North Texas Mean Green vs Indiana Hoosiers Prediction, Picks and Game Preview - 09/05/2026

Game Time: 12:00 pm ET, Saturday, September 5, 2026

Venue:  Memorial Stadium, Bloomington, IN

Where to Watch:  FOX

DraftKings:  Point Spread:  UNT +40.5, Indiana -40.5; Over/Under:  55.5 points

Bet365:  Point Spread:  UNT +40.5, Indiana -40.5; Over/Under:  55.5 points

BetMGM:  Point Spread:  UNT +40.5, Indiana -40.5; Over/Under:  55.5 points

North Texas Mean Green:  0-0 (0-0) (American)

Indiana Hoosiers:  0-0 (0-0) (Big Ten)

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North Texas Mean Green:  N/A

Indiana Hoosiers:  N/A

North Texas finished last season with a 12-2 record overall and they had a 7-1 record in their conference games too.  They were 6-1 in their home games, 5-1 in their road games, and they were also 1-0 in their neutral site games last season, but they will be on the road for this season opener. Last season, their offense was averaging 45.1 points scored per game while their defense was allowing an average of 26.5 points per game. Their offense also averaged 512.4 yards per game while their defense was allowing an average of 381.9 yards per game. Drew Mestemaker led the team in passing yards with 4,379, Caleb Hawkins led the team in rushing yards with 1,434, and Wyatt Young led the team in receiving yards with 1,264.

 

 

 

Indiana finished last season with a 16-0 record overall and they had a 9-0 record in their conference games too.  They were 7-0 in their home games, 5-0 in their road games, and they were also 4-0 in their neutral site games last season, but they will be at home for this season opener. Last season, their offense was averaging 41.6 points scored per game while their defense was allowing an average of 11.7 points per game. Their offense also averaged 452 yards per game while their defense was allowing an average of 266 yards per game. Fernando Mendoza led the team in passing yards with 3,535, Roman Hemby led the team in rushing yards with 1,120, and Omar Cooper Jr. led the team in receiving yards with 937.

The current betting odds have Indiana listed as a 40.5 point favorite in this game according to Draftkings Sportsbook. Indiana is coming off a great season as the best team in the nation. They won the National Championship and were the 1st team in this new era to go undefeated as National Champions, finishing an impressive 16-0. Curt Cignetti has transformed this team since getting to Indiana and he isn't going to slow down this season at all. They have lost a lot of their talent from last year, including their starting QB, but that has never been an issue for Cignetti. They still brought in tons of talent too and they are already entering the season with a chip on their shoulder, being ranked outside the top 5 despite having not lost a game in over a year. Meanwhile, North Texas is coming off a great season going 12-2 and they were right at the top of their conference last season. They didn't end up with a bid to the CFP though, losing 34-21 to Tulane in the American Championship. Now they are going through some big changes this season too. They lost their starting QB along with the head coach who led them to such a great year. Neal Brown will be taking over the program now, but he had a lot of trouble for years at West Virginia and it is going to be really tough for them to recreate the season they just had after losing so much. They are going to take a step back this season from where they were and Indiana isn't really the kind of team to go easy on their opponents. Indiana was blowing out every team they faced last season and this game will be no different after the way they were ranked to start the year. The best way to place a bet here is on Indiana to cover the spread in this game. 

North Texas Indiana Prediction:  Our NCAAF Pick for Saturday, September 5, 2026 (12:00 pm ET start time) is Indiana 63 North Texas 10.

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North Texas Mean Green: 23-32 ATS in the first two weeks of the season. 18-7 OVER against FBS division opponents. 10-2 OVER in road lined games. 4-0 OVER when the total is between 49.5 and 56.

Indiana Hoosiers: 19-10 ATS in all lined games. 17-8 ATS as a favorite. 12-6 ATS when the total is between 49.5 and 56. 10-5 OVER as a home favorite. 12-6 OVER when the total is between 49.5 and 56.

North Texas Mean Green:  None.

Indiana Hoosiers:  None.

“That’s the biggest threat to us. I think we’ll be talented enough, but can we mesh where we are not just playing for ourselves but each other? That’s the challenge.” - Neal Brown on his team coming into this new college football season. 

“Practice 14 tonight, we’ll walk through scrimmage tomorrow. Then we’ll transition sort of to install things that haven’t been installed yet. Special situations in game week next week. Kellan Wyatt and Stephen Daley can practice right now, are ineligible to play. So we’re taking that day by day. Obviously, we’d love to see that happen. And I think in their case, you’re creating opportunities. You look at Kellan Wyatt, started less than half the games last year and got hurt. And Stephen Daley stepped in, started six out of 16 games and got hurt. Both had pro potential, but because of injury, didn’t end up in NFL camps. So we’d have to make no roster cuts if they’re eligible to play.” - Curt Cignetti on his team coming into this new CFB season.

WR Tipton, Baron

WR Milliner, Corri

WR Tyre, James

TE Reese, Max

QB Jackson, Tayven

RB White, Jahiem

WR Marsh, Nick

WR Becker, Charlie

WR Morris, Tyler

TE Schott, Brock

QB Hoover, Josh

RB Richard, Turbo

Passing: N/A

Rushing: N/A

Receiving: N/A

Touchdowns: N/A

Passing: N/A

Rushing: N/A

Receiving: N/A

Touchdowns: N/A

Coaches:

North Texas Mean Green: Neal Brown (1st season)

Indiana Hoosiers: Curt Cignetti (3rd season)