by Rod Pearson
Friday, Nov 28, 2025
Game Time: 8:15 pm ET, Monday, December 1, 2025
Venue: Gillette Stadium, Foxborough, MA
Where to Watch: ESPN
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Giants +7.5, Patriots -7.5; Over/Under: 46.5 points
Bet365: Point Spread: Giants +7, Patriots -7; Over/Under: 46.5 points
BetMGM: Point Spread: Giants +7.5, Patriots -7.5; Over/Under: 46.5 points
Season Record
New York Giants: 2-10 (4th place, NFC East)
New England Patriots: 10-2 (1st place, AFC East)
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New York Giants: lost their last game on the road against the Detroit Lions 34-27 in overtime.
New England Patriots: won their last game on the road against the Cincinnati Bengals 26-20.
New York Giants vs New England Patriots Preview and Analysis
The Giants are entering this game with a 2-10 record overall and they have a 1-3 record in their divisional games too. They are 2-3 in their home games, 0-7 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the Detroit Lions 34-27 in OT. Jameis Winston was the starting QB and he completed 18/36 passes for 366 passing yards, 2 touchdowns, and 1 interception. Tyrone Tracy Jr. led the team in rushing yards with 62. Wan'Dale Robinson led the receivers with 156 receiving yards on 9 receptions and 1 TD. Bobby Okereke led the defense in that game with 6 solo tackles and 2 assisted tackles while Darius Alexander led the defense in sacks with 2. Jevon Holland came away with the only interception for them in that one.
The Patriots are entering this game with a 10-2 record overall and they have a 3-0 record in their divisional games too. They are 4-2 in their home games, 6-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Cincinnati Bengals 26-20. Drake Maye was the starting QB and he completed 22/35 passes for 294 passing yards, 1 touchdown, and 1 interception. TreVeyon Henderson led the team in rushing yards with 66. Hunter Henry led the receivers with 115 receiving yards on 7 receptions and 1 TD. Carlton Davis III led the defense in that game with 4 solo tackles and 4 assisted tackles while Harold Landry III led the defense in sacks with 1. Marcus Jones came away with the only interception for them in that one.
Giants vs Patriots Prediction
The current betting odds have the Patriots listed as a 7.5 point favorite in this game according to Draftkings Sportsbook. The Patriots have looked great in their games this season with their 10-2 record overall which has them right at the top of the AFC East with the best record in the entire NFL. They have looked good on their home field too with their 4-2 home record. Meanwhile, the Giants have looked terrible in their games this season with their 2-10 record overall which has them right at the bottom of the NFC East with one of the worst records in the entire NFL. They have been dealing with a ton of injuries to key players this season and that has hurt their team a lot. They have already been eliminated from playoff contention and even though they haven't looked that bad lately, they still find ways to lose games. Their defense has looked terrible this year with multiple blown leads and they are off a 34-27 loss to the Lions last week in a game they were always leading. Dart should be back, but he doesn't have any talent to work with on offense at the moment. The Patriots are off a 26-20 win over the Bengals in their last one and it wasn't a pretty win, but they have been finding ways to win games all season. They have taken a big step this year with their new head coach, and they have been rolling over a lot of teams. Drake Maye has looked great in this offense so they are going to put up points on one of the worst defenses in the league here, and the Patriots defense has looked a lot better lately. The best way to place a bet here is on the Patriots to cover the spread in this game.
Giants Patriots Prediction: Our NFL Pick for Monday, December 1, 2025 (8:15 pm ET start time) is Patriots 24 Giants 14.
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NFL Betting Trends
New York Giants: 23-12 ATS against AFC East division opponents. 22-15 ATS on the road off a road loss. 22-14 ATS on the road versus good rushing defenses - allowing 90 rushing yards/game or less. 14-7 UNDER in all games where the total is between 42.5 and 49 points. 9-4 UNDER in non-conference games.
New England Patriots: 0-4 ATS against NFC East division opponents. 6-13 ATS in home games. 1-6 ATS in a home game where the total is between 42.5 and 49 points. 9-4 UNDER as a favorite.
Key Injuries
New York Giants: D. Flannigan-Fowles (LB) Injured - Neck. D. Slayton (WR) Injured - Hamstring. D. Davidson (DL) Injured - Knee. D. Lawrence II (DL) Injured - Elbow. P. Adebo (CB) Injured - Knee. D. Banks (CB) Injured - Hip. W. Robinson (WR) Injured - Ankle. K. Thibodeaux (LB) Injured - Shoulder. T. Nubin (S) Injured - Neck. K. Black (CB) Injured - Bicep. J. Dart (QB) Injured - Concussion.
New England Patriots: H. Henry (TE) Injured - Toe. M. Moses (OT) Injured - Illness. H. Landry III (LB) Injured - Knee. K. Tonga (DL) Injured - Chest. J. Tavai (LB) Injured - NIR - Personal. K. Chaisson (LB) Injured - Ankle. B. Schooler (S) Injured - Ankle. C. Barmore (DL) Injured - NIR - Other. C. Dippre (TE) Injured - Back. J. Wilson (C) Injured - Ankle.
Notable Quotes
“We’re trying to win the game, so we want to score as many points as possible. We thought that was a place to be aggressive.” - Mike Kafka after his team’s loss against the Lions in their last game.
“That’s what happens in this league. You need everybody. You go through the season and you go on the road and it’s tough. Nobody wants to talk about numbers and records, that doesn’t mean (expletive).” - Mike Vrabel after his team’s win against the Bengals in their last game.
Starting Lineups
New York Giants
WR Hodgins, Isaiah
WR Slayton, Darius
WR Robinson, Wan'Dale
TE Johnson, Theo
QB Dart, Jaxson
RB Tracy Jr., Tyrone
New England Patriots
WR Boutte, Kayshon
WR Hollins, Mack
WR Diggs, Stefon
TE Henry, Hunter
QB Maye, Drake
RB Henderson, TreVeyon
FB Westover, Jack
Statistical Leaders
New York Giants
Passing: Jaxson Dart (1,417)
Rushing: Cam Skattebo (410)
Receiving: Wan'Dale Robinson (794)
Touchdowns: Cam Skattebo (7)
New England Patriots
Passing: Drake Maye (3,130)
Rushing: TreVeyon Henderson (558)
Receiving: Stefon Diggs (679)
Touchdowns: TreVeyon Henderson (6)
Coaches:
New York Giants: Mike Kafka (Interim)
New England Patriots: Mike Vrabel (1st season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
