New Orleans Saints vs Tennessee Titans Prediction, Preview and Odds - 12/28/2025

Game Time: 1:00 pm ET, Sunday, December 28, 2025

Venue:  Nissan Stadium, Nashville, TN

Where to Watch:  CBS

DraftKings:  Point Spread:  Saints -2.5, Titans +2.5; Over/Under:  39.5 points

Bet365:  Point Spread:  Saints -2.5, Titans +2.5; Over/Under:  39.5 points

BetMGM:  Point Spread:  Saints -2.5, Titans +2.5; Over/Under:  39.5 points

New Orleans Saints:  5-10 (4th place, NFC South)

Tennessee Titans:  3-12 (4th place, AFC South)

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New Orleans Saints:  won their last game at home against the New York Jets 29-6.

Tennessee Titans:  won their last game at home against the Kansas City Chiefs 26-9.

The Saints are entering this game with a 5-10 record overall and they have a 3-2 record in their divisional games too. They are 3-5 in their home games, 2-5 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the New York Jets 29-6. Tyler Shough was the starting QB and he completed 32/49 passes for 308 passing yards, 1 touchdown, and 0 interceptions. Taysom Hill led the team in rushing yards with 42. Chris Olave led the receivers with 148 receiving yards on 10 receptions and 2 TDs. Alontae Taylor led the defense in that game with 5 solo tackles and 2 assisted tackles while Cameron Jordan led the defense in sacks with 2. Jonas Sanker came away with the only interception for them in that one.

 

 

 

The Titans are entering this game with a 3-12 record overall and they have a 0-5 record in their divisional games too. They are 1-7 in their home games, 2-5 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Kansas City Chiefs 26-9. Cameron Ward was the starting QB and he completed 21/28 passes for 228 passing yards, 2 touchdowns, and 0 interceptions. Tony Pollard led the team in rushing yards with 102. Elic Ayomanor led the receivers with 58 receiving yards on 7 receptions. James Williams led the defense in that game with 8 solo tackles and 1 assisted tackle while Truman Jones led the defense in sacks with 1.5. No one on the defense came away with an interception for them in that one.

The current betting odds have the Saints listed as a 2.5 point favorite in this game according to Draftkings Sportsbook. The Saints haven't looked good in their games this season with their 5-10 record overall which has them right at the bottom of the NFC South. They haven't been a great road team either with their 2-5 road record this year. Meanwhile, the Titans have looked terrible in their games this season with their 3-12 record overall which has them right at the bottom of the AFC South with one of the worst records in the entire NFL. They have looked terrible on their home field too with their 1-7 home record this season. The Titans have been one of the worst teams in the NFL all season with a really up and down offense that has been banged up for a lot of the season. They have looked a lot better lately with 2 of their wins coming in their last 3 games, but they still lack a lot of talent and have one of the worst rosters in the NFL. They are off a 26-9 win over the Chiefs in their last one, but the Chiefs have basically given up on the season with all of their injuries now. The Saints are off a 29-6 win over the Jets in their last one and they have looked a lot better lately. They looked like one of the worst teams in the NFL to start the season, but they have looked a lot better on offense since making the switch to Tyler Shough at QB. They have some momentum on their side now with 3 wins in a row, and their defense has also looked better lately too. The Saints also have a lot more talent than the Titans have on both sides of the ball so the Saints definitely have the edge here with how much better they have looked lately. The best way to place a bet here is on the Saints to cover the spread in this game. 

Saints Titans Prediction:  Our NFL Pick for Sunday, December 28, 2025 (1:00 pm ET start time) is Saints 27 Titans 20.

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New Orleans Saints: 4-1 ATS vs. poor passing teams averaging 175 or less passing yards/game. 6-3 ATS vs. poor teams - outscored by 6+ points per game on the season. 5-2 ATS vs. poor offensive teams - scoring 17 or less points/game. 19-8 UNDER in all games where the total is between 35.5 and 42 points. 12-3 UNDER vs. bad defensive teams who give up 24 or more points/game. 

Tennessee Titans: 16-32 ATS in all games. 15-25 ATS as an underdog. 0-8 ATS off an upset win as an underdog. 6-14 ATS after playing a game at home. 11-6 UNDER in games where the line is +3 to -3. 11-4 UNDER when playing against a team with a losing record.

New Orleans Saints:  None.

Tennessee Titans:  None.

“We're super proud of what we're putting together. The season hasn't gone exactly as we wanted it to, but we kind of stayed resilient through that.” - Tyler Shough after their win against the Jets in their last game. 

“What a great team win. That’s the way it’s supposed to be. It’s been a long time coming since we’ve won a home game here.” - Mike McCoy after his team’s win against the Chiefs in their last game. 

WR Tipton, Mason

WR Austin Jr., Kevin

WR Olave, Chris

TE Johnson, Juwan

QB Shough, Tyler 

RB Estimé, Audric

WR Ayomanor, Elic

WR Jefferson, Van

WR Dike, Chimere

TE Okonkwo, Chig

QB Ward, Cam

RB Pollard, Tony

Passing: Tyler Shough (1,792)

Rushing: Alvin Kamara (471)

Receiving: Chris Olave (1,044)

Touchdowns: Chris Olave (8)

Passing: Cam Ward (2,866)

Rushing: Tony Pollard (949)

Receiving: Chig Okonkwo (503)

Touchdowns: Tony Pollard (5)

Coaches:

New Orleans Saints: Kellen Moore (1st season)

Tennessee Titans: Mike McCoy (Interim)