Miami Marlins vs New York Yankees Prediction, Preview and Odds - 04/03/2026

Game Time: 1:35 pm ET, Friday, April 3, 2026

Venue:  Yankee Stadium, Bronx, NY

Where to Watch:  MLB TV

DraftKings:  Moneyline odds:  Marlins +141, Yankees -171; Over/Under:  8 runs

Bet365:  Moneyline odds:  Marlins +140, Yankees -170; Over/Under:  8 runs

BetMGM:  Moneyline odds:  Marlins +145, Yankees -175; Over/Under:  8.5 runs

Miami Marlins:  5-1 (1st place, NL East)

New York Yankees:  5-1 (1st place, AL East)

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Miami Marlins:  5-1 last 6

New York Yankees:  5-1 last 6

The Marlins are entering this series off a win and won their 3-game series against the Chicago White Sox 2-1 in their last series. They enter this game with a 5-1 record overall and have a road record of 0-0. This is the series opener of a 3-game series with the Yankees on Friday and they have Thursday off as a day of rest. Their offense ranks 1st in the MLB with a .847 OPS. Sandy Alcántara was their starting pitcher on Wednesday while Eury Pérez is making his start in this game on Friday. He is 0-0 with a 3.86 ERA this season. His team won their only game this season with him making an appearance. In his last MLB regular season appearance, he allowed 3 ER, 2 HR, and 1 BB with 8 SO on 5 hits through 7 IP against the Colorado Rockies.

The Yankees are entering this series off a win and won their 3-game series against the Seattle Mariners 2-1 in their last series. They enter this game with a 5-1 record overall and have a home record of 0-0. This is the 1st game of a 3-game series with the Marlins on Friday and they have Thursday off as a day of rest. Their offense ranks 21st in the MLB with a .646 OPS. Cam Schlittler was their starting pitcher on Wednesday while Will Warren is making his start in this game on Friday. He is 0-0 with a 2.08 ERA this season. His team won their only game this season with him making an appearance. In his last MLB regular season start, he allowed 1 earned run, 0 homers, and 2 walks with 3 strikeouts on 5 hits through 4.1 innings pitched against the San Francisco Giants.

The current betting odds have the Yankees listed as a favorite in this game according to Draftkings Sportsbook. The Yankees have looked great in their games this season with their 5-1 record overall which has them right at the top of the AL East with the best record in the MLB to start the season. This is also going to be their home opener after a strong performance on the road in the first 2 series' they played. Meanwhile, the Marlins have looked great in their games this season with their 5-1 record overall which has them right at the top of the NL East with the best record in the MLB. They had a great performance at home in their first 2 series' of the year, but now they are playing their first road series. The Marlins were also beating up on 2 of the worst teams in the MLB to start the season, but now they are going on the road against one of the best and the Yankees have a huge pitching advantage in this one. Warren is up for the Yankees and he is off a great start in his first of the season. He only gave up 1 run in 4 innings and he has a great bullpen to back him up too. The Marlins are going with Perez in this one and he didn't look as great in his first start. He gave up 3 runs in a deeper start, pitching 7 innings, but their offense was a big part of those wins too. Their offense isn't going to look as good in this first road series with the weather being much colder now and the Yankees have barely given up any runs this year with one of the best pitching staffs to start the season, so everything points to the Yankees in this home opener. The best way to place a bet here is on the Yankees to win this game. 

Marlins Yankees Prediction:  Our MLB Pick for Friday, April 3, 2026 (1:35 pm ET start time) is Yankees 5 Marlins 2.

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Miami Marlins: 17-17 (+8.2 units) on the moneyline against AL East opponents. 66-83 (+27.2 units) on the moneyline as a road underdog of +100 or higher. 112-114 (+40.3 units) on the moneyline against right-handed starters. 30-15 OVER after 3 consecutive games versus an interleague opponent.

New York Yankees: 16-18 (-8.3 units) on the moneyline against NL East opponents. 96-67 (-17 units) on the moneyline as a home favorite of -110 or higher. 52-49 (-17.9 units) on the moneyline in an inter-league game. 20-9 OVER vs. NL teams allowing 4.0 or less runs/game on the season.

Miami Marlins:  C. Morel (LF) Ten Day IL - Oblique. A. Mazur (SP) Sixty Day IL - Elbow. E. Ruiz (LF) Ten Day IL - Oblique. K. Stowers (LF) Ten Day IL - Hamstring. M. Acosta (SS) Ten Day IL - Oblique. R. Henriquez (RP) Sixty Day IL - Elbow.

New York Yankees:  G. Cole (SP) Fifteen Day IL - Elbow. C. Rodon (SP) Fifteen Day IL - Elbow. A. Volpe (SS) Ten Day IL - Shoulder. C. Schmidt (SP) Sixty Day IL - Elbow.

“His at-bats have been outstanding. The patience, not missing his pitches. He’s found a couple holes and then really good swing on that last changeup to extend the lead for us on a no-doubter to right-center. He feels dialed in to me and obviously we know what he’s capable of.” - Aaron Boone on Ben Rice after his team’s win against the Mariners in their game on Wednesday. 

“Many negative things happened last year but that didn’t hold me back trying to be better. This year, I am going to give my best every time, win more games and be more aggressive in counts. Today, as a club, we did a tremendous job.” - Sandy Alcantara after their win against the White Sox in their game on Wednesday.

Jakob Marsee (L) CF

Xavier Edwards (S) 2B

Otto Lopez (R) SS

Liam Hicks (L) C

Connor Norby (R) DH

Owen Caissie (L) RF

Heriberto Hernández (R) LF

Graham Pauley (L) 1B

Javier Sanoja (R) 3B

Trent Grisham (L) CF

Aaron Judge (R) RF

Cody Bellinger (L) LF

Ben Rice (L) DH

Paul Goldschmidt (R) 1B

Jazz Chisholm Jr. (L) 2B

Amed Rosario (R) 3B

Austin Wells (L) C

José Caballero (R) SS

Batting Average:  Liam Hicks (.467)

Hits:  Xavier Edwards (9)

Home Runs:  Liam Hicks (3)

RBI:  Liam Hicks (12)

Stolen Bases:  Owen Caissie (1)

Wins:  Sandy Alcantara (2)

Saves:  Pete Fairbanks (2)

ERA:  Sandy Alcantara (0.00)

Batting Average:  Giancarlo Stanton (.500)

Hits:  Giancarlo Stanton (10)

Home Runs:  Aaron Judge (2)

RBI:  Ben Rice (5)

Stolen Bases:  Cody Bellinger (2)

Wins:  Max Fried (2)

Saves:  David Bednar (3)

ERA:  Max Fried (0.00)

Managers:

Miami Marlins: Clayton McCullough (2nd season)

New York Yankees: Aaron Boone (9th season)