on their home court with their 13-2 home record this season. Meanwhile, Notre Dame has looked terrible in their games this season with their 12-15 record overall and their 6-10 conference record which has them right near the bottom of the ACC. They have also been a terrible road team with their 3-7 road record this year. They are coming off a win over Pittsburgh in their last one, but they are still 2-3 in their last 5 games and haven't looked good lately with some bad losses under their belt. Their last 2 losses were both by double digits, and now they are facing one of the best teams in the conference who have been rolling lately. Clemson is coming off a big road win over SMU in their last one and they have a ton of momentum on their side with 4 wins in a row now. They also have the only conference win over Duke this season and have been emerging as a real tournament threat. They took their loss to Georgia Tech but bounced back with a win over Duke and their last 3 games since beating Duke have all been wins by double digits. Clemson is rolling right now and a team like Notre Dame is not going to stop them with the way they have been getting crushed by better ACC teams this year. The best way to place a bet here is on Clemson to cover the spread in this game. 

Notre Dame Clemson Prediction:  Our NCAAB Pick for Wednesday, February 26, 2025 (7:00 pm ET start time) is Clemson 74 Notre Dame 56.

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Notre Dame Fighting Irish: 4-11 ATS off a win against a conference rival. 16-30 ATS after playing a home game. 10-24 ATS after 1 or more consecutive wins. 31-18 UNDER as an underdog. 8-2 UNDER off a home win against a conference rival. 18-9 UNDER versus very good teams - outscoring their opponents by 8+ points/game.

Clemson Tigers: 20-12 ATS after playing a road game. 6-3 ATS when playing against a marginal losing team (Win Pct. 40% to 49%). 16-8 ATS versus poor foul drawing teams - attempting 18 free throws/game or less. 6-3 UNDER when playing against a marginal losing team (Win Pct. 40% to 49%). 11-6 1H UNDER off a road win. 

Notre Dame Fighting Irish:  M. Allocco (G) Questionable - Wrist. B. Shrewsberry (G) Questionable - Abdominal.

Clemson Tigers:  C. Reeves (C) Questionable - Ankle. A. Thomas (F) Questionable - Illness. A. Buckner (G) Out - Upper Body.

“Just proud of our guys for fighting, scratching, clawing, kind of doing whatever was needed. They made a commitment to each other on Thursday of, like, man. They were disappointed. They just said, ‘We want to do whatever it takes, whatever possible, to stay together, to scratch, claw and get the job done.” - Micah Shrewsberry after his team’s win against Pitt in their last game. 

"I think so. I hope so. It's hard because tournament play is one-and-done and there's so many things that can go into that: foul trouble, guys not shooting well. But I do think that we have an older group that can deal with some adversity; that has battled a lot of different things; that has shown good poise and maturity with all the different things we've had to deal with, with different styles of play. That's helpful, as well." - Brad Brownell on his team’s experience from the NCAA Tournament last season.

M. Allocco 

M. Burton 

T. Davis 

K. Njie 

B. Shrewsberry

C. Hunter 

V. Lakhin 

I. Schieffelin 

C. Wiggins 

J. Zackery

PPG: M. Burton (20.3)

APG: M. Burton (3)

Reb/G: K. Njie (6.2)

PPG: C. Hunter (17.1)

APG: J. Zackery (3.4)

Reb/G: I. Schieffelin (9.4)

Coaches:

Notre Dame Fighting Irish: Micah Shrewsberry (2nd season)

Clemson Tigers: Brad Brownell (15th season)