Milwaukee Brewers vs Cincinnati Reds Prediction, Preview and Odds - 06/23/2026

by Rod Pearson

Monday, Jun 22, 2026
Game Time: 7:10 pm ET, Tuesday, June 23, 2026
Venue:  Great American Ball Park, Cincinnati, OH
Where to Watch:  MLB TV


Opening Odds at USA Sportsbooks

DraftKings:  Moneyline odds:  Brewers -120, Reds +100; Over/Under:  9.5 runs
Bet365:  Moneyline odds:  Brewers -120, Reds +100; Over/Under:  9.5 runs
BetMGM:  Moneyline odds:  Brewers -120, Reds +100; Over/Under:  9.5 runs

Season Record

Milwaukee Brewers:  46-29 (1st place, NL Central)
Cincinnati Reds:  37-39 (5th place, NL Central)

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Recent Form
Milwaukee Brewers:  5-5 last 10
Cincinnati Reds:  5-5 last 10



Milwaukee Brewers vs Cincinnati Reds Preview and Analysis


The Brewers are entering this series off a win and lost their 3-game series against the Atlanta Braves 2-1 in their last series. They enter this game with a 46-29 record overall and have a road record of 21-14. This is the 2nd game of a 3-game series with the Reds on Tuesday with the series opener still to be played on Monday. Their offense ranks 9th in the MLB with a .734 OPS. Brandon Woodruff is their starting pitcher on Monday while Brandon Sproat is making his start in this game on Tuesday. He is 1-4 with a 5.94 ERA this season. His team won 2 of their last 3 games this season with him making an appearance. In his last MLB regular season appearance, he allowed 4 ER, 1 HR, and 2 BB with 6 SO on 2 hits through 3.2 IP against the Cleveland Guardians.

The Reds are entering this series off a win and won their 3-game series against the New York Yankees 2-1 in their last series. They enter this game with a 37-39 record overall and have a home record of 19-19. This is the 2nd game of a 3-game series with the Brewers on Tuesday with the 1st game of this series still to be played on Monday. Their offense ranks 21st in the MLB with a .706 OPS. Brady Singer is their starting pitcher on Monday while Nick Lodolo is making his start in this game on Tuesday. He is 2-2 with a 6.12 ERA this season. His team lost their last 3 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 7 earned runs, 0 homers, and 2 walks with 2 strikeouts on 11 hits through 4.2 innings pitched against the New York Mets.


Brewers vs Reds Prediction

The current betting odds have the Brewers listed as a slight favorite in this game according to Draftkings Sportsbook. The Brewers have looked great in their games this season with their 46-29 record overall which has them right at the top of the NL Central with one of the best records in MLB. They have been a good road team too with their 21-14 road record this year. Meanwhile, the Reds haven't looked great in their games this season with their 37-39 record overall which has them right at the bottom of the NL Central. They haven't looked great in their own ballpark either with their 19-19 home record this season. Both of these teams are 5-5 in their last 10 games respectively, but the Brewers have been one of the best teams over the last month while the Reds have stayed afloat for most of the season, but lately they are starting to trend the opposite way. They just won their last series over the Yankees, but they aren't going to have great pitching in this series now. Lodolo is starting for the Reds in this one and he has looked terrible this season. He is 2-2 with a 6.12 ERA and his team hasn't had a ton of success with him either. They have lost 3 games in a row now with him starting and he is coming off another bad start in which he gave up 7 earned runs, something that has been a common theme for him this year. The Brewers are going with Sproat in this one and he hasn't looked any better this season. He is 1-4 with a 5.94 ERA and has also been giving up a ton of runs. He is coming off another bad start in which he gave up 4 earned runs, but the team has won 2 of their last 3 games with him starting now and they do have a really good bullpen to help out. The Brewers have been the steadier team all season compared to the Reds, and they also have the much better offense with the way the Brewers have been putting up runs lately. The best way to place a bet here is on the Brewers to win this game. 

Brewers Reds Prediction:  Our MLB Pick for Tuesday, June 23, 2026 (7:10 pm ET start time) is Brewers 8 Reds 6.
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MLB Betting Trends


Milwaukee Brewers: 240-172 (+46.4 units) on the moneyline in all games. 113-90 (+27.2 units) on the moneyline in road games. 145-89 (+18.6 units) on the moneyline as a favorite of -110 or higher. 4-0 OVER vs. an NL starting pitcher whose ERA is 5.40 or worse.

Cincinnati Reds: 196-205 (-5.7 units) on the moneyline in all games. 102-97 (-11.3 units) on the moneyline in home games. 74-96 (-7.9 units) on the moneyline as an underdog of +100 to +150. 20-7 OVER when the total is 9 to 9.5.

Key Injuries


Milwaukee Brewers:  Q. Priester (SP) Sixty Day IL - Wrist. B. Sproat (SP) Day To Day - Hamstring. C. Crow (SP) Fifteen Day IL - Forearm. B. Fitzpatrick (RP) Sixty Day IL - Elbow. C. Rodriguez (RP) Fifteen Day IL - Shoulder. D. Hall (RP) Fifteen Day IL - Pectoral. R. Zastryzny (RP) Fifteen Day IL - Shoulder. A. Zerpa (RP) Sixty Day IL - Forearm. L. Henderson (SP) Fifteen Day IL - Back. B. Lockridge (LF) Ten Day IL - Knee. B. Woodruff (SP) Fifteen Day IL - Arm. J. Koenig (RP) Fifteen Day IL - Elbow.

Cincinnati Reds:  E. De La Cruz (SS) Ten Day IL - Hamstring. P. Johnson (RP) Fifteen Day IL - Elbow. G. Ashcraft (RP) Sixty Day IL - Forearm. K. Hayes (3B) Ten Day IL - Back. E. Pagan (RP) Fifteen Day IL - Hamstring. B. Williamson (SP) Sixty Day IL - Shoulder. H. Greene (SP) Sixty Day IL - Elbow.


Notable Quotes


“We challenged him, and he took it well. It was about belief, you know? Start to believe. I don’t know if it helped him. I have no idea if he even heard me. But he pitched better. It was big for us today.” - Pat Murphy after his team’s win against the Braves in their game on Sunday. 


"I think he's a really smart kid to boot. He's aware of everything. I think one of our challenges is not giving him too much. The Yankees are so good right now with the way they run and steal bases. If you give him too much, he can forget about pitching. You just try not to give him too much and overwhelm him." - Terry Francona on Chase Burns after his team’s win against the Yankees in their game on Sunday. 


Starting Lineups


Milwaukee Brewers
Christian Yelich (L) DH
Jackson Chourio (R) LF
Brice Turang (L) 2B
William Contreras (R) C
Jake Bauers (L) 1B
Garrett Mitchell (L) CF
Sal Frelick (L) RF
Cooper Pratt (R) SS
David Hamilton (L) 3B

Cincinnati Reds
Blake Dunn (R) CF
JJ Bleday (L) LF
Sal Stewart (R) 1B
Nathaniel Lowe (L) DH
Spencer Steer (R) 2B
Eugenio Suárez (R) 3B
Noelvi Marte (R) RF
Tyler Stephenson (R) C
Edwin Arroyo (S) SS

Statistical Leaders


Milwaukee Brewers
Batting Average:  Cooper Pratt (.368)
Hits:  William Contreras (83)
Home Runs:  Jake Bauers (13)
RBI:  Brice Turang (47)
Stolen Bases:  David Hamilton (16)
Wins:  Aaron Ashby (10)
Saves:  Trevor Megill (9)
ERA:  Jared Koenig (0.00)

Cincinnati Reds
Batting Average:  Blake Dunn (.289)
Hits:  Sal Stewart (72)
Home Runs:  Sal Stewart (14)
RBI:  Sal Stewart (53)
Stolen Bases:  Sal Stewart (11)
Wins:  Chase Burns (9)
Saves:  Emilio Pagán (6)
ERA:  Caleb Ferguson (1.50)

Managers:
Milwaukee Brewers: Pat Murphy (3rd season)
Cincinnati Reds: Terry Francona (2nd season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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