Minnesota Twins vs Seattle Mariners Prediction, Preview and Odds - 07/31/2026

Game Time: 10:10 pm ET, Friday, July 31, 2026

Venue:  T-Mobile Park, Seattle, WA

Where to Watch:  MLB TV

DraftKings:  Moneyline odds:  Twins +153, Mariners -186; Over/Under:  8 runs

Bet365:  Moneyline odds:  Twins +155, Mariners -185; Over/Under:  8 runs

BetMGM:  Moneyline odds:  Twins +155, Mariners -190; Over/Under:  8 runs

Minnesota Twins:  54-55 (3rd place, AL Central)

Seattle Mariners:  53-56 (3rd place, AL West)

Do not miss out on our expert handicapper analysis! Tom Stryker is on a HOT STREAK in MLB on a 9-2 MLB RUN for +$6,520 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.

Minnesota Twins:  5-5 last 10

Seattle Mariners:  4-6 last 10

The Twins are entering this series off a loss and lost their 3-game series against the Kansas City Royals 2-1 in their last series. They enter this game with a 54-56 record overall and have a road record of 25-28. This is the series opener of a 3-game series with the Mariners on Friday. Their offense ranks 13th in the MLB with a .725 OPS. Bailey Ober was their starting pitcher on Thursday while Zebby Matthews is making his start in this game on Friday. He is 4-8 with a 5.21 ERA this season. His team lost their last 3 straight games this season with him making an appearance. In his last MLB regular season appearance, he allowed 2 ER, 0 HR, and 3 BB with 1 SO on 3 hits through 6 IP against the Athletics.

The Mariners lost their 4-game series against the Texas Rangers 3-1. They enter this game with a 53-56 record overall and have a home record of 30-23. This is the 1st game of a 3-game series with the Twins on Friday with the series finale of their series against the Los Angeles Dodgers still to be played on Thursday. The Mariners won the 1st game of that series on Tuesday and lost the 2nd game on Wednesday. Their offense ranks 27th in the MLB with a .688 OPS. Bryan Woo is their starting pitcher on Thursday while Bryce Miller is making his start in this game on Friday. He is 4-5 with a 2.75 ERA this season. His team lost their last 3 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 5 earned runs, 2 homers, and 1 walk with 0 strikeouts on 6 hits through 5.1 innings pitched against the Texas Rangers.

The current betting odds have the Mariners listed as a favorite in this game according to Draftkings Sportsbook. The Mariners haven't looked great in their games this season with their 53-56 record overall which has them right in the middle of the AL West. They have looked a lot better in their own ballpark though with their 30-23 home record this season. Meanwhile, the Twins haven't looked great in their games this season with their 54-56 record overall which has them right in the middle of the AL Central. They haven't been a good road team either with their 25-28 road record this year. The Twins are 5-5 in their last 10 games while the Mariners are 4-6 in their last 10, but the Mariners are going to be desperate in this series. They were leading the AL West not too long ago and have been slipping lately, but they are going to have the better pitching matchup in this one and they can take advantage of that. The Mariners are going with Miller in this one and he has looked great this season. He is 4-5 with a 2.75 ERA and he has been their best starter. He did give up 5 earned runs in his last start and the team has lost 3 games in a row now with him starting, but that hasn't been a common theme for him this year and he has also looked a lot better in his home starts. The Twins are going with Matthews in this one and he hasn't looked great this season. He is 4-8 with a 5.21 ERA and he has been giving up a lot of runs all season. He only gave up 2 earned runs in his last start, but that hasn't been a common theme for him lately and the team has been having a lot of trouble with him too, losing 3 games in a row now with him starting. He hasn't looked nearly as good in his road starts either while the Mariners have looked a lot better at home this season as a team. Look for the Mariners to take advantage of this pitching matchup at home and bounce back. The best way to place a bet here is on the Mariners to win this game. 

Twins Mariners Prediction:  Our MLB Pick for Friday, July 31, 2026 (10:10 pm ET start time) is Mariners 5 Twins 0.

Don't miss our champion handicappers free picks, best bets, and expert baseball picks today.  And if you enjoyed this Minnesota Twins Seattle Mariners prediction, be sure to drop by every day for our daily MLB projections and previews.

Minnesota Twins: 50-32 (+13.2 units) on the moneyline against AL West opponents. 123-99 (+15.9 units) on the moneyline vs. an AL team with a slugging percentage .410 or worse on the season. 103-78 (+16.9 units) on the moneyline vs. AL teams scoring 4.4 or less runs/game on the season. 18-4 OVER when the total is 7 to 7.5. 33-18 OVER in road games.

Seattle Mariners: 49-46 (-6.7 units) on the moneyline against AL Central opponents. 234-212 (-17.1 units) on the moneyline in all games. 171-136 (-16.4 units) on the moneyline as a favorite of -110 or higher. 31-19 OVER when the total is 7 to 7.5. 11-3 OVER as a home favorite of -150 to -200.

Minnesota Twins:  B. Buxton (CF) Ten Day IL - Hip. C. Sands (RP) Fifteen Day IL - Elbow. M. Paredes (SP) Fifteen Day IL - Oblique. A. Banda (RP) Sixty Day IL - Lat. M. Abel (SP) Sixty Day IL - Elbow. G. Acton (RP) Sixty Day IL - Shoulder. D. Festa (SP) Sixty Day IL - Shoulder. P. Lopez (SP) Sixty Day IL - Elbow.

Seattle Mariners:  W. Wilson (3B) Sixty Day IL - Thumb. M. Brash (RP) Fifteen Day IL - Lat. C. Criswell (RP) Sixty Day IL - Shoulder. B. Donovan (3B) Ten Day IL - Groin. C. Vargas (RP) Sixty Day IL - Lat. L. Evans (SP) Sixty Day IL - Arm.

“He left some balls in the middle of the plate. The one inning he was able to get out of it, the first and third, but after that [he] just left some balls in the middle, and they capitalized.” - Derek Shelton after his team’s loss against the Royals in their game on Wednesday.

“Yesterday, we found a lot of barrels; today, a lot of contact, just not a lot of barrels and a couple of walks to get us some traffic here and there. But outside of that, just not much going.” - Dan Wilson after his team’s loss against the LA Dodgers in their game on Wednesday.

Austin Martin (R) LF

Ryan Jeffers (R) C

Royce Lewis (R) 2B

Josh Bell (S) DH

Kody Clemens (L) RF

Luke Keaschall (R) CF

Brooks Lee (S) 3B

Alex Jackson (R) 1B

Ryan Kreidler (R) SS

Cole Young (L) 2B

Randy Arozarena (R) LF

Julio Rodríguez (R) CF

Dominic Canzone (L) RF

Cal Raleigh (S) C

Josh Naylor (L) 1B

Rob Refsnyder (R) DH

Weston Wilson (R) 3B

Colt Emerson (L) SS

Batting Average:  Gabriel Gonzalez (.500)

Hits:  Josh Bell (94)

Home Runs:  Byron Buxton (25)

RBI:  Josh Bell (63)

Stolen Bases:  Luke Keaschall (13)

Wins:  Taj Bradley (9)

Saves:  Yoendrys Gómez (12)

ERA:  Jack Anderson (0.00)

Batting Average:  Randy Arozarena (.278)

Hits:  Josh Naylor (104)

Home Runs:  Dominic Canzone (18)

RBI:  Dominic Canzone (49)

Stolen Bases:  Josh Naylor (21)

Wins:  George Kirby (8)

Saves:  Andrés Muñoz (19)

ERA:  Matt Brash (0.54)

Managers:

Minnesota Twins: Derek Shelton (1st season)

Seattle Mariners: Dan Wilson (3rd season)