Notre Dame Fighting Irish vs Boston College Eagles Prediction, Picks and Game Preview - 11/01/2025

by Rod Pearson

Wednesday, Oct 29, 2025
Game Time: 3:30 pm ET, Saturday, November 1, 2025
Venue:  Alumni Stadium, Chestnut Hill, MA
Where to Watch:  ESPN


Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  Notre Dame -28.5, Boston College +28.5; Over/Under:  56.5 points
Bet365:  Point Spread:  Notre Dame -29, Boston College +29; Over/Under:  56.5 points
BetMGM:  Point Spread:  Notre Dame -28.5, Boston College +28.5; Over/Under:  56.5 points

Season Record

Notre Dame Fighting Irish:  5-2 (0-0) (FBS Independent)
Boston College Eagles:  1-7 (0-5) (17th place, ACC)

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Recent Form
Notre Dame Fighting Irish:  won their last game at home against the USC Trojans 34-24.
Boston College Eagles:  lost their last game on the road against the Louisville Cardinals 38-24.


Notre Dame Fighting Irish vs Boston College Eagles Preview and Analysis


Notre Dame is entering this game with a 5-2 record overall and they have a 0-0 record in their conference games too. They are 4-1 in their home games, 1-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against USC 34-24. CJ Carr was the starting QB and he completed 16/26 passes for 136 passing yards, 1 touchdown, and 1 interception. Jeremiyah Love led the team in rushing yards with 228 and 1 TD. Jordan Faison led the receivers with 60 receiving yards on 6 receptions. Adon Shuler led the defense in that game with 7 solo tackles and 3 assisted tackles while Boubacar Traore and Kyngstonn Viliamu-Asa each led the defense in sacks with 1. Christian Gray and Luke Talich came away with 1 interception for them in that one.
 
 
 
Boston College is entering this game with a 1-7 record overall and they have a 0-5 record in their conference games too. They are 1-3 in their home games, 0-4 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against Louisville 38-24. Grayson James was the starting QB and he completed 23/46 passes for 244 passing yards, 3 touchdowns, and 2 interceptions. Jordan McDonald led the team in rushing yards with 80. Kaelan Chudzinski led the receivers with 80 receiving yards on 4 receptions and 1 TD. TJ Green led the defense in that game with 6 solo tackles and 2 assisted tackles while TJ Green led the defense in sacks with 1. KP Price came away with the only interception for them in that one.


Notre Dame vs Boston College Prediction

The current betting odds have Notre Dame listed as a 28.5 point favorite in this game according to Draftkings Sportsbook. Notre Dame has looked good in their games this season with their 5-2 record overall which has them ranked inside the top 25. They are off a 34-24 win over USC in their last one and they have looked better and better as the season has gone on. They started the year 0-2 with losses to Miami and Texas A&M, but those 2 losses have aged nicely. Both of those losses were also in tight games by 3 points or less, and now they have been starting to roll over their opponents lately. They are starting to look like one of the better teams in the nation now, and they are also coming out of their bye week so they have had extra time to prepare for this one. Meanwhile, Boston College has looked terrible in their games this season with their 1-7 record overall and their 0-5 conference record which has them right at the bottom of the ACC. They started the season with some fight and were playing in tighter games, but lately they have been getting blown out in a lot of their losses. They are off a 38-24 loss to Louisville in their last one and their defense hasn't looked that good all season, giving up a ton of points in their games. This Notre Dame offense has been starting to roll lately, and the defense has looked a lot better from where they started the season too. The best way to place a bet here is on Notre Dame to cover the spread in this game.

Notre Dame Boston College Prediction:  Our NCAAF Pick for Saturday, November 1, 2025 (3:30 pm ET start time) is Notre Dame 56 Boston College 13.
Don't miss our champion handicappers free picks and expert football picks today. And if you enjoyed this Notre Dame Fighting Irish Boston College Eagles prediction, be sure to drop by every day for our weekly NCAAF predictions and previews.

NCAAF Betting Trends


Notre Dame Fighting Irish: 8-3 ATS against ACC opponents. 21-9 ATS as a favorite. 12-2 ATS after playing a game at home. 5-0 ATS when playing against a team with a losing record. 22-14 OVER in all lined games. 7-2 OVER as a road favorite. 5-0 OVER when playing against a team with a losing record.

Boston College Eagles: 4-9 ATS off a loss against a conference rival. 4-8 ATS after playing their last game on the road. 2-5 ATS vesus good rushing teams - averaging 4.75 rushing yards/carry or more. 20-12 OVER in all lined games. 12-5 OVER in home lined games. 8-4 OVER after playing their last game on the road.

Key Injuries


Notre Dame Fighting Irish:  B. Schrauth (OG) Out - Knee. L. Thomas (DL) Questionable - Concussion. G. Rubio (DL) Questionable - Elbow. P. Jones (OG) Questionable - Ankle. C. Jagusah (OG) Questionable - Arm. M. Gilbert (WR) Questionable - Hand. A. Craig (OG) Out - Knee. W. Black (OG) Questionable - Undisclosed. D. Smith (CB) Questionable - Calf. J. Greathouse (WR) Questionable - Thigh. K. Young (RB) Out - Knee. B. Logan (S) Out - Shoulder. D. Devezin (RB) Out - Shoulder.

Boston College Eagles:  M. Townsend (CB) Questionable - Undisclosed. S. Torrence (CB) Questionable - Undisclosed. O. Stoudmire (DL) Questionable - Undisclosed. J. Skeete (WR) Questionable - Undisclosed. S. Sanders (DL) Questionable - Undisclosed. O. Nwosisi (DL) Questionable - Undisclosed. J. Montague Jr. (WR) Out - Knee. C. Martinez (CB) Questionable - Undisclosed. A. Jackson (CB) Questionable - Leg. J. Hewlett Jr. (LB) Questionable - Undisclosed. W. Graves III (WR) Questionable - Undisclosed. P. Faoa (LB) Questionable - Undisclosed. D. Edgehille (TE) Questionable - Undisclosed. B. Dopson (WR) Questionable - Undisclosed. E. Daugherty (OG) Questionable - Undisclosed. D. Crouch (LB) Questionable - Undisclosed. T. Clemons (DL) Questionable - Undisclosed. J. Blackwell (LB) Questionable - Undisclosed. M. Amedee (DL) Questionable - Undisclosed. T. Richard (RB) Questionable - Undisclosed.

Notable Quotes


"It's not very common in college, not very common in life, to see two guys that are so talented, that deserve the ball in their hands every snap, put the team above themselves, and then make the most of their opportunities. They're not pouting. They're each other's biggest supporter. That might be one of the hardest things we ask our players to do -- put team before me. Everything outside of here says, 'No, you come before team.'" - Marcus Freeman on Price and Love this season.


“I don’t think I’ve ever been in a game where I’ve seen that many long runs.” - Bill O’Brien after his team’s loss against Louisville in their last game. 


Starting Lineups


Notre Dame Fighting Irish
WR Fields, Malachi
WR Faison, Jordan
WR Greathouse, Jaden
TE Raridon, Eli
QB Carr, CJ
RB Love, Jeremiyah

Boston College Eagles
WR Harris, Reed
WR Pough, Dawson
WR Bond, Lewis
TE Franklin, Jeremiah
QB Lonergan, Dylan
RB Richard, Turbo

Statistical Leaders


Notre Dame Fighting Irish
Passing: CJ Carr (1,758)
Rushing: Jeremiyah Love (758)
Receiving: Jordan Faison (436)
Touchdowns: Jeremiyah Love (12)

Boston College Eagles
Passing: Dylan Lonergan (1,394)
Rushing: Turbo Richard (431)
Receiving: Lewis Bond (547)
Touchdowns: Turbo Richard (7)

Coaches:
Notre Dame Fighting Irish: Marcus Freeman (5th season)
Boston College Eagles: Bill O'Brien (2nd season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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