Game Time: 7:30 pm ET, Saturday, September 12, 2026
Venue: Tiger Stadium, Baton Rouge, LA
Where to Watch: SECN+
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: LA Tech +35.5, LSU -35.5; Over/Under: 55.5 points
Bet365: Point Spread: LA Tech +35.5, LSU -35.5; Over/Under: 55.5 points
BetMGM: Point Spread: LA Tech +35.5, LSU -35.5; Over/Under: 55.5 points
Season Record
Louisiana Tech Bulldogs: 1-0 (0-0) (1st place, Sun Belt West)
LSU Tigers: 1-0 (0-0) (1st place, SEC)
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Louisiana Tech Bulldogs: won their last game at home against the Northwestern State Demons 80-6.
LSU Tigers: won their last game at home against the Clemson Tigers 51-10.
Louisiana Tech Bulldogs vs LSU Tigers Preview and Analysis
Louisiana Tech is entering this game with a 1-0 record overall and they have a 0-0 record in their conference games too. They are 1-0 in their home games, 0-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against Northwestern State 80-6. Blake Baker was the starting QB and he completed 10/14 passes for 232 passing yards, 3 touchdowns, and 0 interceptions. Trey Kukuk led the team in rushing yards with 50. Jalen Mickens led the receivers with 133 receiving yards on 3 receptions and 1 TD. Grayson Hardy and Sam Fongang each led the defense in that game with 6 tackles while Kaleb Coleman and Donovan Rieman each led the defense in sacks with 0.5. Alonzo Jackson Jr. came away with the only interception for them in that one.
LSU is entering this game with a 1-0 record overall and they have a 0-0 record in their conference games too. They are 1-0 in their home games, 0-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against Clemson 51-10. Sam Leavitt was the starting QB and he completed 16/28 passes for 230 passing yards, 1 touchdown, and 1 interception. Dilin Jones led the team in rushing yards with 113 and 2 TDs. Winston Watkins led the receivers with 110 receiving yards on 7 receptions and 1 TD. Princewill Umanmielen led the defense in that game with 2 tackles while Princewill Umanmielen led the defense in sacks with 2. Jordan Ross came away with the only interception for them in that one.
Louisiana Tech vs LSU Prediction
The current betting odds have LSU listed as a 35.5 point favorite in this game according to Draftkings Sportsbook. LSU has a 1-0 record overall this season and they looked great in week 1. There was a lot of questions surrounding this team with their new head coach and one of the most expensive rosters in the nation, but Lane Kiffin passed the test with flying colors. They challenged themselves in week 1 with a tough game against Clemson and they absolutely embarrassed Clemson. Clemson isn't ranked this season and they have definitely lost a step under Dabo these last few years, but they are still a solid program that will likely win over 8 games this year and LSU buried them 51-10. The game was over at halftime with the offense rolling, and Clemson couldn't do anything against that defense either. Meanwhile, Louisiana Tech has a 1-0 record overall this season, but they didn't challenge themselves at all. They are coming off an 80-6 win over a team from the FCS, Northwestern State, and that is a really bad FCS team too who lost to a lower division team in their season opener. Now they go on the road against a much stronger LSU team and LSU isn't going to hold anything back here. Lane Kiffin is going to be on a warpath all season trying to run up as many scores as he can and he already embarrassed a much better program in Clemson. Louisiana Tech doesn't stand a chance to even be competitive in this one as LSU looks to iron out any kinks they have before conference play starts. The best way to place a bet here is on LSU to cover the spread in this game.
Louisiana Tech LSU Prediction: Our NCAAF Pick for Saturday, September 12, 2026 (7:30 pm ET start time) is LSU 63 LA Tech 3.
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NCAAF Betting Trends
Louisiana Tech Bulldogs: 17-10 ATS in all lined games. 8-2 ATS as an underdog. 6-3 ATS when the total is between 49.5 and 56. 8-4 UNDER in road lined games. 7-2 UNDER when the total is between 49.5 and 56.
LSU Tigers: 10-17 ATS in all lined games. 1-6 ATS when the total is between 49.5 and 56. 4-7 ATS in non-conference games. 17-8 UNDER against FBS division opponents. 8-4 UNDER as a home favorite.
Key Injuries
Louisiana Tech Bulldogs: D. Benedix (WR) Questionable - Undisclosed. M. Calwise Jr. (WR) Questionable - Leg.
LSU Tigers: None.
Notable Quotes
“If we would have won close or ugly, the whole story would have been I screwed the whole team up. I have been criticized heavily the last two weeks, and I get it. But my job is to not please you and what you are going to write. My job is what I believe is right — and I believe we were fighting for what is right for those kids.” - Lane Kiffin after his team’s win against Clemson in their last game.
"In a game like this, you have to maximize your opportunities every snap. When you have an opportunity for a takeaway, you've got to maximize that. When you have an opportunity for (a tackle for loss), you have to do a great job of tackling.” - Sonny Cumbie on his team’s upcoming game against LSU this week.
Starting Lineups
Louisiana Tech Bulldogs
WR Mickens, Jalen
WR Shettron, Talyn
WR Calwise Jr., Marcus
TE Finley, Eli
QB Baker, Blake
RB Miller, Jaden
LSU Tigers
WR Elzy, Malik
WR Wilson III, Eugene
WR Watkins Jr., Winston
TE Green, Trey'Dez
QB Leavitt, Sam
RB Jones, Dilin
Statistical Leaders
Louisiana Tech Bulldogs
Passing: Blake Baker (232)
Rushing: Trey Kukuk (50)
Receiving: Jalen Mickens (133)
Touchdowns: Talyn Shettron (2)
LSU Tigers
Passing: Sam Leavitt (230)
Rushing: Sam Leavitt (113)
Receiving: Winston Watkins Jr. (110)
Touchdowns: Sam Leavitt (2)
Coaches:
Louisiana Tech Bulldogs: Sonny Cumbie (5th season)
LSU Tigers: Lane Kiffin (1st season)