Game Time: 4:05 pm ET, Sunday, November 2, 2025
Venue: SoFi Stadium, Inglewood, CA
Where to Watch: FOX
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Saints +14, Rams -14; Over/Under: 43.5 points
Bet365: Point Spread: Saints +14, Rams -14; Over/Under: 44 points
BetMGM: Point Spread: Saints +14, Rams -14; Over/Under: 44 points
Season Record
New Orleans Saints: 1-7 (4th place, NFC South)
Los Angeles Rams: 5-2 (2nd place, NFC West)
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New Orleans Saints: lost their last game at home against the Tampa Bay Buccaneers 23-3.
Los Angeles Rams: won their last game at a neutral site against the Jacksonville Jaguars 35-7.
New Orleans Saints vs Los Angeles Rams Preview and Analysis
The Saints are entering this game with a 1-7 record overall and they have a 0-1 record in their divisional games too. They are 1-4 in their home games, 0-3 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the Tampa Bay Buccaneers 23-3. Spencer Rattler was the starting QB and he completed 15/21 passes for 136 passing yards, 0 touchdowns, and 1 interception before getting replaced by Tyler Shough who completed 17/30 passes for 128 yards and 1 INT. Alvin Kamara led the team in rushing yards with 21. Rashid Shaheed led the receivers with 75 receiving yards on 9 receptions. Demario Davis led the defense in that game with 4 solo tackles and 7 assisted tackles while Chase Young led the defense in sacks with 1.5. No one on the defense came away with an interception for them in that one.
The Rams are entering this game with a 5-2 record overall and they have a 0-1 record in their divisional games too. They are 2-1 in their home games, 2-1 in their road games, and they are also 1-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Jacksonville Jaguars 35-7. Matthew Stafford was the starting QB and he completed 21/33 passes for 182 passing yards, 5 touchdowns, and 0 interceptions. Kyren Williams led the team in rushing yards with 54. Colby Parkinson led the receivers with 47 receiving yards on 3 receptions. Kamren Curl led the defense in that game with 8 solo tackles and 2 assisted tackles while Nate Landman and Byron Young each led the defense in sacks with 1.5. No one on the defense came away with an interception for them in that one.
Saints vs Rams Prediction
The current betting odds have the Rams listed as a 14 point favorite in this game according to Draftkings Sportsbook. The Rams have looked really good in their games this season with their 5-2 record overall which has them right near the top of the NFC West. They are off a 35-7 win over the Jaguars in their last one and they have been starting to roll in their games lately. They are also coming out of their bye week so they have some extra rest for this game. Meanwhile, the Saints have looked terrible in their games this season with their 1-7 record overall which has them right at the bottom of the NFC South with one of the worst records in the entire NFL. They are off a 23-3 loss at home to the Bucs in their last one and they finally made a change at QB in that one. They benched Rattler for Shough, but he wasn't any better in the offense and this team has a lot more issues than just their quarterback. The Saints have also looked a lot better in their home games this year, but they are 0-3 in their road games with some much worse losses too. This is a game between one of the worst teams in the NFL this year and a team that is a Super Bowl contender. The Rams are going to come out of their bye week strong and keep rolling against another bad team here. The best way to place a bet here is on the Rams to cover the spread in this game.
Saints Rams Prediction: Our NFL Pick for Sunday, November 2, 2025 (4:05 pm ET start time) is Rams 38 Saints 6.
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NFL Betting Trends
New Orleans Saints: 0-5 ATS against NFC West division opponents. 15-26 ATS in all games. 2-8 ATS when playing against a good team (Win Pct. 60% to 75%). 25-17 UNDER in all games. 6-1 UNDER after a game with a turnover margin of -2 or worse.
Los Angeles Rams: 26-16 ATS in all games. 15-7 ATS as a favorite. 7-2 ATS after allowing 14 points or less last game. 9-3 UNDER as a home favorite. 10-4 UNDER when playing against a team with a losing record.
Key Injuries
New Orleans Saints: D. Godchaux (DL) Injured - Rest. A. Kamara (RB) Injured - Ankle. J. Johnson (TE) Injured - Neck. R. Shaheed (WR) Injured - Hip. C. Olave (WR) Injured - Ankle. A. Taylor (CB) Injured - Shoulder. D. Neal (RB) Injured - Ankle.
Los Angeles Rams: R. Havenstein (OG) Injured - Ankle. D. Williams (CB) Injured - Shoulder. P. Nacua (WR) Injured - Ankle. K. Kinchens (S) Injured - Toe.
Notable Quotes
“I love Spence. I love Tyler. I love these guys to death. These are never easy things. We’re just trying to find a formula that works to our advantage.” - Kellen Moore after his team’s loss against the Buccaneers in their last game.
“We spread the ball around a bunch today.” - Matt Stafford after their win against the Jaguars in their last game.
Starting Lineups
New Orleans Saints
WR Olave, Chris
WR Cooks, Brandin
WR Shaheed, Rashid
TE Johnson, Juwan
QB Shough, Tyler
RB Kamara, Alvin
Los Angeles Rams
WR Adams, Davante
WR Nacua, Puka
WR Whittington, Jordan
TE Higbee, Tyler
QB Stafford, Matthew
RB Williams, Kyren
Statistical Leaders
New Orleans Saints
Passing: Spencer Rattler (1,586)
Rushing: Alvin Kamara (363)
Receiving: Chris Olave (503)
Touchdowns: Chris Olave (3)
Los Angeles Rams
Passing: Matthew Stafford (1,866)
Rushing: Kyren Williams (472)
Receiving: Puka Nacua (616)
Touchdowns: Davante Adams (6)
Coaches:
New Orleans Saints: Kellen Moore (1st season)
Los Angeles Rams: Sean McVay (9th season)