Minnesota Twins vs Houston Astros Prediction, Preview and Odds - 06/13/2025

Game Time: 8:10 pm ET, Friday, June 13, 2025

Venue:  Daikin Park, Houston, TX 

Where to Watch:  SCHN

DraftKings:  Moneyline odds:  Twins -102, Astros -119; Over/Under:  8 runs

Bet365:  Moneyline odds:  Twins +100, Astros -120; Over/Under:  8 runs

BetMGM:  Moneyline odds:  Twins +100, Astros -120; Over/Under:  8 runs

Minnesota Twins:  36-31 (2nd place, AL Central)

Houston Astros:  37-30 (1st place, AL West)

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Minnesota Twins:  5-5 last 10

Houston Astros:  6-4 last 10

The Twins lost their 3-game series against the Toronto Blue Jays 2-1. They enter this game with a 36-31 record overall and have a road record of 16-20. This is the series opener of a 3-game series with the Astros on Friday with the series finale of their series against the Texas Rangers still to be played on Thursday. The Twins lost the series opener of that series on Tuesday and won the 2nd game on Wednesday. Their offense ranks 15th in the MLB with a .707 OPS. Bailey Ober is their starting pitcher on Thursday while Chris Paddack is making his start in this game on Friday. He is 2-5 with a 3.53 ERA this season. His team lost their last 4 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 2 ER, 1 HR, and 2 BB with 2 SO on 4 hits through 6 IP against the Toronto Blue Jays.

The Astros won their 3-game series against the Cleveland Guardians 2-1. They enter this game with a 37-30 record overall and have a home record of 23-13. This is the 1st game of a 3-game series with the Twins on Friday with the series finale of their series against the Chicago White Sox still to be played on Thursday. The Astros lost the 1st game of that series on Tuesday and won the 2nd game on Wednesday. Their offense ranks 14th in the MLB with a .708 OPS. Framber Valdez is their starting pitcher on Thursday while rookie pitcher Colton Gordon is making his start in this game on Friday. He is 1-1 with a 5.11 ERA this season. His team won 4 of their last 5 games this season with him making an appearance. In his last MLB regular season start, he allowed 1 earned run, 0 homers, and 0 walks with 5 strikeouts on 7 hits through 5 innings pitched against the Cleveland Guardians.

The current betting odds have the Twins listed as a slight underdog in this game according to Draftkings Sportsbook. The Twins have looked good in their games this season with their 36-31 record overall which has them right near the top of the AL Central. They haven't been a great road team though with their 16-20 road record this season. Meanwhile, the Astros have looked good in their games this season with their 37-30 record overall which has them right at the top of the AL West. They have looked a lot better in their own ballpark too with their 23-13 home record. Neither team has a good starter going in this game though and that is something that the Twins can take advantage of since they do have the more reliable arm in this one. Paddack is on the mound for the Twins and he has been up and down this year, but lately he has looked better. He is 2-5 with a 3.53 ERA and he hasn't been giving up a ton of runs lately. His team has lost 4 games in a row now with him starting, but he only gave up 2 earned runs in his last start and is still the better option here. The Astros are going with Gordon in this one and he hasn't looked good in his debut season. He is 1-1 with a 5.11 ERA and has been giving up a ton of runs in his starts this year. His team has surprisingly won 4 of the last 5 games he started in and he only gave up 1 earned run in his last start, but that hasn't been a common theme for him this year and he won't string together 2 starts like that. The best way to place a bet here is on the Twins to win this game. 

Twins Astros Prediction:  Our MLB Pick for Friday, June 13, 2025 (8:10 pm ET start time) is Twins 7 Astros 5.

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Minnesota Twins: 54-29 (+20 units) on the moneyline against AL West opponents. 113-79 (+10.5 units) on the moneyline vs. an AL team with a slugging percentage .410 or worse on the season. 100-62 (+14.2 units) on the moneyline vs. AL teams scoring 4.4 or less runs/game on the season. 25-13 UNDER vs. a team with a good bullpen whose WHIP is 1.350 or better.

Houston Astros: 46-40 (-12.1 units) on the moneyline against AL Central opponents. 221-180 (-12.4 units) on the moneyline in all games. 109-96 (-33.3 units) on the moneyline in home games. 17-8 UNDER vs. an AL starting pitcher whose WHIP is 1.300 or better.

Minnesota Twins:  P. Lopez (SP) Sixty Day IL - Shoulder. Z. Matthews (SP) Fifteen Day IL - Shoulder. L. Keaschall (2B) Sixty Day IL - Forearm. M. Tonkin (RP) Sixty Day IL - Shoulder.

Houston Astros:  Z. Dezenzo (RF) Ten Day IL - Hand. R. Blanco (SP) Sixty Day IL - Elbow. C. McCormick (LF) Ten Day IL - Oblique. H. Wesneski (RP) Sixty Day IL - Elbow. Y. Alvarez (LF) Ten Day IL - Hand. S. Arrighetti (SP) Fifteen Day IL - Thumb. L. Garcia (SP) Sixty Day IL - Elbow. C. Javier (SP) Sixty Day IL - Elbow. P. Leon (RF) Ten Day IL - Knee. J. France (SP) Sixty Day IL - Shoulder. T. Trammell (LF) Ten Day IL - Calf.

“We saw some things from our center fielder that you probably won't forget. Pat on the back to everyone who was at the ballpark tonight to be able to watch what he did out there. One of the more mesmerizing performances that you'll ever see on a field.” - Rocco Baldelli after his team’s win against the Rangers in their game on Wednesday.

“It’s trusting the process and having the confidence that at some point this is going to turn, and that’s what I see out of Walker. He knows this tide will turn for him. June, July and August have always been the best months of his career.” - Joe Espada after his team’s win against the White Sox in their game on Wednesday.

Byron Buxton (R) CF

Ryan Jeffers (R) C

Carlos Correa (R) SS

Ty France (R) 1B

Royce Lewis (R) DH

Willi Castro (S) RF

Brooks Lee (S) 2B

Jonah Bride (R) 3B

Harrison Bader (R) LF

Jeremy Peña (R) SS

Isaac Paredes (R) 3B

Jose Altuve (R) 2B

Yainer Diaz (R) C

Christian Walker (R) 1B

Victor Caratini (S) DH

Jake Meyers (R) CF

Cam Smith (R) RF

Jacob Melton (L) LF

Batting Average:  Luke Keaschall (.368)

Hits:  Ty France (66)

Home Runs:  Byron Buxton (11)

RBI:  Byron Buxton (41)

Stolen Bases:  Byron Buxton (11)

Wins:  Joe Ryan (7)

Saves:  Jhoan Duran (10)

ERA:  Danny Coulombe (0.00)

Batting Average:  Jeremy Peña (.322)

Hits:  Jeremy Peña (83)

Home Runs:  Isaac Paredes (14)

RBI:  Isaac Paredes (41)

Stolen Bases:  Jeremy Peña (14)

Wins:  Hunter Brown (8)

Saves:  Josh Hader (17)

ERA:  Josh Hader (1.29)

Managers:

Minnesota Twins: Rocco Baldelli (7th season)

Houston Astros: Joe Espada (2nd season)