Milwaukee Brewers vs St Louis Cardinals Prediction, Preview and Odds - 07/08/2026

Game Time: 7:45 pm ET, Wednesday, July 8, 2026

Venue:  Busch Stadium, St. Louis, MO

Where to Watch:  MLB TV

DraftKings:  Moneyline odds:  Brewers -131, Cardinals +109; Over/Under:  8 runs

Bet365:  Moneyline odds:  Brewers -130, Cardinals +110; Over/Under:  8 runs

BetMGM:  Moneyline odds:  Brewers -135, Cardinals +110; Over/Under:  8 runs

Milwaukee Brewers:  56-33 (1st place, NL Central)

St Louis Cardinals:  47-41 (3rd place, NL Central)

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Milwaukee Brewers:  6-4 last 10

St Louis Cardinals:  5-5 last 10

The Brewers are entering this series off a win and won their 3-game series against the Arizona Diamondbacks 2-1 in their last series. They enter this game with a 56-33 record overall and have a road record of 27-15. This is the 4th game of a 5-game series with the Cardinals on Wednesday with the 2nd game and the 3rd game still to be played on Tuesday in a double-header. The Brewers won the series opener on Monday. Their offense ranks 11th in the MLB with a .733 OPS. Jacob Misiorowski is one of their starting pitchers on Tuesday while Kyle Harrison is making his start in this game on Wednesday. He is 8-1 with a 2.82 ERA this season. His team lost 2 of their last 3 games this season with him making an appearance. In his last MLB regular season appearance, he allowed 3 ER, 0 HR, and 1 BB with 3 SO on 5 hits through 2.2 IP against the Arizona Diamondbacks.

The Cardinals are entering this series off a loss and won their 3-game series against the Chicago Cubs 2-1 in their last series. They enter this game with a 47-41 record overall and have a home record of 23-22. This is the 4th game of a 5-game series with the Brewers on Wednesday with the 2nd game and the 3rd game of this series still to be played on Tuesday. The Cardinals lost the 1st game of this series on Monday. Their offense ranks 16th in the MLB with a .719 OPS. Matt Svanson is one of their starting pitchers on Tuesday while Michael McGreevy is making his start in this game on Wednesday. He is 3-7 with a 3.12 ERA this season. His team lost their last 4 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 2 earned runs, 1 homer, and 1 walk with 3 strikeouts on 3 hits through 6 innings pitched against the Atlanta Braves.

The current betting odds have the Brewers listed as a favorite in this game according to Draftkings Sportsbook. The Brewers have looked great in their games this season with their 56-33 record overall which has them right at the top of the NL Central with one of the best records in MLB. They have been a great road team too with their 27-15 road record this year. Meanwhile, the Cardinals have looked good in their games this season with their 47-41 record overall which has them right in the middle of the NL Central. They have looked good in their own ballpark too with their 23-22 home record this season. The Cardinals just worked their way out of a big slump over the last 2 weeks, but they are still just 5-5 in their last 10 games while the Brewers are 6-4 in their last 10 and have been one of the best teams in the league all season. The Cardinals are going with McGreevy in this one and he has looked great this season. He is 3-7 with a 3.12 ERA, but the team hasn’t had a ton of success with him lately. He only gave up 2 earned runs in his last start, but his team has lost 4 games in a row now with him starting. The team hasn't been putting up a ton of runs on offense lately either and the Brewers do have the better bullpen to help out too. The Brewers are going with Harrison in this one and he has looked great this season too. He is 8-1 with a 2.82 ERA and he hasn't been giving up many runs at all this season. He did give up 3 earned runs in his last start, but that hasn't been a common theme for him. He will be looking to bounce back with a better performance, especially since the team has lost 2 of their last 3 games with him starting, and the Brewers do have the better offense to give them the edge. Between the offense and the bullpen, the Brewers should have the edge in this one and will continue to roll in this important divisional series. The best way to place a bet here is on the Brewers to win this game. 

Brewers Cardinals Prediction:  Our MLB Pick for Wednesday, July 8, 2026 (7:45 pm ET start time) is Brewers 3 Cardinals 2.

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Milwaukee Brewers: 250-176 (+49.8 units) on the moneyline in all games. 119-91 (+31.6 units) on the moneyline in road games. 82-49 (+24.3 units) on the moneyline against division opponents. 14-7 UNDER against division opponents. 

St Louis Cardinals: 97-93 (-3.4 units) on the moneyline vs. an NL team with a slugging percentage .400 or worse on the season. 12-15 (-2.6 units) on the moneyline when playing against a top-level team (Win Pct. > 62%). 135-150 (-8 units) on the moneyline vs. a team with a good bullpen whose WHIP is 1.350 or better. 30-16 UNDER when playing against a team with a winning record.

Milwaukee Brewers:  D. Hamilton (SS) Day To Day - Hamstring. J. Kuhnel (RP) Fifteen Day IL - Shoulder. B. Woodruff (SP) Fifteen Day IL - Shoulder. Q. Priester (SP) Sixty Day IL - Wrist. C. Crow (SP) Fifteen Day IL - Forearm. B. Fitzpatrick (RP) Sixty Day IL - Elbow. C. Rodriguez (RP) Fifteen Day IL - Shoulder. D. Hall (RP) Fifteen Day IL - Pectoral. R. Zastryzny (RP) Fifteen Day IL - Shoulder. A. Zerpa (RP) Sixty Day IL - Forearm. L. Henderson (SP) Fifteen Day IL - Back. B. Lockridge (LF) Ten Day IL - Knee.

St Louis Cardinals:  J. Bruihl (RP) Day To Day - Ankle. M. Rajcic (SP) Ten Day IL - Elbow. R. Urias (3B) Sixty Day IL - Elbow.

“If I was to tell you after a game that the first four in the order were to have one hit, and I was to tell you we were going to make three defensive miscues, who would you take? It’s a testament to the guys.” - Pat Murphy after his team’s win against the Cardinals in their game on Monday.

“We know it’s going to be tough with where our pitching’s at. We don’t have everybody available at the moment. Which, when you get late in the games, someone has to step up and get it done. Unfortunately, that’s just part of it as you get closer to the break. Guys are needing extra time to recover. So, we didn’t have our main guys at the back end, and we couldn’t close it out.” - Oliver Marmol after his team’s loss against the Brewers in their game on Monday. 

Christian Yelich (L) DH

Jackson Chourio (R) LF

Brice Turang (L) 2B

William Contreras (R) C

Jake Bauers (L) 1B

Garrett Mitchell (L) CF

Sal Frelick (L) RF

Cooper Pratt (R) SS

David Hamilton (L) 3B

JJ Wetherholt (L) 2B

Iván Herrera (R) DH

Jordan Walker (R) RF

Nelson Velázquez (R) LF

José Fermín (R) 3B

Masyn Winn (R) SS

Nathan Church (L) CF

Blaze Jordan (R) 1B

Pedro Pagés (R) C

Batting Average:  Tyler Black (.333)

Hits:  William Contreras (95)

Home Runs:  Jake Bauers (16)

RBI:  Jake Bauers (54)

Stolen Bases:  David Hamilton (18)

Wins:  Aaron Ashby (12)

Saves:  Trevor Megill (14)

ERA:  Easton McGee (0.00)

Batting Average:  Jordan Walker (.290)

Hits:  Jordan Walker (96)

Home Runs:  Jordan Walker (20)

RBI:  Jordan Walker (67)

Stolen Bases:  Jordan Walker (11)

Wins:  Andre Pallante (10)

Saves:  Riley O'Brien (22)

ERA:  Jared Shuster (2.35)

Managers:

Milwaukee Brewers: Pat Murphy (3rd season)

St Louis Cardinals: Oliver Marmol (5th season)