Minnesota Twins vs Arizona Diamondbacks Prediction, Preview and Odds - 06/19/2026

Game Time: 9:45 pm ET, Friday, June 19, 2026

Venue:  Chase Field, Phoenix, AZ

Where to Watch:  Apple TV

DraftKings:  Moneyline odds:  Twins +141, Diamondbacks -171; Over/Under:  8.5 runs

Bet365:  Moneyline odds:  Twins +145, Diamondbacks -175; Over/Under:  8.5 runs

BetMGM:  Moneyline odds:  Twins +145, Diamondbacks -175; Over/Under:  8.5 runs

Minnesota Twins:  35-40 (3rd place, AL Central)

Arizona Diamondbacks:  38-36 (3rd place, NL West)

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Minnesota Twins:  5-5 last 10

Arizona Diamondbacks:  5-5 last 10

The Twins are entering this series off a win and completed the sweep in their 3-game series against the Texas Rangers 3-0 in their last series. They enter this game with a 35-40 record overall and have a road record of 15-21. This is the series opener of a 3-game series with the Diamondbacks on Friday. Their offense ranks 13th in the MLB with a .725 OPS. Joe Ryan was their starting pitcher on Thursday while rookie pitcher Connor Prielipp is making his start in this game on Friday. He is 2-4 with a 5.26 ERA this season. His team lost their last 2 straight games this season with him making an appearance. In his last MLB regular season appearance, he allowed 4 ER, 1 HR, and 2 BB with 2 SO on 7 hits through 6 IP against the St Louis Cardinals.

The Diamondbacks are entering this series off a win and won their 3-game series against the Los Angeles Angels 2-1 in their last series. They enter this game with a 38-36 record overall and have a home record of 23-15. This is the 1st game of a 3-game series with the Twins on Friday and they have Thursday off as a day of rest. Their offense ranks 26th in the MLB with a .691 OPS. Eduardo Rodríguez was their starting pitcher on Wednesday while Michael Soroka is making his start in this game on Friday. He is 8-3 with a 3.11 ERA this season. His team lost 2 of their last 3 games this season with him making an appearance. In his last MLB regular season start, he allowed 1 earned run, 0 homers, and 0 walks with 7 strikeouts on 2 hits through 7 innings pitched against the Cincinnati Reds.

The current betting odds have the Diamondbacks listed as a favorite in this game according to Draftkings Sportsbook. The Diamondbacks have looked good in their games this season with their 38-36 record overall which has them right in the middle of the NL West. They have looked a lot better in their own ballpark though with their 23-15 home record this season. Meanwhile, the Twins haven't looked great in their games this season with their 35-40 record overall which has them right near the bottom of the AL Central. They haven't been a good road team either with their 15-21 road record this year. Neither team has looked great this season with both being 5-5 in their last 10 games respectively, but the Diamondbacks do have the better pitching matchup here. The Diamondbacks are going with Soroka in this one and he has looked great this season. He is 8-3 with a 3.11 ERA and he hasn't been giving up many runs all year. His team has had more trouble with him lately, losing 2 of their last 3 games with him starting, but that hasn't been a common theme for them this year. He is also coming off another great start in which he gave up 1 earned run. The Twins are going with Prielipp in this one and he hasn't looked great this season. He is 2-4 with a 5.26 ERA and he has had a lot of trouble in this rookie season. He just gave up 4 earned runs in his last start which has become a common theme for him lately, and the team has lost 2 games in a row now with him starting too. The Diamondbacks have looked a lot better at home this season, so look for them to take advantage of this pitching matchup. The best way to place a bet here is on the Diamondbacks to win this game. 

Twins Diamondbacks Prediction:  Our MLB Pick for Friday, June 19, 2026 (9:45 pm ET start time) is Diamondbacks 6 Twins 2.

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Minnesota Twins: 187-212 (-48.4 units) on the moneyline in all games. 86-112 (-23.4 units) on the moneyline in road games. 64-93 (-11.9 units) on the moneyline as an underdog of +100 or higher. 30-15 OVER as an underdog of +100 or higher.

Arizona Diamondbacks: 110-86 (-12.1 units) on the moneyline as a favorite of -110 or higher. 44-56 (-12.1 units) on the moneyline vs. a starting pitcher who gives up 0.5 or less HR's/start. 94-80 (-7.7 units) on the moneyline when playing against a team with a losing record. 23-11 OVER against AL Central opponents.

Minnesota Twins:  B. Ober (SP) Fifteen Day IL - Elbow. K. Rojas (SP) Fifteen Day IL - Elbow. R. Jeffers (C) Ten Day IL - Hand. G. Acton (RP) Sixty Day IL - Shoulder. C. Sands (RP) Fifteen Day IL - Forearm. M. Abel (SP) Fifteen Day IL - Elbow. D. Festa (SP) Sixty Day IL - Shoulder. P. Lopez (SP) Sixty Day IL - Elbow.

Arizona Diamondbacks:  C. Santana (1B) Sixty Day IL - Groin. J. McCann (C) Ten Day IL - Quad. C. Mena (SP) Sixty Day IL - Shoulder. B. Walston (SP) Sixty Day IL - Elbow. C. Burnes (SP) Sixty Day IL - Elbow. A. Puk (RP) Sixty Day IL - Elbow. J. Martinez (RP) Sixty Day IL - Elbow. A. Weber (RP) Sixty Day IL - Shoulder.

"He takes really aggressive swings and I mean, he does a really good job pull side in the air because of the way he can back spin the baseball." - Derek Shelton on Kody Clemens after his team’s win against the Rangers in their game on Tuesday.

“I think the dugout felt an immediate sigh of relief and took the air out of some very tense moments and games over the past 12, 14 days. And that’s what we want guys to do. We want them to come up, build an inning, see pitches, have their type of at-bat and then when the right person in the right situation comes up and slugs and breaks the game open, it’s not by accident.” - Torey Lovullo after his team’s win against the LA Angels in their game on Wednesday. 

Trevor Larnach (L) LF

Byron Buxton (R) CF

Kody Clemens (L) RF

Royce Lewis (R) 1B

Josh Bell (S) DH

Brooks Lee (S) 3B

Victor Caratini (S) C

Tristan Gray (L) SS

Luke Keaschall (R) 2B

Ketel Marte (S) DH

Geraldo Perdomo (S) SS

Corbin Carroll (L) RF

Gabriel Moreno (R) C

Nolan Arenado (R) 3B

Ildemaro Vargas (S) 2B

Jordan Lawlar (R) CF

LuJames Groover (R) 1B

Tommy Troy (R) LF

Batting Average:  Gabriel Gonzalez (.500)

Hits:  Byron Buxton (71)

Home Runs:  Byron Buxton (23)

RBI:  Josh Bell (45)

Stolen Bases:  Luke Keaschall (10)

Wins:  Bailey Ober (6)

Saves:  Yoendrys Gómez (6)

ERA:  Kendry Rojas (1.26)

Batting Average:  Jordan Lawlar (.294)

Hits:  Corbin Carroll (73)

Home Runs:  Corbin Carroll (13)

RBI:  Ketel Marte (43)

Stolen Bases:  Geraldo Perdomo (11)

Wins:  Michael Soroka (8)

Saves:  Paul Sewald (18)

ERA:  Taylor Clarke (2.05)

Managers:

Minnesota Twins: Derek Shelton (1st season)

Arizona Diamondbacks: Torey Lovullo (10th season)