New York Yankees Vs Cleveland Guardians Game Prediction, Odds and Preview - 10/16/2022

by James Q

Saturday, Oct 15, 2022

New York Yankees Vs Cleveland Guardians Game Prediction, Odds and Preview - 10/16/2022 

Game Time: 7:37 pm ET, Sunday, October 16th, 2022
Venue: Progressive Field, Cleveland, Ohio
Where to Watch: TBS, MLBN

Opening MLB Odds at USA Sportsbooks

DraftKings: Moneyline:  (will update)
BetMGM:  Moneyline:  
PointsBet:  Moneyline: 

Season Record

Guardians: 92-70, 1st place AL Central. / 1-1 ALDS
Yankees: 99-63, 1st place Al East. / 1-1 ALDS

Game 4 of the ALDS.  We are guaranteed to get Game 4 since the Cleveland Guardians won Game 2, 4-2.  There will be no sweep in this series.  The Yankees (like the Dodgers in the West) lost home field advantage by splitting the first two games in Yankee Stadium.  We are tied at 1-1.  Game 3 will go off (today) Saturday.  Game 4 could be for all the marbles for either team,  or it could be another game that notches the series and sends everyone back to the Bronx for a decisive game 5.  So, we have to find the best betting opportunity.

The New York Yankeeshad everything about the ALDS in the palm of their hand… They won Game 1 and took a 2-0 lead in the first inning of game 2 off a Giancarlo Stanton 2 run home run.  It was going to be smooth sailing… and then they did not score for the next 9 innings.  For the league’s #2 team in scoring this has been a familiar refrain.  Big game after big game in win after win… and then inexplicably the pump goes dry.  Yankee manager Aaron Boone has not found a reliable way of shaking things up when the pump does go dry.  If they have trouble scoring in Cleveland?... Like they did in all of August?... The series may not return to the Bronx. Followed by Aaron Boone may not return to the bench… followed by Aaron Judge May not get that 10 year contract with more zeroes than you can imagine (from the Yankees).

The Cleveland Guardians get two games on their home field against a great Yankee team that badly swooned at the end of the season. These games are their best chance to pounce and take the series.  In Game 2 Cleveland had 9 hits that produced 4 runs and needed an extra inning to get the job done.  They scored 2 runs in the top of the tenth inning… and held on to win it.  “We just try to find a way on base anyway we have,” Naylor said. “If it’s a bloop hit, it’s a bloop hit. If it’s a hard-hit single, double — whatever the case it — we just try to hustle. Try to make things happen on the field, try to put pressure on the defense.” Guardians manager Terry Francona is encouraged by the way his team held the Yankees scoreless over the last 9 innings of a 10 inning game.  He relies on his pitching and they rarely let him down lately.

Kyle Hunter  is 35-2 in MLB picks over the last 30 days for a profit of +$21,500!! You should be following along with the expert handicappers at Get Kyle Hunter’s picks… It's available right now at the Shop Picks page, where you can find all of the Best Bets from our champion sports handicappers. You can also get help with all your favorite sports and sport betting.., MLB, NBA, NCAAF, NFL, NHL.  Follow a handicapper all year long to ensure a profitable year from your sports betting.

New York Yankees vs Cleveland Guardians Review and Analysis

Recent Form

NYY: 100-64, 286 ML, 77-83-4 O/U, 42-39 on the road.
CLE: 95-71, 2441 ML, 78-82-6 O/U, 48-35 at home *.

Offensive Analysis

The Yankees finished the season 2nd in runs scored with 4.98 per game, 15th in batting average with .241, and 5th in OBP with .325.  

Cleveland finished the season 16th in runs scored per game with 4.31, 7th in batting average with .254, and 12th in OBP with .316.

Defensive Analysis

The Yankees Pitchers finished the season 3rd in ERA with 3.30, 3rd in WHIP with 1.12, and their fielders are 7th in errors with 79 on the season.

Cleveland’s pitchers finished the season 6th in ERA with 3.47, 5th in WHIP with 1.16, and the fielders are 5th in errors with only 75 on the season.

New York Yankees vs Cleveland Guardians Prediction

Our prediction for Sunday, October 16th is… Guardians 5 - Yankees 3

Bet on the Guardians on the moneyline.

The second game in Cleveland (series Game 4 ) could see the Yankees up by one or the Guardians up by one depending on what happens tonight in Game 3… Either way the best return on your bet will be the Guardians to win…  since Millions of dollars were flushed out of Gambler’s bankrolls betting on the Yankees in August.  It would seem the better return may also be the better bet. 

Don't miss our champion handicappers' Free MLB Picks and Premium Selections every day here at Just click on Shop Picks for our Best Bets, or click on Shop Subscriptions to join for a week or a month. And if you enjoyed this Yankees/Guardians preview, be sure to bookmark for our daily Game Previews and Predictions. 

MLB Betting Trends

The Guardians are 209-180 in all games the last 3 seasons (+21.7 UNITS).
The Guardians are 18-9 on the road when the total is 7 or less the last 3 seasons.
The Yankees are 17-5 this season at home when the money line is -100 to -150.

Players to Watch

TBD (will update)

Starting Lineups

Yankees: 2B DJ LaMahieu, 1B Anthony Rizzo, LF Oswaldo Cabrera, 3B Josh Donaldson, SS Oswald Peraze, DH Aaron Judge, RF Marwin Gonzalez, C Kyle Higashioka, CF Aaron Hicks

Guardians: LF Steven Kwan, SS Amed Rosario, 3B Jose Ramirez, RF Oscar Gonzalez, 1B Josh Naylor, DH Owen Miller, 2B Andres Giminez, C Austin Hedges, CF Myles Straw


Yankees: Aaron “I am history” Boone
Guardians: Terry “Let’s make history” Francona

Weather Forecast 

Partly Cloudy, 20 MPH winds, Humidity 51%... Most of the country is descending into gross weather.  Totally bolstering my call for every major American sport to have a dome to pay in.

James Q

About the Author:

James Q. has been involved with sports and gambling his entire life. A former division 1 scholarship basketball player, James understands sports (and especially basketball) inside-and-out. Following his basketball playing days, James parlayed his gambling skills into a semi-pro poker career. James resides in Los Angeles, and especially loves the Los Angeles Clippers, Los Angeles Rams, and Los Angeles Dodgers. And when he isn't betting on sports (and writing about it), James can be found performing stand-up comedy on the Sunset Strip.

All photographic images used for editorial content have been licensed from the Associated Press.

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